Feeling of fatigue.
Malaise, depression, headache, somnolence, oppression of breathing, tightness of chest, nausea.
General fatigue in morning; sensation of faintness; great weakness in lower extremities, esp. from knees down to feet.
Terribly tired, so that she can scarcely walk.
General excessive fatigue after a short walk, so that he must lean on his companion.
Emaciation (lost six pounds in fourteen days, twenty pounds in five weeks).
In parts affected throbbing pain.
Leucocytosis; diminution of oxyhemoglobin.
Oxyhemoglobin first diminished then increased (Henoque).
Feeling well, but decidedly losing flesh.
Acts principally by very acute irritation of internal organs affected (in the same way as in external organs), causing intense redness and great swelling.
Actual inflammatory processes (not mere hyperemias), and esp. active proliferations, occur to an intense degree, in (1) edges of existing ulcers; in (2) neighboring lymphatic glands, esp. bronchial and mesenteric.
Lymphatic glands present a quite unusual degree of enlargement, and notably that form of medullary swelling, characteristic of acute irritations, which is caused by rapid proliferation of the cells in the interior of the glands.
Leucocytosis: various infiltrations of white blood corpuscles over affected parts, esp. around the tubercles themselves.
Enormous dangerous swellings in parts near ulcers (even where the surface of the ulcer becomes clean), causing dangerous constriction.
Phlegmonous swelling resembling erysipelatous edema of glottis and retropharyngeal abscess.
Where tubercle is associated with any other specific disease, reaction is so slight as to be scarcely discernible (Heron).
Syphilitic cases are refractory to reaction (Heron).
Children bear the treatment well (Wendt).
Tuberculinum, a typical case: Howard L., 28 years of age, a resident of Attleboro, Mass., was indisposed in the fall of 1898, troubled with hoarseness and gastric ailments. A neighboring physician was called who had attended the young man’s family for many years. This physician commenced in September, 1898, to inject Tuberculin (Koch’s), and up to December had injected his toxin twice a week for several weeks, and then once in two weeks the remainder of the time.
The result? At the time of the commencement of this treatment Mr. L. could work and eat comfortably; soon his stomach rebelled against food and the bowels became constipated, his hoarseness increased and distressing, suffocative spells set in every forenoon, lasting an hour or so; he would then be able to breathe well the rest of the day.
In January, 1899, I was summoned hastily in the night and found him laboring for breath, the noise of his breathing audible from the street. His first words were: “My God, help me; relieve me, Doctor, or I shall die.” Expectoration was scanty, dark green, lumpy, tubercular matter. Examination of the throat revealed a larynx full of tubercular nodes. I saw that his end was near, and told his parents with whom he lived I would rather they would call their family physician. But as they insisted on my keeping the case, I prepared some medicine which relieved him, but the next morning he was again worse, and from that time on was in agony from efforts to get breath. To relieve him intubation (through the mouth) was resorted to, but he could not keep the tube in. He died that afternoon, his great agony being amel. only by resort to chloroform applied locally. This man had been wild in his youth, had gonorrhea several times, and of diathesis tubercular. I asked him if he had told his former physician these things and he said he had. This case is typical as far as the use of Tuberculin by injection is concerned, or of a score I could mention who have died under the hypodermic use of Tuberculin in this vicinity the past two years.
Miss. Mary E. A., 29, University student, one brother living in poor health. Mother, several aunts and rest of the family died before thirty of tuberculosis. In July, when 11 years old, was severely poisoned with ivy, and has annual attacks in summer ever since. Menstruated at 13; early, full, scanty, dark, clotted, exhausting, dribbles for a week; omits in June, July and August every year. Stomach and abdomen bloated agg. in summer. Perspires easily on single parts. Hands and feet edematous. Nape and occiput heavy; painful. Mental labor; her college work can only be done with great effort. Restless, dreamful sleep, unrefreshing. Feet and hands cold and damp. Summer heat exhausts her. Leucorrhea: acrid, profuse, brownish-yellow, offensive, running down to the heels in large quantities. Not relieved by bathing.
Case of cancer of the breast, so diagnosed by best allopathic authority in Boston; no history of grief or traumatism. The most peculiar symptoms about it were its tubercular-small hard nodules in the gland, a superficial string extending to the axilla.
Previously had suffered from severe headaches; since the growths appeared, headaches ceased. The nipple was retracted. On account of tubercular character of growths, the history of former headaches, which were similar to those of Tuberculinum, I gave the patient one dose. In 48 hours burning, lancinating pains began in the growths; had previously suffered from burning pain which was palliated by sedatives. The burning, lancinating pains continued two or three days, then gradually disappeared. The retraction of nipple was less marked, the tubercles softened, the pains disappeared and general health promptly improved.
Mr. G. A. T., 28, dry goods salesman, light complexion, mental, motive temperament, active, wiry, well nourished. Father and three uncles died of pulmonary tuberculosis, leaving him the only living male representative of the family; is strictly temperate, uses no coffee, tea, beer, or tobacco. Has suffered for nine years from involuntary emissions, with or without erections, and with and without dreams; weak and exhausted for two days following emissions; has six or eight per month. Has had some of the best men of both schools in the city caring for him, and the last six years under homoeopathic treatment, and for three years under one of the ablest members of this association.Cases.
Mrs. S-, aged 27, Denver, catarrh of nose, throat and larynx; cough severe agg. by lying down; for ten or fifteen minutes after retiring coughs severely, loosens some tough mucus which can neither be raised nor swallowed. Night-sweats if warmly covered.
Morning diarrhoea: watery, profuse, gushing, at 6: 30 A.M.; a slight motion, turning in bed, necessitates getting up in a hurry, with a rush. Rumbling, gurgling in abdomen as if quarts of water were in stomach and bowels. By careful eating can go rest of day without. Going without noon-day meal stool is natural, but it would not affect morning diarrhoea. In morning, weak; exhausted. In afternoon, feels fairly well. Excessively nervous during menses. Last three periods have been ten or fifteen days late and more scanty than usual. Under the care of one of our best homoeopathic prescribers has had Aloe, Sulphur, Podophyllum, Gamboge and Rumex.
Profuse, watery stool two or three times a day.
Constant urging for stool. Formication.
Loose stool; slight tenesmus.
Constant, ineffectual desire.
Loose, yellow colored stool, with considerable straining; three stools since 5 P.M., attended with much thirst and borborygmus.
Griping pain with bearing down in lower part of abdomen; some relief after stool.
Stool pale yellow color.
Sensation of drawing and constricting of sphincter.
Profuse, watery, ill-smelling, like old cheese, at 5 P.M.
Sudden diarrhoea before breakfast, with nausea.
Diarrhoea, furious fever, burning hot skin, great heat in head, red, flushed face, eyes turned upward, quivering and rolling; peculiar fetid smell of body. – Burnett.Cholera infantum. – Swan.
Severe hemorrhage from bowels, cough; emaciation; family history of phthisis.
Anxiety, gloomy, melancholy humor.
Has lost melancholy expression she formerly had.
Is disposed to whine and complain; dejected mind, anxiety.
She is very sad.
Nervous irritation; aversion to labor.
Aversion to all labor, esp. mental work.
Sensibility to music.
Does not like to be disturbed by people; trembling of hands.
Felt positively ugly; personal aversions became almost a mania.
Trifles produced intense irritation and I could not shake them off.
Very irritable, want to fight, no hesitancy in throwing anything at any one, even without cause.
Memory weak, unable to think.
Comprehension and concentration almost impossible.
Great anxiety for future, otherwise marked indifference.
Great sleepiness and weariness; entire muscular system relaxed; desire to lie down all the time.
Nervous; weak; IRRITABLE.
Melancholy, despondent, morose, irritable, fretful, peevish.
Dejected, taciturn, sulky; weeps, but knows not why; naturally of a sweat disposition, now on the borderland of insanity.
Fretful, snappish, morose, depressed and melancholic, even to insanity.
ILL-mannered, quarrelsome; lies in bed and complains; lachrymose, weeps without any provocation, cannot help it.
IRRITABLE ON WALKING; NOTHING CAN PLEASE HIM; NOTHING SATISFIES.
Melancholy with marked hypochondriacal delirium.
Everything in the room seems strange, as though in a strange place.
Intense restlessness, and inward restlessness.
With every little ailment whines and complains; easily frightened, particularly by dogs; screams in terror when approached by a dog.
Anxiety, gloomy, melancholic humor.
Very restless in the evening when aroused.
Periodical anxiety and terror.
She is very sad, dejected, and complains continually.
Nervous irritation; averse to physical or mental labor.
Indifferent; forgetful; averse to all labor, especially mental work.
Extremely sensitive to music.
Sensibilities dulled; with chill and aching in the head, back and limbs.
Somnolence; loss of vital power; great physical weakness.
Does not like to be disturbed; trembling of hands and feet.
Soporous, dazed condition; unable to find the right way; is confused; surrounding appear strange.
Memory weak or lost; unable to think or comprehend.
Comprehension difficult; must read a paragraph several times before he can understand it.
Sopor; somnolence; with dyspnoea.
Coma: profound, lasting three days, with temperature 106.
Delirium and serious meningeal symptoms, following an injection of Tuberculinum.
Complete unconsciousness; stupor and stertorous breathing.
Insanity; acute or chronic, with a family history of tubercular affections.
When the best selected remedy fails to relieve or permanently cure in a marked tubercular diathesis, with a tubercular family history.
Despondent, discouraged, feel as if I would rather die than live.
Although naturally of a sweat disposition, became taciturn, sulky, snappish, fretful, irritable, morose, depressed and melancholic, even to insanity.-Burnett.
Vertigo, esp. in morning; heavy with obstruction of eyes; is obliged to lean on something; by bending down, esp. by rising after bending down; with palpitation; with nausea; with backache in morning; after dinner.
Great heat in head; flushes of heat after dinner; sensation of heat in head in evening.
Headache: deep in forehead; deep in temples; on vertex, with sensation of heat; from neck to forehead; in morning, passing away in afternoon.
Sensation of heaviness on vertex.
Headache with obstruction of sight.
Headache with vertigo.
Piercing pain in forehead from 10 A.M. to 3 P.M.
Headache in evening; in afternoon.
Frontal headache in morning.
Headache with rushing in ears.
Headache in morning with bleeding of nose.
Headache from neck to forehead; burning, piercing.
Colossal hyperemia of pia matter and brain substance; extreme engorgement of vessels on the surface, internally dusky red; tubercles presented no retrogressive changes (arachnitis). (Sensation as if brain were squeezed with iron band.-Bac.) Headache agg. by motion.
Sick-headache commencing about 8 A.M., increasing in severity through the day; very changeable, leaning the head to one side would increase the pain on that side.
Brain seems loose and rolling around from side to side.
Darting pain in occiput, extending down the spine.
Headache commencing about 10 A.M., increasing until 3 or 4 P.M.
Pains erratic, changing place rapidly; first in one place then in another, not amel. in any position.
Headache in evening 8 P.M. neurotic, first in one place then in another, over one eye then the other, then the occiput and down the spine.
Headache in the afternoon, worse from going up stairs, better in open air.
Severe headache and vertigo in afternoon, a dizzy, sick at stomach sensation, like sea sickness.
Dull headache on waking.
A strange sensation in head on first lying down as if some light substance was rolling from above eyes to vertex.
Severe headache beginning upon mastoid process on left side and extending over head to opposite side.
Complete physical exhaustion without any apparent cause.
Chilly all day, although room was warm; muscles of the whole body sore to touch or pressure.
In the morning so weary and muscles ache so severely it is difficult to arise.
Great heaviness in head and pain in occiput and neck.
Severe headache, agg. on second day, lasting until the third, recurring from time to time for many weeks and compelling quiet fixedness. – Burnett.
Headache, with frequent sharp, cutting pains passing from above right eye through head to back of left ear. – Rose.
Headache of great intensity preceded by a shuddering chill passing from brain down spine, with attack a feeling as if head above eyes were swollen; became unconscious with screaming, tearing her hair, beating her head with her fists or trying to dash it against wall or floor. – Swan.
Headache of forty-five years standing, pain passing from right frontal protuberance to right occipital region. – Swan.
Terrible pain in head, as if he had a tight hoop of iron around it; trembling of hands; distressing sensation of damp clothes on his spine; almost absolute sleeplessness; profound adynamia; was thought by his friends to be on verge of insanity; most of his brothers and sisters had died of water on brain; right lung solid, probably from healed-up cavities, as he at one time suffered from pulmonary phthisis. – Burnett.
Sullen, taciturn, irritable, screams in his sleep, is very restless at night, constipated; sister died of tubercular meningitis. – Burnett.
Fretful and ailing, whines and complains, indurated glands can be felt everywhere, child hot, drowsy, urine red and sandy, much given to be frightened, particularly by dogs; was vaccinated and had a very bad arm for four months thereafter; would not smile, whimpers when spoken to skin dingy, skull hydrocephalic. Burnett.
Boy, aged 20 months, ill for days with head, high fever, restlessness and constant screaming; finally no sleep for forty hours, followed by a condition of collapse; peculiar smell of body, family history of tuberculosis. – Burnett.
Tubercular meningitis, with effusion; head gradually enlarged; alternately wakeful and delirious at night, talked nonsense by day, at intervals; nocturnal hallucinations and fright, delirium; pyrexia; had eczema which almost disappeared after two unsuccessful vaccinations, and which were soon followed by above condition; after administration of remedy there occurred a severe pustular eruption, then patches of a lepra and eczema appeared.
Basilar meningitis. – Sinker.
Tubercular meningitis. – Sinker.
Acute cerebral meningitis, with intense strabismus. – Biegler. Plica polonica: several bad cases permanently cured with Tuberculinum. – Jackson.
Swollen lids; headache with swollen lids in morning.
Right eye much swollen, conjunctiva inflamed.
Dullness and heaviness of eyes; darkness before eyes.
Obstruction of vision with vertigo.
Opens right eye (which had been closed.) Breaking down of cicatrices of old corneal ulcers (Stoker).
Clearing of corneal opacity the result of old tuberculous corneitis (Stoker).
Tuberculosis of eyelids, small grey and yellow nodules, existing in conjunctiva of outer sections of lids, increased in size, ran together, then suddenly disappeared.
Phlyctenulae appeared where none existed before (Maschke).
Conjunctivitis; herpes on lids.
Amblyopia with irregularity and complete paralysis of pupils ( in an alcoholic).
Stye appeared on upper lid of right eye. Lid swollen, intensely painful; four days later opened discharging green pus.
Stye on lower lid of right eye, appeared suddenly, began to swell like a bee sting. Opened within 48 hours discharging green pus.
Rushing in ears with heavy head.
Sticking pain from pharynx to ears.
Headache with rushing in ears and pressure on vertex.
Great aching in ears and teeth.
Discharge of yellowish matter from the ears.
Swelling of the glands around the ear and on the neck, worse below the ear and behind.
Slight discharge of yellowish matter from right ear.
Earl, aged 2 years. Light complexion.
January 25, 1895. Consumption on the father’s side. Since last February has had a discharge from the ears of a yellowish matter without special indications. Was relieved by some medication until within the last two or three weeks.
Now there is considerable swelling of the glands around the ear and on the neck, worse below the ear and behind, with a slight discharge of yellowish matter from the right ear. No pain. No appetite; will only take milk when it has tea in it. Not in poor flesh, but thinner than usual. Desires fresh air and wants to be out of doors. Fretful at night; seems to be better during the day. Was very feverish a day or so before the ear commenced to run. Tuberculinum 50M., one dose.
February 7. The swelling about the ear increased till Sunday night (three days) and looked as though it would break on the outside. Since then it has been going down; his ear quit running yesterday. The discharge became thick and would not run; they kept it syringed out with warm water and soap; it gradually grew less. Hardly any odor about the discharge. Stool once or twice a day. Appetite better. A little more restless at night. Anxious to get out of doors, but cried to get back into the house again. Head seems to hurt when he cries. Disposition better; he is not so cross. The swelling about the glands almost gone. Seems to be gradually improving. Placebo.
February 26. Better in every way. No swelling or running at the ear. The family consider him well. The only thing noticeable is that he seems somewhat pale and nervous when first getting up in the morning, but this soon wears of. Is in better flesh. Sac. lac. The case required no more medicine and rapidly went on to a cure.
Secretion of mucus from nose, viscid, yellow-green.
Increased secretion of mucus, with frontal headache.
Aching of ears and teeth with coryza in evening, with headache.
Bleeding of nose.
Comedones on nose, surrounded with minute pustules.
The nose, which used to feel ” hot and burning, ” has lost this sensation.
Profuse discharge of blood mixed with mucus from nares.
Seem to have a fresh cold with each change of weather.
Blowing blood from nose constantly. Profuse discharge of bloody mucus.
Small boil at end of nose; at upper nasal commissure, and one on upper lip. The boils were small, dark-red in color and contained green pus. Very slow in healing.
Sneezing, burning, watery coryza. Seemed to have fresh cold all the time.
Discharge of thick tenacious, gray-colored mucus.
Awakened every morning at 5 A.M. to clear nose and throat.
Rattling of mucus in throat immediately after eating, which must be expectorated.
Soreness inside of nose, commencing as watery pimples, which, suppurating, form scabs; nose and lips somewhat swollen; itching slightly. – Rose.
Edematous, pale face.
Clonic convulsions of musculus orbicularis inferior, acute.
Convulsions in region of facial muscle, esp. buccinator.
In one case the inflammation of the lupus (on face) presented unquestionable erysipelas of a rather severe type, and the patient was for some time in danger.
Flushing of cheek of same side as lung affected, during the reaction (Borgherini).
Upper lip and nose became swollen during the first two or three reactions, the lip becoming cracked on inner surface.
Herpes on lips and eyelids (Heilferich).
After the tenth injection his left moustache, which was kept cut to prevent scabs from gathering ceased to grow, every hair fell out, and for a month the left upper lip was perfectly denuded of hair, and had all the appearance when seen under a lens of being dilapidated; however, the hairs began to grow well before he left the Home. (Hine).
Slight swelling and itching of lips. – Rose.
Tongue foul, furred.
Tongue much coated.
Coating on soft palate and tongue.
Taste: salty, purulent.
Aphthae on tongue and buccal mucosa.
Dryness of lips.
On lips black blisters.
Palate: granulations enormously swollen and vascular.
Spit up blood streaked mucus from mouth and throat.
A bitter, disagreeable taste; nothing tasted natural. This continued for more than a month.
Tongue coated white at back and through the center.
Scalded sensation on tongue and in mouth as though burned; tongue sore at tip.
Lips dry, chapped; entire mouth very dry, but no thirst, worse in morning on rising.
Thirst for small quantities of water.
Wakened several times in the night on account of dryness of mouth.
Teeth felt loose. “Feeling as if the teeth were all jammed together and too many for his head.”
Sordes on teeth.
Inflammation of gums, scurvy-like.
Gums turgescent, felt swollen.
Aching in pharynx and larynx.
Scratching in pharynx.
Tickling in throat exciting cough.
Sensation of mucus in throat.
Sensation of a tumor in throat.
Dryness in throat; tonsillitis; general inflammatory condition of pharyngeal mucous membrane.
Burning pain in throat.
Sensation of constriction in throat; in larynx.
Heaviness and sensation of rattling in throat.
Aching extending from throat to ears.
Dysphagia increased; later diminished (in laryngeal phthisis).
Intense pain in nasopharynx on swallowing.
Sensation as if throat was swollen on the right side; expectorating a great deal of mucus from posterior nares, worse immediately after eating.
Needle-like pains in left side of throat agg. by swallowing.
Pains shooting to the left ear when swallowing; unable to eat solids.
Dryness of the throat and posterior nares, with a dry, tickling cough at night.
Eructations and sensation of fullness over stomach.