Clarke gives the toxic effects of homeopathy drug Acidum Benzoicum and its therapeutic uses in non-toxic doses in his book The ABC Manual of Materia Medica and Therapeutics, published in 1901….

      Benzoic Acid.


      Color of the urine deep red, odor very strong and offensive. Strong smelling urine associated with incontinence, albuminuria, offensive diarrhoea, rheumatism, etc. Vesical catarrh with phosphatic urine. Unhealthy, sloughing wounds. Fissured nipples.


      Acidum benzoicum, 10-20 gr.Tinctura benzoini,15-30 gr.

Tinctura benzoini composita, 30-60 m.

Sodii benzoas, 5-30 gr.

Ammonii benzoas, 5-30 gr.


      Color of urine deep red, odor very strong and offensive. (Benzoate of sodium).Ammoniacal urine from action of ferments in bladder. (Benzoate of ammonia, twenty-grain doses twice a day).

Phosphatic calculi. (Ammonii benzoas long continued).

Incontinence of urine depending upon irritability of the lining membrane of the bladder. Urine strong smelling. (Benzoic acid, two to ten grains).

Vesical catarrh with phosphatic urine. (Benzoate of ammonia, twenty-grain doses).

Albuminuria with strong smelling urine. (Benzoic acid, one or two-grain doses).

Watery, copious, excessively offensive stools, usually with strong smelling urine. (Benzoate of sodium, three to ten-grain doses).

Acute articular rheumatism, with strong smelling, high- colored urine. (Benzoate of sodium, one hundred to two hundred grains per day).

Diphtheria. (Free insufflation of benzoate of sodium).

Unhealthy sloughing wounds. (Apply cloths saturated with the tincture).

Chapped hands. (Ten to fifteen drops compound tincture in ounce of proper vehicle).

Fissured nipples. (Compound tincture in glycerin).

George Hardy Clark
Clark, George H. (George Hardy) 1860-1941 was the author of: Homeopathic Treatment of Asthenopia; Lee and Clark's Cough and expectoration : a repertorial index of their symptoms; The A B C Manual of Materia Medica and Therapeutics; A system for the care and training of children; The Black Plague and Its Control.