Clarke gives the toxic effects of homeopathy drug Aesculus Hippocastanum and its therapeutic uses in non-toxic doses in his book The ABC Manual of Materia Medica and Therapeutics, published in 1901….

      Horse Chestnut.


      Haemorrhoids, large and dry with aching in lumbar region.


      Use second or third decimal dilution internally, and ointment of the drug locally.


      Aching in the sacro-lumbar region. Must sit down to obtain relief.

Large dry haemorrhoids. Sense of fullness and of dryness in the rectum.

Rectum and anus inflamed and tender. Large haemorrhoids with but little bleeding.

George Hardy Clark
Clark, George H. (George Hardy) 1860-1941 was the author of: Homeopathic Treatment of Asthenopia; Lee and Clark's Cough and expectoration : a repertorial index of their symptoms; The A B C Manual of Materia Medica and Therapeutics; A system for the care and training of children; The Black Plague and Its Control.