SOME time ago I had a very strong desire for grape fruit, instead of taking the usual half grape fruit at breakfast, took two whole grape fruits last thing at night with the minimum of sugar or no sugar, usually with no sugar. After a fortnight or so I began to suffer from an almost continuous headache low down at the back of the head which took various forms and is therefore difficult to describe. After some time headaches of different forms appeared sometimes at the back of the head, sometimes in one of the temples, and in other parts of the head. I was rather surprised because I have never in my life had any headaches except an occasional dull headache easily attributable to a dietetic indiscretion which never lasted more than a few hours.
The thought of hardening of the arteries within the skull occurred to me first, but in the absence of confirmatory evidence I interrupted myself about my diet and left off grape fruit. In a few days the daily headache had disappeared and has not reappeared. I feel firmly convinced that grape fruit, Citrus decumana, was responsible, but I have not been able to find anything in literature except the brief notice in Boerickes Materia Medica: “Tinnitus, head noises and ringing in ears. Sensation of pressure in the temporal region.” While taking two grape fruits every night I also noticed fullness and pain in the liver region, accompanied by a swelling of the liver, about an inch beyond the ribs.
It is not quite clear to me whether the liver symptoms also were produced by the grape fruit, but it seems to me quite possible as there is no apparent cause for that symptom, which also is new to me. I do not live on a diet which is likely to cause swelling of the liver and since abandoning grape fruits the liver condition has become practically normal. It may be that grape fruit potentised in the usual way may be useful for enlargement of the liver and headache. Possibly some of your readers may have made observations similar to mine and it may be that people troubled with headaches and a sluggish liver will do well to abstain from grape fruit. It is worth noting that many people say that they cannot eat oranges because they “upset their liver.”.