Clarke gives the toxic effects of homeopathy drug Cimicifuga and its therapeutic uses in non-toxic doses in his book The ABC Manual of Materia Medica and Therapeutics, published in 1901….

      Actea Racemosa-Black Cohosh.


      Passive pelvic congestion at the menopause with subinvolution of the uterus. Headache with profuse flow at the menstrual or climacteric period. Mania or melancholia during pregnancy and after confinement. Rheumatic pains in the various muscles and joints, which may be accompanied by arthritic deformities.


      Giddiness, dimness of vision, severe headache.1. General relaxation great prostration, nervous tremors.2 Pronounced cerebral disturbance, drowsiness.3. Increased pulmonary and cutaneous secretion.4. Heart action weakened.5. Pains in spine, muscles and back.6.


      Extractum cimicifugae fluidum, 20-60 minims (preferred).

Tinctura cimicifugae, 60-120 minims.

Extractum cimicifugae, 5-20 grains.

The third decimal trituration of the extract Macrotin is very effective.


      Common cold with profuse discharge.4.

Chronic bronchitis with profuse purulent discharge 4.

Phthisis, much expectoration, weak heart.4-5.

Dilated heart.5.

Fatty heart.5.

Languid circulation.5.

Muscular rheumatism, especially lumbago and rheumatic neuralgia.6.

Pleurodynia, lumbago, torticollis.6.

Rheumatic pains in most of the joints, but with scarcely any pain or fever. Thickening of tissues and bone may be present.6.

Rheumatoid arthritis.6. (Fluid extract).

Chorea of childhood, especially at time of puberty.2.

Passive pelvic congestion at climacteric period.2.

Atonic amenorrhoea.2.

Subinvolution of the uterus.2.

Miscarriages due to irritable uterus or prolapsus uteri.2.

Pleurodynia dependent upon uterine derangement.2-6.

Suppression of the menses or lochia from cold or mental emotion, with severe pain in the head, back and legs. Muscles stiff and sore. Bearing down pains.1-6.

Great mental disturbance during pregnancy and after confinement.2-3.

Puerperal mania.3.

Puerperal melancholia.3.

Sinking at stomach headache and irritability at climacteric period.1-2.

Headache in nervous, hysterical women at menstrual or climacteric period, flow frequent and profuse.1-2.

Spermatorrhoea where organs are relaxed and irritable.2.

George Hardy Clark
Clark, George H. (George Hardy) 1860-1941 was the author of: Homeopathic Treatment of Asthenopia; Lee and Clark's Cough and expectoration : a repertorial index of their symptoms; The A B C Manual of Materia Medica and Therapeutics; A system for the care and training of children; The Black Plague and Its Control.