3. NENNING. – His young women (see Acidum Hydrocyanicum, I, 26) were generally peevish and ill-tempered while taking drug. During a pressive headache, sudden attack (while standing) of vertigo and stupid feeling in head, so that she lost consciousness for a moment; headaches are frequently mentioned, sometimes very severe, in all parts, and variously conditioned. Excessively painful pressure and twisting deep in right eye, involving orbit, which is sensitive to pressure, during catamenia; similar pain from root of nose to behind left frontal eminence, with lachrymation of left eye, after cessation of which heat arose over whole body, with feeling as if sweat would break out; eyes always agglutinated in m. A few drops of blood from nose every time she sneezes. (5th d.); burning in both nostrils, as if they were sore. Cracked lips, and burning there. Toothache during menstruation. Burning on tip and numbness of back part of tongue and over whole mouth, and dryness in throat for 4 m. running on waking, disappearing after eating (13th d.). Cold feeling in stomach, as if ice lay in it. Stitches in epigastrium and hypochondria; abdomen sensitive internally and externally; so that she could not bear it touched, and was obliged to walk bent (11th d.). Painful urging to stool, followed by three attacks of diarrhoea, and afterwards tenesmus and burning in anus, with prostration of whole body (21st d.). Urine turbid, and burning after passing it. Menstruation irregular, sometimes too early, sometimes too late, accompanied by headache, toothache, and diarrhoea; often altered in quality. Thick albuminous leucorrhoea on walking. Much shooting in walls of chest, front and back, and tearing in limbs. Pruritus and itching pimples in many parts. Dreams terrifying. Mouth chilliness. (Ibid.)
4. SCHRETER. – Mental condition exalted, varying between extremes; much less headache noted than by others; illusion of vision, so that she feared a person sitting near her cutting paper would stick scissors into her eyes- they seemed just before her face; contraction over nose, with feeling of heaviness and pressure, as though skin were too short; great changes of colour in face, at one time red, at another pale; small depressed ulcer on left margin of tongue, sore and painful to touch; stammering when reading; swollen cervical glands, with tension and drawing pains, for 6 d.; every m. on rising nauseous taste in mouth, as if stomach was found, for 14 day in succession; orifice of urethra inflamed and agglutinated; great scraping of larynx as if sore, extending down into chest, with much tough mucus in chest, it is raised with difficulty, and threatens to suffocate her; palpitation, with vertigo and headache, – with congestion to head, heat and thirst, and itching in right eye, – with trembling of whole body and uneasiness; great weariness in hands and feet all d.; marked paresis of arms and hands, especially right; skin of hands becomes unusually dented by instrument with which she is working – shears or knifes; much and lasting heat; with thirst, anxiety, and restlessness. (Ibid.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.