Tuberculinum has been started and defined to be a nucleioproteid and represents those groups of compounds of one or more molecules of protein with nucleic acid. Like the nucleio- albumins, it is broken down by the gastric juice into albumin and nucleic acid, with the production of xanthin bodies. These xanthins are actually leucomains, allied to the ptomaine groups and have in their composition carbon, hydrogen, nitrogen and oxygen, approximating three molecules of the former three elements to one of the last named. Excretitious products of metabolism in the body, they are found both in the tissues and in the body fluids and are noted definitely in calculi formation.
All of these leucomains are physiologically active and many of them are severely toxic. Tuberculinum is mentioned by Dorland as being tuberculin pura, a therapeutic and diagnostic preparation from the pure culture of the tubercle bacillus, extracted with 80 percent alcohol. Our own preparations are made from the tubercular glands as preferred by Kent or from the dried tubercular sputum as mentioned by Dewey.
Going in for a bit of chemical comparison, we find that the formulas of nitroglycerine, dynamite and trinitrotoluol are very closely related to that of our nosode, the variation being that it has a bit less of nitrogen and oxygen. We might secure that oxygen by way of the oxidation processes within the body and so find it easy to understand the explosive that might acute to what was originally a physiological product.
However, we do not need to presume on its bombing effects because of its similarity to known explosives for we know it possesses such type of action from a study of its true and clinical provings. The component parts of any ring or radical may be definitely variable until brought together and given a title and similarly do we know that many miasmatic and dyscrasic backgrounds may be just as variable in their disease projections.
Hahnemanns research into the tubercular manifestations and their appearance in other aberrations of health than the parent disease, is a case in point. It is common knowledge that tuberculosis, having existed in a progenitor, may be traced and found as an altered active condition in offspring. Daily we are able to trace functional disturbances, lowered organic development and below par performance to an ancestral tuberculous entity. There is, quite possibly, not the conveyance of the complete disease but certainly the dispositional lean to develop, by excitation, a like tuberculous state, within that family line and group. There is the spraying forward, from the forebear, who is definitely diseased, the influence which we find expressed in lowered organic resistance and metabolic aberrations of the normal.
Because of parental tuberculosis, young generations exhibit neurosis of many kinds. Hysterias, tics, choreics, in the central field; predispositional cold occurrences, recurrent bronchitis, pneumonia susceptibility, the spasmodic and catarrhal asthmas, notably in the respiratory fields. Lymph tissue involvements, glandular upsets, dyscrasias of the stomach and the intestines, with even true ulcer formation and the advent of unexplainable diarrhoeas. All of these fall within the scope of projected effects of a foregoing tubercular involvement. Your own case histories can easily confirm this presumption.
The source of origin considered, we could expect the remedial effects to be deep in action and because of the destructive, shattering action of tuberculosis itself, we could expect nothing from its nosode save upheavals which would bring to light and uncover many unsuspected states and symptoms. Acting upon the vegetative system, wide destruction is manifest, constitution is altered and depletion is rapid. Recoveries from illnesses are found to be at low ebb and relapses are frequent and intense. Vital weakness is shown by cases which break down and go to pieces even after well indicated remedies act.
We know that we have a definite field of symptomatology action for this remedy but we also have a second field of usefulness. This is when we surmise that there may be unexpressed disease condition which we should secure. One of the chief satisfaction of this “housecleaner”is its effect upon the action of other well indicated remedies which do not seem to have the deep or lasting effect that is desired. An interdicted dose of this nosode will resolve the case so that just such effect may be secured.
Tuberculinums force of action would be best in the lean, gaunt, tall, weary individual. Always tried, always anxious, always changeable. Patient with questionable tubercular background. They are cured of one thing, only to slip back or have a new thing explode into the limelight. There is a hopelessness and weariness of life that matches the end results of real tubercular disease. Such shattering is manifest in the mental as well as the physical field. It involves the vascular system and we have fearful headaches which are long being recovered from. Meningitis we are aware of and also we know that the nosode is of especial value in the treatment thereof.
Throughout the body there is a steady loss of tone and both flesh and muscle support is lost. Organs sag and prolapse is common. Emaciation ensues and the general exhaustion leads even to muscular spasm. Toward the particulars we note that the once sunny and sweet disposition becomes morose, sulky and melancholic. Intense periodical headaches even to true megrim. Lymphatics enlarge. The chest shrinks and with it there is cough, dyspnoea, nocturnal perspiration, bronchorrhoea and suffocative attacks even with much fresh air. Drum belly appears and there is unaccountable diarrhoea, especially before breakfast. There is a blotching of the skin with itchings and also ringworm.
Three cases are presented in which the action of the nosode is noted, in relation to juvenile asthma.
Boy, age three years, having asthma for the past year. Family history involved tuberculosis on the mothers side, the grandfather, two brothers and a sister being tuberculous. THe mother, one of those washed-out blondes, thin chested and stooped: her face, all eyes.
Father s history negative although his work as a meat cutter required his going and coming in iceboxes so that he had many colds and recurring bronchitis. Active t.b. undemonstrable in either of the immediate parents. Personal history of the small patient included delayed dentition, flabby tissues, pot belly, recurrent eczematous patches and difficult adjustment of diet and considerable diarrhoeal history.
For a period of six months he was treated with Calcarea carb; Sulphur Calcarea sulph. and Bacillinum without much perceptible result. It was a helterskelter asthma with no great responses to any irritant although pillows, bedding, room and so forth were carefully checked as well as the diet scrutinized with no determined modality. If he improved one time on a prescription at another time he didnt. Seemingly a true Calcarea patient, he failed of response to it and Sulphur intercurrently didnt improved effects.
At this time, influenza led the parents to take him to allergy clinic some two hundred miles away and he went through the mill for six days and was tested for everything form house dust to pollens and food. He was found sensitive to house dust and Johnson grass Treatment was outlined and closely followed. They prescribed everything thinkable to secure a result.
Adrenalin relieved a little but mostly he wheezed along regardless of effort in his behalf. At the end of their prescribed term he was practically unchanged. During this treatment his asthma had been attended by recurrent showings of the eczema and diarrhoea. Repetition of his Calcarea sulph. Over six weeks time fell flat. He was then given a dose of Tuberculinum CM. Skinner and placebo to last a month. His mother reported every four or five days.
About the fifth day after the nosode was given he had a furious attack of asthma which lasted all that day. It was not interfered with save for steam inhalations. In ten days following he had two more severe attacks irregularly placed, and the wheezy breathing was evident each day. The next two weeks evidenced only the wheeze and that seemingly was decreasing in amount.
Coincidentally the skin cleared and he has had no further eruption nor irritation from it. His general health is excellent, his development of the best. There has been no further scrutiny of his diet,nor is he protected from dust or other things and he even has a cat. Follow-up through a period of six years records no attacks of either the asthma or the eczema and there has been no diarrhoeal disturbance. Would you suppose that the Tuberculinum had something to do with this result?.
The two following cases show the results of a general exhibition of the nosode in bringing clarity to fogged up cases and developing a lead to the curative prescription.
Boy, age eight years, Came to the office with multiple ringworm. Was placed under ultra violet radiation and given Sulphur 6x. The skin soon cleared and an interval of a month went by. He then returned with a development of almost daily asthmatic disturbance, which were steadily increasing in intensity. He seemed robust and had no such affliction hitherto, but there was no doubt about his having asthma.
Tuberculosis was reported in the mothers father and one brother. The mother was fat, flabby and indolent, with much pelvic pain and constant weariness. The father was in good health but for long had worked in cement construction and was given to crops of boils. He was a fairly successful alcoholic. Generally the house was ill kept and they were indifferent as to ventilation. A very careful examination was made.
The chap was negative to both No. 1 and No. 2 P.P.D. tests. X-ray of the chest was negative. Blood work was well within normal limits. Urine negative. He had mumps and measles and colds but without undue severity. In reference to his asthma, mostly anything might be recorded. It occurred at night; it came during the day. Hot days, cold days, sunny and foggy. Came when inactive; came when busy. Came with colds and without. Came at any hour and was worse at no hour. Pets or no pets, food, it didnt matter. He just started in to wheeze and kept it going until he got weary of it and quit.
He wasnt nervous and there were no aggravations from anger nor punishment. He was not repressed nor did he have any inferiority complex. In the beginning as for youthful asthma, Aralia racemosa was given. There was no result. Sulphur was then given with recollection of the old ringworm, but with no effect. Phosphorus and Calcarea phos. and others were tried but he wheezed on and time was going by with considerable uneasiness on the part of the parents. After a thorough head-scratching. Tuberculinum was given again, using the CM. potency and single dose. Placebo followed to carry along.
For a week there was only a slight diminution in the usual daily wheeze. Then the daily embarrassment gave way to attacks of more marked asthma and little by little these attacks developed an aggravation time of about two to two-fifteen each early morning. There was no doubt but that we were having a change- about in the manifestations of the case. These attacks so continued to recur at the named hour for over a period of ten days. In addition to this swing around the mother reported that the boy seemed more nervous and jumpy and that he hung close to her and would not go out freely to play.
Also that several times in the day he complained of being so empty in his stomach but that she didnt help his feeling by feeding him a lunch. That seemed as though we had a lead coming out and upon that report we gave him kali carb. in the 1M. potency of Skinner. One powder helped in nearly every way but died out about the fifth day. The medication was repeated, giving him three doses in nine days. All through this period he improved. The goneness and his dread and his asthma showed sings of ending. He took two more doses in the subsequent month and in that term was fully relieved.
In the ensuing eleven months he remains well. Lastly. Visited a boy of five years, in 1936, who was having a severe case of asthma. Was met by skinny droopy mother who looked to be plenty tired. Weak voiced, flat chested and sickly smile. Father was of the same general trend. There was also a choreic daughter to be noted.
The patient was a thin, talkative, nervous chap, even though busy getting his breath. He had been having scattering attacks of asthma for the past year and they were accompanied by some hay fever also. Had an attack of “flu” two years before and was finicky about his eating and had a good deal of indigestion. This was his most severe attack thus far. For his very evident distress he was given a hypodermic of eight minims of adrenalin. Awaiting this relief, his mother reported that the attack had begun with nausea and vomiting which had recurred off and on the entire day. There was pallor, vomiting and exhaustion, with cold perspiration attending. After temporary respite by the injection he was placed on Antimonium tart. 3x. every two hours for the time.
During the improvement which followed the case was gone over. X-rays were negative, general and blood work negative in the main. His condition seemed fair but there simply wasnt enough to him. He went along attack identical with the former one. This time Antimonium tart. didnt touch him but Ipecac. did. In the ensuing four months he repeated the attacks with this or that remedy mostly relieving for the while. There was too much changeableness to the case and to the required remedies to suit. He was carried along awaiting a red line to guide a bit. There seemed to be no such intention so we decided that we might try to blow the lid off and see what was underneath. He was given the same prescription as the former case.
That medication helped like fury. It looked as though it might be only one that would be needed. His attacks recessed and his general health improved greatly. His rest and strength were alike improved. He did finely for over three weeks and then things veered about and his asthma reappeared, but in a vastly different manner. He would have no trouble during the day until about one hour after his return from school in the late afternoon. This become so fixed that they brought him home via auto where he had formerly walked, but the attacks appeared anyway. The attacks would come abruptly and hold on until about an hour after he went to bed, giving them an aggravation time of from about four to ten p.m.
After that hour he steadily improved and rested well though the night and the following morning was as free as if there had never been any asthma at all. Occasionally he would miss one or maybe two days week from attacks. There seemed to be far more grief in the right chest than in the left side. About this point two more symptoms put in their appearance.
He only ate part of his lunch and breakfast and the evening meal were about one-third consumed when he would push his plate away, saying that he was just too full to eat any more. He had no indigestion to all intent nor was there any belching. His mother reported, however, that about the house and even in his sleep that he seemed to pass so much gas from his bowels. Potatoes or bread or onions or whatnot did not, however, give any disagreement. He could eat anything but the amount was very little as compared to his former wants.
This gave us an odd idea that Lycopodium might be something that the chap could use and based upon the results he most surely took it on. He received it in the 1M. potency of Skinner. In all he has had seven doses in as many months of time. His case cleared most satisfactorily though on a much slower scale than the former ones, possibly because he seemed to be dividing the medicinal effects between his asthmatic relief and his general physical betterment. Follow-up of the case reports no further recurrence of the asthma and continuing physical growth throughout the period of eleven months since his last prescription was made. BERKELEY, CALIF.
DR. GRIMMER : This paper shows the observation, powers and keen analysis that are required of a homoeopathic physician. It also shows that the philosophic requirements of the law were followed out.
I can verify similar cures with Lycopodium, especially its relation to ringworm. It is very frequently a remedy that will wipe out your ringworm in a short time. Sometimes, even with no other basic symptoms, if there are no other symptoms when I get a case of ringworm I use Tuberculinum.
DR. BOND :I would like to ask the doctor what kind of Tuberculinum he used, avian, human or the bovine type?.
DR. FARRINGTON : I arise to add my commendation to this paper. It illustrates to me very important points. One, that nosodes seldom cure alone; another, indicating the wisdom of waiting on the action of a remedy until the symptoms have changed and seem to have expended their force; third, that the picture of a remedy is not complete if some of the well known keynotes are lacking, as in the case where Lycopodium is prescribed.
DR. SCHMIDT : I will just add that the French school has worked along the line of the nosodes, and have put out some very valuable indications of four types of tuberculin, Kochs tuberculin, the residual Koch, Denys tuberculin and Marmoreck tuberculin. I have published some abstracts of those publications in the Pacific Coast Journal of Homoeopathy.
DR. TROUP : In relation to the type of Tuberculin used, it was the aviary. It was used presumably at my insistence by a very good doctor.