This case should be considered alongside case 2. Where Nux vom. had a similar “loosening” effect. If this is maintained, life can be much easier for the patient and, though one can scarcely expect reorganization of destroyed cartilage, this has occurred (Dr. Boyd quoted such a case years ago). The destruction in the case resembles that present in Charcot joints and in the joints of syringomyelia, in both of which the cause is neurogenetic and not toxic.