4 c. September 25, 1856. – Masticated two leaves in morning. On walking in forenoon had weight in chest with dyspnoea, and occasionally painful pressure in chest affecting breathing much less. 26th. – Recurrence of uneasiness in uvula, which next day had become pain, rather severe when swallowing; sense of swelling increased towards evening when there was decided elongation and reddening of uvula and its vicinity. Pain in throat went off gradually during following day.
4 d. October 6th. – Took early 10 dr. of tinct. In 1/4 hour tasteless eructations, surprising inactivity all forenoon, heavy, even sleepy, with frequent yearning. 17th. – Lachrymation of right eye on waking, slight reddening of conjunctiva and lids at inner angle; slight mucous discharge from both eyes all day. In forenoon surprisingly fresh, lively, and inclined to walk. ( Ibid.)
5. R. H. -, aet. 26, in good health save for occasional slight attacks of wandering rheumatism, and a papular eruption on back of hand. On October first, 1856, at 6 a. m., masticated four or five leaves for 15 morning. In 10 morning had scintillations before eyes; while writing, letters seemed to swim together on paper, and he seemed to be using two pens; feeling gradually came as of knocking above eyes; great tingling in ears. At 8, rather severe headache, sense of dryness in throat, greet humming in ears; vision is now clear. At 10, headache better, still heaviness in head and ringing in ears; oppressed feeling in chest; great nausea after breakfast. Food not relished at dinner. At 6 p. m., severe vomiting, twice, of watery mucus, without bitter or acid taste; after that strong taste as of leaves; urine dark brown. No stool to-day, in spite of several attempts; was awoke at 11 at night with desire for one, which proved firm and abundant. 2nd. – At 7 a. m., masticated two leaves. In 10 morning symptoms as yesterday, but headache less violent; heart beats strongly with oppression of chest; no nausea. 3rd. – Same mastication, and same symptoms of eyes, ear, and head. Much constipated with abdominal uneasiness. Again palpitation for 6 or 10 morning 4th. – Masticated one leaf at 6:45 a. m. masticated five leaves. At 7:15, found it impossible to continue reading, letters running together; fiery points passed downwards before eyes; dulness of head. At 9, violent headache directly above eyes; great ringing in ears, with deafens; no appetite for breakfast. AT 1 p. m., had still very heavy; very great palpitation. Dinner not relished; feeling as if he would vomit; great thirst; feet as if filled with lead. At 9:30, great weariness; bowels unrelieved to-day; urine small in quantity and of dark-brown colour. 8th. – Did not sleep much; bad taste in mouth, with great thirst; head still dull and confused. At 5 p. m., first motion for 39 hours, hard and knotty. At midnight awoke with urgent desire for evacuation, but without result. 9th. – From 9 p. m. masticated four leaves, and while doing so went to bed. IN 10 morning masticated four leaves, and while doing so went to bed. In 10 m. pressure in eyes; coloured vision; sparks pass downwards before eyes; great anxiety and palpitation; broke out into copious perspiration; violent headache over eyes; great nausea. At 11:30, vomited twice, with after – taste of leaves. Fell asleep towards 1, but was extremely restless, waking at least six times before 3; also bad dreams and constant respiration. Tolerable sleep 3-7. 10th. – Rose with great dullness in head, as after a debauch; no appetite; coated tongue, and bad taste. No stool to-day. 11th. Masticated two leaves, with same effect on eyes, ears, head, heart, and abdomen; also great thirst. In evening bowels moved, first time for 41 hour. On undressing next evening discovered on inner thigh a number of small red pimples; they itched dreadfully during night, so that he scratched till blood came. At 7 a. m., two more leaves, with usual results. Costive stool at 8 p. m.; continued itching and fresh pimples, and old ones do not itch so much. 17th. – Two more leaves with usual results; fresh pimples behind knees and horrible itching. [Writing November first, prover states that he
has since been uncommonly free from rheumatism, and that the old eruption on hand is greatly improved.] (Ibid.)
6. h. PEKAREK, aet. 9, a healthy, lively, and clever child. Proved a tinct. prepared from leaves dried 17 years ago. ON December 3rd took 10 and on 4th 15 dr. without effect. On 5th, 15 dr. In evening groaned (unconsciously) whilst writing. Drank lager beer without subsequent nocturnal enuresis which ordinarily occurs. 6th. – 15 dr. In evening while writing, some irregular or heavy breathing. At 10:30, uneasy turning in bed, and repeated raising of arm under head; indistinct talking during sleep; on a light being brought in, woke and stared with dilated pupils, and was a long time before he came to herself (all this abnormal). In morning confusion of head, disappearing after toilet and breakfast. Took 15 dr. At 10, headache, going off after dinner, somewhat listless and tired in evening. (Ibid.)
7. a. I made experiments with the infusion, which was of an insipid, grassy taste. When taken in evening it caused great uneasiness, discomfort, and sleeplessness; but in morning its action was much milder, causing loss of appetite.
7b. Dr. Archibald Smith once used infusion in place of tea, but felt in such a state of nervous excitement that he did not repeat the experiment. (POPIG, quoted in Ibid.)
10. Dr. STOKES, December 9th, 1857, took at 6 p. m. 10dr. of tinct. in water. During evening hearing became painfully acute, brain excited, and there was somewhat painful pressure on sides of head. In bed, pillows felt hard to neck and head; and, though very sleepy, he turned and twisted about all night, and woke tired and heavy next day., with aching shoulders. Dreams were of great activity. In night and next morning mouth and palate felt as if burned with pepper. 10th. – In evening took same dose, and had same painful constriction round head and dreamy excited state in night 11th. – Repeated dose morning, noon, an evening In evening buoyant and elated. Indisposed for food all day; night again dreamy and restless. 12th. – Same dose at 10:30 a. m. Stool 3 hours late, and less easy than usual, as if from dryness of rectum. Appetite still diminished and night dreamy.13th. – 10 dr. again. Stool as yesterday. After this digestion, aptitude for work and power of muscles became extraordinarily good, and continued so. He took no more med; but sleep continued full of active troubled dreams, notwithstanding which he awoke lively and vigorous every morning for about 10 during afterwards, when effects of proving faded away. (Monthly Hom. Rev., iii, 163.)
11. The warm infusion in small doses produces effects very much like those of ordinary tea, and, taken in larger quantities, agitation and inability to sleep. IN cold infusion, it heightens arterial tension. (MORENO Y MAIZ, Pract., i, 234)
12. Dr. LILIENTHAL, aet. 54, took 4 dr. of tinct. at 2 p. m., and half a teaspoonful at 4 p. m. an at midnight. At 4, fulness of head, as after wine, and dull pain over left temple; at 7, vertigo, with dulness in forehead, after a relished dinner; at 9, lazy and sleepy, indisposed to read; soon after midnight dose, sense of compression in region of short ribs; restless sleep, awake off and on the whole night. For next day or two fulness in forehead, as if it we heavier than rest of brain. On 4th day took half a teaspoonful at 7 and 9 a. m., whole at 2 p. m. Brain so muddled that he cannot red intelligently; slight pressing pain in left temple, with dullness of head; palpitation; stitches run in towards bowels, and in afternoon 4 mushy stools, without pain. On 5th and 6th day stools natural. On 6th days, at 5 p. m., a teaspoonful. Fulness and pressive pain in forehead, though near open window, worse towards 9 p. m. ON 7th days took teaspoonful of tinct. at 5, and of 3rd dil. at 7 p. m. Plagued all day with desire for stool, and sulphuretted hydrogen flatulence; fulness and tension in forehead with slight shooting in right temple, and dull feeling over whole brain, headache increased (especially over right eye) in evening, with burning of eyes; slight stitches in right chest, near sternum, about 4th rib; general restlessness; feels tired and weary, though not sleepy, must exert himself not to shut eyes; every symptoms passed off at 9 p. m., on being called into open air On 9th day took teaspoonful of 3rd, and had recurrence of frontal tension, with disposition to close eyes as before. On 10th and 11th days took frequent drop doses of 30th without effect. (HERING’S Mat. Medica, i)
13. ADELAIDE WILLIAMS. M. D., took small doses of tinct. for 2 days without effect. On 3rd day, 20 dr. Felt stimulated after increased dose; constipation; fine stitches in urethra before micturition. On 4th day took teaspoonful doses of tinct. and from 6th to 11th day drank freely of strong infusion. On 8th recurrence of stitches, and on 9th, of constipation. On 10th, hoarseness, with tickling in upper trachea, and some cough; menses, 2 days late, came on at noon, very profuse drug night, not in steady flow as usual, but in gushes, waking her from sound sleep. On this day and next, right temporal headache in morning, sharp on first rising, and all day on looking up; pain darts from temple in straight line to vertex, leaving sore feeling behind; same part hurts on coughing. Without date, – slept all night very restless and dreaming, and in all her dreams much hurried. ( Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.