From Aug. 30th to Sept. Ist urine was below normal in quantity and amount of urea, but slightly in excess in sp. gr.
9c. Same proved hot infusion of fresh root. Before retiring, Sept. 28th, 3ss. Soon much nausea, but no vomiting. 29th. -Pulse 68, regular. At 7 a.m. 3ss. Nausea returned; rumbling and weak feeling in lower bowel; headache, beginning in r. temple, soon sharp and stabbing, followed by confusion in head and vertigo; aching extends to meatus auditorius. Stool as usual. At 10:30 3ss. Feeling of goneness; severe pain in head; arms feel too weak to be moved; pains in joints reappear. At 2, 3ss. In 20 m., pulse 60, described by medical friend as “full, slow, irregular intermittent, dicrotic; at times feeble and readily compressed. Another, listening at chest, found “heart beating regularly for a short time, then fluttering occasionally and very feeble, then slow and laboured, now and then losing a beat;” he also noticed a clicking beat, for which he could not account. During afternoon and evening, slight darting pain in region of heart, feeling of weakness there, had to breathe deeply from feeling of suffocation. After this, flashes of heat followed by perspiration. Stool, as usual. At 5:20 pulse found for first 1/2 of m. 18, for last 1/2 32; at 6 it was 66, intermitting, which it continued to do that day and n. Took no more of drug; slept well; on rising, pulse 60, fuller and more regular; stool mushy, yellow flatulent; pain and weakness of heart returned; sensation as if it beat slowly, then fluttered, then went on regularly again; impulse at times very indistinct; sharp pain at intervals at inferior angle of l. scapula. Head symptoms continue, but with less vertigo. More or less aching in joints. Whole frame very weak.
Writing on Jan. 30th, prover states that after last experiment head and heart symptoms disappeared gradually up to Oct. 15th. Bowels continued over-active for some time, but were then normal, save that sphincter still felt relaxed. While too frequent (3 times a d.) he would feel bloated in abdomen, with slight pain here and there; then urgent desire for stool, making him feel that it might escape prematurely. This always occurred immediately after eating. The usual symptoms followed the stools; also considerable itching at anus. Appetite never better. Joint and scapular pains also continued long; and little boils appeared on face and thighs.
During days of last proving, urine was normal in quantity, slightly in excess in sp. gr., and considerably so in urea (454 gr. as compared with 369 in health.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.