Clarke gives the toxic effects of homeopathy drug Cuprum and its therapeutic uses in non-toxic doses in his book The ABC Manual of Materia Medica and Therapeutics, published in 1901….



      Intestinal cramps from catarrhal condition of the bowel. Cramps of the abdominal muscles and of the calves and feet. Gastro-intestinal catarrh, or ulceration of the bowel with dysenteric discharges and tenesmus. Chronic diarrhoea. Catarrhal and ulcerated state of the mouth.


      Catarrhal condition of the mouth. Nausea and vomiting. Abdominal burning, pain, tenderness and distention. Gastro- intestinal catarrh. Colic. Abdominal cramps. Ulceration of the bowel, dysenteric discharges, tenesmus.1. Trembling, cramps, convulsions. Paresis and alternation of sensation.2.


      Cupri acetas, 1/10 – 1/4 gr.

Cupri sulphas, 1/20 – 1/2 gr.

Cuprum ammoniatum, 1/10- I gr.

Minute doses, the second or third decimal trituration of the sulphate or acetate, are most generally useful.


      Gastro-intestinal catarrh, especially where the bowels are relaxed.1. (Sulphate of copper in doses of one-twentieth grain before each meal).

Dysentery. Ulcerated condition of the bowel, tenesmus.1. (One-twentieth grain of the sulphate every three or five hours. Irrigate bowel with ten grains to the pint of water).

Chronic diarrhoea.1. (One-sixteenth grain of the sulphate before each meal).

Catarrhal gastro-enteritis after acute exanthematous diseases.1. (One-twentieth grain of the sulphate every four hours).

Cholera infantum.1. (Arsenite of copper, third decimal trituration. One tablet at intervals of from fifteen minutes to one hour).

Intestinal cramps from catarrhal condition of the bowel. Constipation of diarrhoea may be present.1. (Third decimal trituration of arsenite of copper. Tablet at intervals of from one to three hours).

Vomiting of pregnancy.1. (Very minute dose of the sulphate or acetate, in water, every two or four hours).

Catarrhal and ulcerated condition of the mouth, eye, etc.1. (Wash with one-half to two grains of the sulphate to the ounce of distilled water).

Cramps of the muscles of the calves and feet.2.

Cramps and vomiting of cholera.1-2.

Local and general convulsions from retrocession of the acute exanthemata.2.

George Hardy Clark
Clark, George H. (George Hardy) 1860-1941 was the author of: Homeopathic Treatment of Asthenopia; Lee and Clark's Cough and expectoration : a repertorial index of their symptoms; The A B C Manual of Materia Medica and Therapeutics; A system for the care and training of children; The Black Plague and Its Control.