10. Dr. FLOTO took one dose of 1x, and experienced following symptoms:- Soon after taking it pain on vertex; emptiness in head, sensation of faintness, as if all blood had left brain, with anxiety. On walking in open air, had watery running from nose, with sneezing; tickling in larynx, with sensation of sticking, several coughs are induced, larynx feels swelled; stitches in left breast; difficult breathing, with constrictive pain in larynx and wheezing, oppression of chest towards right side. Had also drawing pain with rigidity near angle of lower jaw, first in left then in right side, but longer in left. Being awakened by noise in night, could not go to sleep again for 2 hours. (Ibid.)
11. Dr. KITCHEN took one dose each of 1x and 2x. Nervous and vascular excitement, as from alcohol, constituting a feeling of hilarity; pulse one third more frequent than usual, and tense. After lying down in bed twitchings in left deltoid muscle, and in a few m. one in right. Tensive pain in fleshy part of left thumb, with numbness and sensation of swelling, lasting about 1/2 hour (30 minutes). A feeling as after a debauch the previous night; dull headache, with a gnawing, tensive pain, and soreness in eyes and superciliary regions, lassitude, disinclination to occupation, reading, etc., and inclination to stretch; with occasional yawning. Relief by walking in the cool open air. (1 day after 2x). (Ibid.)
12. Dr. NEIDHARD took 1x and 2x trits. Seems in its primary action to diminish the power of concentrating his ideas, and afterwards to increase it. Greater presence of mind; the relations of the world seem to be clearer to him. He feels more composed than usual, and very much exhilarated. Great cheerfulness of mind, quicker in thought and action. Whole forenoon unusual vivacity and power of concentration, which is still more decided in afternoon. Giddiness the whole day. Fullness in forehead above eyes. Pain in left temple, extending as far as lower jaw (1.1/2 hours). Jerking in left temple. Augments in 1st hour secretion of mucus from throat. Slight sickness of stomach. Qualmishness of stomach, with sickness (6 hours), with sensation of grasping in stomach, very transient (in a few seconds). Slight gnawing burning in stomach, and eructations (1.1/2 hours). Pressure in stomach (in a few minutes). Wakes up at night with most violent pressive pain, like a heavy weight in pit of stomach; it comes and goes at intervals of 5 minutes, but diminishes in force at each renewal. It lasts altogether about 2 hours. Discharge of flatulency relieves pain (from 5 drops of oxalic ether taken in morning). In evening after tea pyrosis, with much emission of flatulency and pressing downwards. Every evening pyrosis. Loss of appetite. Unusual thirst at 3 a. m. (2 days.) Dull aching pain in right side of abdomen, whole afternoon, on a small spot. Pain round navel like colic, repeatedly, but always after symptoms in head. Sensation of soreness in abdomen. For 1/2 hour after retiring continued pain in left hypochondrium. Pain between hypochondrium and navel, on left side, like a development of flatulency (1/2 hour). On sitting down after a walk, violent effort to discharge flatulency (as from small spot on l. iliac region), with sensation as if part would burst. Pain in region of navel, with painful pressing down towards anus, and flatulency. Pain in region of navel, with emission of flatulency in night. Whole evening rumbling in bowels with pressing downwards. Twice passage of bowels during day. In evening slight pain in region of right kidney. Urine to pass water, with copious discharge; water is of a lighter colour than usual. Excitement of sexual function, repeatedly. Sensation of contusion in both testicles. During walking in evening pretty severe pain and heaviness in both testicles, shooting along spermatic cords; worse on right side. Jerking in testicles and spermatic cord. Slight cough, from tickling in larynx and trachea; also sensation of soreness in larynx. Immediately after lying down in bed at night, palpitation of heart for 1/2 hour 3 n. consecutively. Sensation of numbness in sacrum. Slight lameness and stiffness in lower extremities. Itching on neck. On a spot on right index finger, where a cut from a penknife had healed 4 days ago, a very painful pustule appears (2nd). Continual and vivid dreams, always of a frightful nature; wakes up often and dreams constantly. Sleep very restless but without dreams (2nd days). After dinner, sleepiness and profound sleep while in the sitting position. He is more inclined to sleep at night than usual. Creeping of cold, particularly from lower part of spine upwards. In evening, after tea, sneezing, with chilliness. General sensation of heat. Pulse increased in frequency, 100 to 108. General excitement in evening. Symptoms seem to be excited and aggravated by movement, as pains in bowels, testicles, kidney, back, etc. Oxalic acid has a decided action on joints: ankle, knees, hip, wrist, shoulders. Extreme lassitude of body. Symptoms of oxalic acid occasionally intermit for some hour or a day, and then return in a diminished degree. Some, who are generally much affected by cold weather, appear better able to bear it. (Ibid.)
13. Mr. E. SMITH took one dose of 1x. Dull headache on vertex. Heaviness in forehead and vertex (in morning after taking acid in evening). Eructations and passage of flatulency downwards. Flatulent colic, like as if he had eaten unripe fruit, on waking up at night, below navel, which is increased by movement after getting up; pain diminishes during rest and returns periodically (night after taking it). In morning, after breakfast, on walking about, some pain returns; gets better about 9, and disappears entirely at 12. Sensation of soreness on touching, all round navel. (Ibid.)
14. Dr. WILLIAMSON took same in evening. Unusual power of concentration of mind. Hilarity and cheerful. Pain along base of occipital bone, returning several times during first 2 days. Pain in both orbits, but worse in left. A sticking pain in left hypochondrium (3 hours). Pain in descending colon, followed by free evacuation of mushy stool in evening (1 hour). Similar pain returned the second evening. Copious discharge of urine at 5 a. m. after taking it. Sticking pain in right hip-joint. Smarting soreness around neck, as if chafed by collar. (Ibid.)
15a. Dr. SHARP, at 7.5 p. m., pulse 72, took gr. 1/10, in 10 m. of water. At 7:10 pulse was 76, soon fell to 70. Soon after 8, giddiness and a little nausea; a loose motion, with a little griping. At 10:30 pulse was 60.
15b. At 11:50 a. m., pulse 82, took gr. 1/20 in 100 m. of water. Pulse in 5 minutes rose to 86, then fell to 80. After going to bed that night heart made its beatings sensible in an unusual manner, and attracted attention. Next day bowels moved 3 times, relaxed, which is also unusual.
15c. Took two doses of gr. 1/100. After first pulse fell from 72 to 68; but second reduced it no farther. (Essays on Medicine, p. 787.).
Poisonings
1. J. Phillips, aet. 57, muscular and robust, at 8 a. m. swallowed by mistake 3ss of acid in teacupful of water. Vomited after drinking warm water, but not subsequently, in spite of emetics, &c. When seen at 9 complained of excruciating agony in lower part of back, extending down thighs; body extremely cold and clammy with sweat; skin of arms, chest, and face mottled; pulse very feeble and contracted; no pain in throat or abdomen, even when letter (which was distended) was pressed upon; muscular prostration very great; complained of weight and powerlessness of limbs; restlessness extreme, requiring frequent change of posture; respirations natural; perfect consciousness and unaltered expression. During forenoon, constant involuntary discharge of fluid matter from intestines. At 3 p. m., pain in back and thighs continuing unabated, he had also some little pain in abdomen, slightly increased on pressure; had recently vomited a pint of thick black fluid; pulse still more feeble. At 7 p. m., pain in abdomen increased to utmost; could not bear slightest pressure; had several copious alpine evacuations, consisting of a thick black offensive fluid, in which were seen a number of bloody shreds; pulse imperceptible; respiration oppressed; countenance exhibited great anxiety; was sensible, and complained of having lost his sight: in this state he continued till 9 p. m., when he died. P. M., 10 hours after death. upper part of body much discolored; abdomen tumid. On opening peritoneum, great distension and discoloration of small intestines. peritoneum, great distension and discoloration of small intestines. Mucous membrane of pharynx and oesophagus as if scalded; villous coat of stomach pulpy, in some places of black colour, in others highly injected. Mucous lining and peritoneal coat of small intestines much inflamed. Pelves of kidneys considerably more vascular than ordinarily and this extended a little way through ureter. Mucous membrane of larynx and trachea, and lungs themselves, intensely inflamed. (HEBB, Lond. Medorrhinum Repository, N. S., ii, 475.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.