DRUG SENSITIZATION AND DESENSITIZATION REPORT OF MORE CASES



“Photofluorograph of chest revealed great heart enlargement”.

(Signed)-Frank W. Burge, M.D. 3-16-44.

This patient was systematically desensitized to the following: Digitalis, Natrum mur., Strepto., Colon bacillus, Pluto water, Opium, T.B., Phenobarbital, Carters little liver pills, Codeine, Tobacco, Bromo Selzer and Alophen.

Treatment was begun March 7, 1944. On March 16 she said she felt very well, but still conscious of heart fluttering. On March 30, 1944, the patient stated that she felt all right in spite of irregularity of pulse; however, much less so than when first seen. She continued to report improvement on April 3, 6 and 10. Treatment was not discontinued so long as the patient reported increased improvement. Her case was remarkable from the viewpoint of those at the office and at her home.

She was not treated according to any pathologic diagnosis. That had been done before she came to us and proved a failure. She was not treated homoeopathically but isopathically with many sensitinogens, (according to the list of drugs furnished by the patient and her sister). The largest list of drug sensitizations thus far found:.

Alka Seltzer

Alumin

Aloes

Alophen

Alvesen

Aminophylline

Anacin

Analgesic slave

Cherocol

Chloral hydrate

Chlorotone

Cinnamon

Citrocarbonate

Coca-Cola

Cocaine

Cocoa

Codeine

Coffee

Cough drops

Carbon tetrachloride.

Conaylac seeds.

Coryza tablets.

Delvinal.

Digitalis.

Doanes kidney pills.

Doca.

Empirin.

Eno salts.

Ephedrine.

Ephedrine and amytol.

Epinephrin.

Ergot.

Eserine.

Eskay neurophosphate.

Estivin.

Estrogen.

Ex-lax.

Face powder.

Father Johns tonic.

Fel Sol.

Feosol.

Formaldehyde.

Ginger ale.

Gluco Phed.

Glyco thymoline.

Granya seeds.

Grove;s cold tablets.

Hair (cat, dog, cow, goat, horse).

Hair dye (inecto).

Asafoetida

Aspirin

Asthmodore

Benzedrine

Benzoin

Bismuth

Bisodol

Bromide of sodium

Heroin

Insulin

Isohalent

Ivory soap

Lextron

Lint

Lithia

Liver extract

Luminol

Mazon

Metaphed

Midol

Milk of Magnesia

Mineral Oil

Mistol

Molle Shaving Cream

Natures Remedy

Nembutal

Neoprontosil

Neo Synph.

Neuro phosphates

Neurosine

Novalene

Novatrophin

Nutmeg

Onion

Olive pills

Opium

Paint

Painodyne

Papes Cold Comp.

Paradine and sulphathiazole

Paragoric

Peony

Peppermint

Petroleum

Phenobarbital

Phenolax

Phenol

Pinoleum

Pluto water

Progesterone.

Bromo Seltzer

Camphor

Carters Liver Pills

Caroid and Bile

Cascara

Castor oil

Cedar wood

Cepacol

Propadrin

Prostigmin

Pussy willow

Quinace (acetanilid)

Quinidine

Quinine

Rabellon

Rem

Resinol soap

Red Top Snuff

Ruex shampoo tint

Sal Hepatica

Salicon

Salvitea

Sod. Salicylate

Sod. bromide

Silus aqueous nose drops

Serutan

Seconal

Sulfadiazine

Sulfanilamide

Sulfapyridin

Sulphathiazole

Talcum powder

Tea

Thiolar

Thyroid

Theobromine

Tobacco

Trexcene

Tums

Vercolate

Vicks nose drops

Vicks salve

Vitamins

Wheat flour (rye, graham)

Whisky

Wood alcohol

Yellow lax

Zilatone

Zonite.

The next case is odd in that I have never seen one just like it before. He is 59 years of age, tall and erect. He suffered for 20 years with a loose and productive cough and recurring attacks of intermittent fever.

Nasal breathing was obstructed on account of mechanical faults in the nose, however the nasal obstruction was added to by vasomotor paresis which in turn was due to the local treatment that were given him prior to his visit to me.

His history revealed that he was taking 48 different palliatives and some of these were compounded. I hesitate to take up the time to list them all. Alphabetically from A to G they are:.

1. Anacin.

2. Aspirin.

3. Asafoetida.

4. Bromo Seltzer.

5. Bicarbonate of soda.

6. Carters little liver pills.

7. Castor oil.

8. Cascara.

9. Cinnamon

10. Codeine

11. Cocaine

12. Empirin

13. Eskays neurophosphates

14. Ex-lax

15. Formaldehyde

16. Garlic & parsley

17. Glyco Thymol

18. Menthol cough drops.

To try to desensitize a patient to 48 drugs one at a time would require at least that number of visits, so I decided to give the patient at least 3 at a time, choosing, as carefully as possible those to which he appeared to be most sensitive.

The first day (Feb. 16, 1944) he was given by intracutaneous test: Codeine, Tobacco, and T.B. On the day following he was given Alcohol, Tobacco and Quinine, all in high potencies. His heaviest reaction the day following was to alcohol. It was 4 m.m. in diameter, red and underrated.

On Feb. 26 he was given Coffee, Sodium bromide and Natrum mur. By March 4th the patients cough was appreciably improved, however he continued to cough a little.

March 6th he reported that he slept well the past two nights, something he had not done for a long while. He had no cough during the night.

Photofluorograph of the chest revealed “bilateral flattened diaphragm.” (Signed)-F.W. Burge, M.D. Feb. 16, 1944.

At this writing the records go to April 27, 1944. The complete report of this case would be more voluminous than the one reported entitled Just One Case.

In both cases the patient made excellent progress as the result of nothing else than bacterial and drug desensitization. I fail to see how any other kind of treatment could possibly have succeeded.

PAPESS COLD COMPOUND: (Acetanilid, Ext. Belladonna, Powdered Aconite root, Phenolphthalein, Gum Turpentine).

It is rarely possible to find a patient who has been sensitized to a single drug. As a rule the patient first takes a drug, usually one that is not indicated and when it fails, as fail it must, he tries another and when that fails still another until it is found that he is eventually sensitized to many. The longer his ailment continues the greater the number of different drug sensitizations and the more difficult becomes the problem of restoring health, which is not possible until all of the drug sensitizations have been discovered and appropriately treated with desensitizing doses of the same sensitinogens.

No sensitinogen except the specific one that brought about the sensitization can possibly succeed in effecting a cure any more than an attack of typhoid fever will act as a prophylactic against whooping cough or any other dissimilar disease. Arsenic in sufficiently small dose can act curatively in a case of severe arsenical poisoning as I have observed more than once, but belladonna or any other dissimilar drug cannot.

TYPHOID FEVER SENSITIZATION: An interesting case of which is that of a City Hall detective, at one time a fine physical specimen. For a while before we saw him he was considerably broken in health mostly from drugs, so much so that his case could be divided up into many; however I shall restrict myself to the discussion of a single phase-typhoid fever sensitization and desensitization. As a recruit of World War I he was given the usual three injections of typhoid fever vaccine. He claims to have been made very sick.

He recovered sufficiently as to make a very creditable soldier, having been wounded a number of times and received as many decorations including the Purple Heart. Having made a number of studies of immunity and sensitization following attacks of the natural disease I decided to make a skin test with typhoid vaccine in the 4M. potency. The following day he presented a very large skin reaction, the largest I have ever seen. The negative phase lasted a few days after which he developed the positive with marked improvement. I had observed the same effects in a few other cases but in other infections notably.

I have made similar experiments in other infections notably pneumonia which have already been reported. However, the pneumonia sensitization was not made by vaccines as in the typhoid case. Could the improvement in the typhoid fever sensitization have been effected by any other than the isopathic remedy?.

MAGNESIUM SULPHATE: The next case is one of Mag. sulph. sensitization. Like the previous case Mag. sulph. was not the only drug to which the patient had become sensitized. On the other hand it is the one that stood out most prominently. All told he was sensitized to 20 drugs among which were included Anacin, Aspirin, Benzedrine, Bromo Seltzer, Cascara sagrada, Coffee, Ephedrine, Feosol, Natures remedy, Histamin, Mineral oil, Phenobarbital, Tobacco, Lugols solution of Iodine, Vicks Nose drops, Vicks salve, Seventy per cent of these drugs are capable of producing the symptoms for which the patient sought relief-Menieres syndrome.

In spite of the many poisonous drugs taken by the patient the one that did the most damage as prove by the diagnostic and therapeutic tests was Mag. sulph. The cure was effected by the same sensitinogen in high potency (isopathically).

VICKS NOSE DROPS: A middle aged female, a Salvation Army officer, had used Vicks nose drops over a prolonged period until she became severely sensitized. She suffered mostly from an irritating discharge from the nose both anteriorly and posteriorly. Almost any kind of nose drops or spray containing a petroleum base is capable of doing the same thing. Her history was lengthy but in part is irrelevant for which reason the report is made as briefly as possible, merely for the purposes of bringing out the fact that Vicks can produce the very thing it is intended to cure. Further more, its mere discontinuance is beneficial but not so much so when combined with specific desensitization treatment. In this as in other cases of its kind the results were prompt and better than is possible by any other form of treatment.

George W. Mackenzie