Clarke gives the toxic effects of homeopathy drug Grindelia and its therapeutic uses in non-toxic doses in his book The ABC Manual of Materia Medica and Therapeutics, published in 1901….



      Weakness of the cardiac and respiratory functions. Spasmodic asthma. Bronchitis with spasm of the bronchial tubes.


      Gastric uneasiness. Pupils dilated. Insensibility. Paresis or paralysis of the heart and of respiration.


      Extractum grindeliae fluidum, 10-60 m.

Administer in mucilaginous or syrupy vehicle, or in milk.


      Spasmodic asthma. (Twenty to thirty drops every half hour or hour).

Spasmodic difficulty of breathing, from pulmonary and cardiac diseases.

Bronchitis with bronchial spasm.

Whooping-cough. Weakness with impaired appetite.

George Hardy Clark
Clark, George H. (George Hardy) 1860-1941 was the author of: Homeopathic Treatment of Asthenopia; Lee and Clark's Cough and expectoration : a repertorial index of their symptoms; The A B C Manual of Materia Medica and Therapeutics; A system for the care and training of children; The Black Plague and Its Control.