Clarke gives the toxic effects of homeopathy drug Bryonia Alba and its therapeutic uses in non-toxic doses in his book The ABC Manual of Materia Medica and Therapeutics, published in 1901….



      Splitting headache worse on the slightest motion. Dry mouth and tongue. Dry, very painful cough, scanty expectoration. Must support the chest while coughing. Pleurisy with stitching, tearing pains and serious or fibrinous exudate. Acute meningitis in adults. Tongue and lips dry and cracked. Thirst. Restlessness.


      Frontal headache, vertigo, epistaxis. Fever.1. Cough, with pain in the chest. Inflammation of trachea, but not of the bronchi. Slight serous expectoration. Lungs hepatized. Pleurisy with serous exudation.2. Liver sensitive to pressure. Watery or serous stools. Colic.3. All synovial membranes injected, with serous effusion.4.


      Congestive headache with feeling of bursting or splitting, relieved by pressure and increased by stooping.1-4.

Splitting headache, bilious disturbance, dry mouth and tongue and nocturnal delirium.1-3-4

Acute meningitis of adults.1-4.

Dry, severe cough, caused by tickling sensation behind the sternum. Scanty, serous or blood-stained mucous expectoration. Pains severe, must support the chest while coughing.2.

Pneumonia with some pleuritic involvement.

Bronchial tubes almost free from mucus.2.

Pleurisy with serous or fibrinous exudate.2.

Pericarditis, acute, with exudation.4.

Stitching and tearing pains in serous and fibrous tissue, not apt to change location.4.

Joints much reddened and swollen. Pain increased by motion and relieved by pressure.4.

Usually the lips and tongue are dry and cracked. Thirst. Restlessness, but much pain upon movement.1-4.

George Hardy Clark
Clark, George H. (George Hardy) 1860-1941 was the author of: Homeopathic Treatment of Asthenopia; Lee and Clark's Cough and expectoration : a repertorial index of their symptoms; The A B C Manual of Materia Medica and Therapeutics; A system for the care and training of children; The Black Plague and Its Control.