Glycerin represents a deep acting and a long lasting effective drug, in its effect on the animal economy, in contra-distinction to the short, rapid, commonly used compound known as nitroglycerin, which is very short in action, and is summed up as a simple vasomotor dilator and circulatory depressant.

Glycerin is a liquid obtained by the decomposition of vegetable or animal fats or fixed oils, containing not less than 95 per cent. of absolute glycerol (C3H8O3), a triatomic alcohol existing in fats and fixed oils in combination with the fatty acids.

Glycerin represents a deep acting and a long lasting effective drug, in its effect on the animal economy, in contra-distinction to the short, rapid, commonly used compound known as nitroglycerin, which is very short in action, and is summed up as a simple vasomotor dilator and circulatory depressant.

Pure glycerin, in its dynamized form, goes deeply into the human economy. The chemico-physiological and pathological changes that result from the formation and ingestion into the system are completely verified by its symptomatology and its curative effects. Glycerin, in its dynamized form, proves itself to be a basic element of extreme value. It seems to have a remarkable effect on balancing the general metabolism. I cannot help but repeat that it is a deep and positive acting remedy in the potentized form.

The proving, as presented, represents verifications covering at least four years. The proving has been conducted along modern scientific lines of investigation. The provers were examined thoroughly before and during the proving. The proving represents the work of nine male and three female provers, and controls.

THE GENERAL THERAPEUTIC RANGE OF GLYCERIN: Glycerin has proved itself to be a tissue builder and is of undoubted value in marasmus. It seems to affect most of the organs and tissues of the body. It has proved of undoubted value in diabetes, influenza-pneumonia, neurasthenia, many forms of gastroenteric disease, various types of headache, enlargement of the liver, various types of senile debility, acute catarrhal conditions of the mucous membrane of the naso-pharynx, and nephritis of the aged.

GENERAL SYMPTOMS: The first symptom developed by Glycerin is headache with a sense of fullness in the head, and throbbing, < by motion; dullness of the mind; a sense of mental and physical weakness; restless sleep and dreaming; much physical languor, almost to a state of utter prostration. Loss of appetite, constipation, profuse urination, with traces of sugar. Catarrh of the naso-pharynx.

MENTAL AND HEAD SYMPTOMS: Headache during the entire day. Heavy feeling in the head, better after every meal. Throbbing in the temple arteries, < on exertion. Frequently confused; inability to analyze work; forgetfulness as to details. It positively produces a severe headache two days before menstruation. This was entirely relieved when the flow was established. Sensation of fullness and pressure in the occiput. Flushing of face, followed by a sallow, sickly look.

NOSE: Stoppage of the nose, an early symptom of all provers. Nose is stopped up, but there is considerable post-nasal dripping. Discharges from the anterior nose; first thin and watery, later profuse and yellow. Excessive sneezing, usually worse in the evening. The discharge from the anterior nose is irritating. The coryza is < toward evening. A teasing, dry sensation in the nose, causing sniffling, and a sensation of crawling on the mucous membrane.

MOUTH: Excessive dryness of the mucous membrane in the mouth with thirst, and drinking water relieves but for a short time. Sense of heat and feverishness in the nose, throat and mouth; sweetish taste in the mouth. Mouth pasty, insipid; lips become dry and cracked.

CHEST AND HEART: Sense of fullness and tightness in the chest. Glycerin produces a hacking cough and a great sense of weakness accompanies the short hacking cough; the cough seems to follow the coryza. Palpitation with dyspnoea. Chest seems too full, or as if the heart took up too much room. Concussive, jarring cough.

BACKACHE: Fulgurating pains in the left lumbar region, < on changing position. Dull pain across the lumbo-sacral region, passing into the left inguinal region. There is a sense of weakness and prostration accompanying the backache.

STOMACH AND ABDOMEN: Loss of appetite in the beginning; later on, excessive hunger, enjoying meals and feeling strong. The provers expressed themselves as never having felt stronger or better in their lives than after a good, substantial meal. Fermentation, short, incomplete eructations, burning in the pit of stomach and along the oesophagus; gurgling in the bowels. After taking Glycerin for three weeks this disappeared, with a sense of rejuvenation in the abdomen. Constipation was a constant and very permanent symptom in the early part of the proving. Stools were hard, dry, sometimes ball-like, always with great urging, and in one case with fissuring of the anus. Chronic constipation was cleared up.

URINARY ORGANS: The primary effects are to produce profuse and frequent urination, annoying the patient at night, which had never been the case before. There was produced a burning sensation in the urethra during micturition, occasionally severe pains during the act, which extended to the shoulders and upper part of the chest. The analysis of the urine in one case showed sugar, and this has been verified as curative in clinical work. The specific gravity increased to 1,030.

MALE: Seminal emissions which had been regular, ceased during the proving; testicles and scrotum became firmer, and a general sense of tonicity took place; the remedy did produce a tonic effect on the urogenital tract.

FEMALE: After taking Glycerin continually for five weeks the provers (two nurses) who had been regular and normal in their menstrual flow from adolescence, developed a very profuse menstrual flow, lasting from ten to twelve days, with bearing down heaviness in the uterine region. The flow was bright red, with occasionally a small clot. After discontinuing the Glycerin, the next flow was normal as to quantity. Three months afterward, after the persistent use of Glycerin for four weeks, the same condition of profuse bright flow ensued, accompanied by weakness; a general sense of exhaustion and < when moving about on the feet. The flow came on about five days ahead of time. The weakness was accompanied by some perspiration and coldness of the feet, similar to Calc. carb.

TISSUES: Severe pains of rheumatic type from head to feet. Deep, hard, painful aching in the deltoid muscles, the trapezius and the pectoral muscles, lumbar muscles and hips. The effect on the provers feet was interesting. They were painful and hot, with a sensation as though they were enlarged. The muscular pains were of a remittent type; they would come, last a while and go, only to return again. After the primary effects of the drug were over the majority of the provers gained in weight and had a sense of wellbeing about them.

NERVOUS SYSTEM: Severe nervousness throughout the day, with increased urination. The more excitable and fidgety the patients felt, the more frequently they were called upon to urinate. Tired, weary, lackadaisical sensation, with much mental disturbance about trifles. Gloomy at times, typical neurasthenic state. In the beginning sleep was restless, disturbed by dreams of a nondescript character, and fullness in the head, with a feeling of indifference and general broken-up state in the morning. Later on the provers slept soundly, a quiet dreamless sleep, and awoke feeling like new men.

SKIN: Acne vulgaris cleared up entirely on two students while proving Glycerin. After the primary effects of weakness and exhaustion passed and the prover began to feel well, the acne gradually disappeared.

FEVER: Both male and female provers developed rise in temperature and also increase in blood pressure to the extent of from 20 to 30 millimeters.

A critical analysis of the provers shows, first, that Glycerin is capable of disturbing the nutrition of the vital economy in its primary action, and secondarily, that it seems to improve the general state of nutrition.

Compare Lactic acid; Gelsemium.

I will offer a few clinical cases showing the depth of action of pure Glycerin.

CASE 1. Patient, a homoeopathic physician in Philadelphia aged 61 years. Refused insurance on account of albumin casts and sugar in urine; has been under his own care for months; developed a severe infection on neck, six inches in diameter, with all the forms, etc., of carbuncle; was operated on by Dr. Herbert S. Leopold very successfully; systolic pressure 170 millimeters; extreme nervousness; profuse urination with a specific gravity of 1,030. Sugar in urine, etc., examined by a Philadelphia chemist; extreme debility, prostration, etc. Glycerin in 30th and 200th eliminated sugar and albumin in three months, and patient gained fifteen pounds.

CASE II. Mr. S., baker, age 66 years. Diabetes for years; weakness; dyspnoea; headache; urine saccharose, with acetone; great debility. No albumin or casts. He was placed on strict diet and given Sulphur, Phosphoric acid, Uranium nitrate, Arsenicum album, Syzigium jambolanum, and potentized blood. Glycerin was then given with the result that the urine cleared up, a good appetite developed, and after a period of two years sexual vigor returned.

CASE III. C.H.H., a baby two years old, Drs. Yeager and Macfarlan assisting. Influenzal pneumonia. Profuse coryza and dyspnoea. Consolidation in both lungs; weakness and debility after twelve days. Glycerin 200 was given, and a complete recovery ensued, with improvement at once.

The writer wishes to give public acknowledgment to the two ladies and his faithful students, Mr. Carl Vischer, Mr. Hobart and Mr. Kropp.


William B. Griggs