Hydrastis canadense

by

Poisonings

I. Miss W-aet.75, suffering from chronic ulcer of leg, but general health being good, took by mistake on evening of August. 15th, 1862, 20 dr. of tinct. During night was restless. On morning of 16th experienced great sense of sinking and prostration at epigastrium with violent and long-continued palpitation; three greenish evacuations, with pain in bowels as if she had taken a drastic purge. In course of day she had flushes of heat over head, neck, and hands; these were succeeded by an erysipelatous rash, covering neck, palms, and joints of fingers and wrists. Irritation was maddening, with intense burning heat. These symptoms continued until the 22nd, when skin exfoliated; irritation remained in a slighter form for some day, and was always worse at night l (BAYES: in Hale.)

2. A patient, subject to sore-throats, had one involving buccal cavity. An infusion of hours was prescribed as a gargle, to be used 3 or 4 times a day. Misunderstanding directions she used a whole tumblerful in about 5 hours, at same time applying a cloth, lips and nose were very much swollen, and during day. Pimples appeared around mouth and chin resembling early stage of smallpox. Next day they began to vesiculate, on 6th to sink in centre, turn dark, and commence during, scaling off on 10th. (W. L. CLEVELAND; in Hale.).

Experiments on animals

I. Prof. Bartholow has made some experiments on frogs and rabbits, and proves that the alkaloid hydrastine is the true active principle, its characteristic effects having been simply repeated by sufficient doses of the fl. extr. His conclusion are as follows:

1 a. H belong to the excision-motor agents. It heightens perception, cutaneous sensibility, and reflex functions; and causes death by tetanic fixation of the respiratory muscles.

1 b. The spasms and convulsion caused by hours are central and spinal not peripheral.

1 c. H exhausts the irritability or motor nerves and muscles.

1d. H. acts on both the inhibitory and the motor apparatus of the heart, destroying their power of response to irritation; but the former function yields after the latter. The blood pressure is lowered. (MOHR, Hahn. Monthly, November, 1880.).

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Richard Hughes
Dr. Richard Hughes (1836-1902) was born in London, England. He received the title of M.R.C.S. (Eng.), in 1857 and L.R.C.P. (Edin.) in 1860. The title of M.D. was conferred upon him by the American College a few years later.

Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.
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