The following pathogenetic effects of this substance are derived from: Pfister’s “Schweizer Zeitschrift,” II., No. 2; Wibmer’s “Medicines and Poisons;” Ronander, in Heeker’s “Till. Ann.,” 1834; Sentaerner, in Buchner’s “Tox.” p. 202; Hegmanus, in Cooper’s MedorrhinumGaz.,” 1837, No. 27; Charvet.
Convulsive twitching. Violent spasmodic concussions. Subsultus- tendinum. Restlessness and sleeplessness. Diminished sensibility. Illusion of the senses. Muscular debility. Excessive exhaustion.
Warm skin. Itching of the skin, and cutaneous eruptions.
Disposition to sleep. Sopor. Restless sleep, which is frequently disturbed with frightful dreams. Headache after waking, margins around the eyes, general feeling of weakness and exhaustion.
Profuse sweat, with retention of urine. Cold sweat over the whole body. Small irregular pulse. Pulse small, intermitting. Pulse slow, large, intermitting. Imperceptible pulse. Fever, with intermittent, small, and contracted pulse.
Violent restlessness. Violent nervous irritation. Loss of consciousness. Stupor. Weakness of memory. Indescribable anguish. Apoplexy, loss of sense and consciousness, loss of mobility, with laborious snoring headache.
Vertigo. Dullness of the head. Heaviness in the head. Congestion of blood to the head. Irritation of the brain. Tightness in the head. Transitory headache.
Fullness in the orbits. Contraction or dilation of the pupils. Obscuration of sight.
Ringing, drumming, violent roaring in the ears.
Bluish, cadaverous face.
Disagreeable taste. Bitterness in the mouth. Loss of appetite.
Turns of nausea and disposition to vomit. Constant retching. Continual vomiting.
Pain in the epigastric region and in the intestinal canal, with constipation, which is frequently followed by sudden diarrhoea. Colicky pains. Suppression of stool and urine.
Constipation. Violent diarrhoea.
Ineffectual urging to urinate. Diminished and concentrated urine. The breathing. The inspirations are rare and rattling. Violent beating of the heart and carotids.