Clarke gives the toxic effects of homeopathy drug Podophyllum and its therapeutic uses in non-toxic doses in his book The ABC Manual of Materia Medica and Therapeutics, published in 1901….



      Bilious diarrhoeas, passages large and frequent. Duodenitis with hot, watery stools. Green or yellow stools driving one out of bed in the morning. Dark or light-colored hard dry stools. Constipation of infants. Dark urine. Jaundice.


      Hypersecretion of bile with violent bilious vomiting, cutting pains and bilious purging. Intense congestion and even ulceration of the duodenum and other parts of the small intestine.1.


      Extractum podophylli, 1-5 gr.

Extractum podophylli, 1/12 -1/4 gr.

Resina podophylli, 1/12 -1/4 gr.

The second and third decimal triturations of the resin are very effective.


      Biliousness with nausea, giddiness and bitter risings, Tendency to bilious vomiting and purging.1.

(Second or third decimal triturations of the resin).

Duodenitis with jaundice: catarrhal inflammation of the small intestine with hot watery stools.1. (The minute dose).

Highly colored motions with cutting pains, especially if they drive one out of bed in the morning.1.

(Third decimal trituration).

Migraine accompanied by the bowel conditions of podophyllum.1.

Constipation of infants. The passages are large, dry and light colored. (The second decimal trituration of the resin one to four times a day).

Portal congestion, jaundice, very dark and constipated, or light-colored passages. Dark urine. (Produce physiological effects by use of the resin).

George Hardy Clark
Clark, George H. (George Hardy) 1860-1941 was the author of: Homeopathic Treatment of Asthenopia; Lee and Clark's Cough and expectoration : a repertorial index of their symptoms; The A B C Manual of Materia Medica and Therapeutics; A system for the care and training of children; The Black Plague and Its Control.