APIS-MELL Poison of the Honey Bee(See “New Materia medica”).
RATIONALE OF ITS ACTION.
Nerves of Motion. We infer that it operates as a gentle stimulant and tonic upon he anterior portion of the spinal
column,. An increase of muscle power, and a tendency to spasmodic movements of various muscles have now and then been observed from a protracted use of large doses.
Nervous of Sensation.
It rouses the nerves of sensation into a condition of morbid excitability. A marked effect produced upon several provers was excessive sensitiveness if all parts of the body to the touch, the heat, and cold;a nd their sensitiveness was usually accompanied by great mental irritability.
Many facts prove that it acts specifically upon this system of nerves. Its influence in producing muscular contractions of he uterus, miscarriages, menorrhagia,., is probably due to a primary action upon the great sympathetic. Other reflex phenomena have occasionally been noticed, which lead us to the same conclusion.
Upon the mucus membranes of the tongue, mouth, fauces, and throat it acts specifically; redness, burning sensation of fulness and dryness are the chief effects. Two proves experienced coryza. With feeling of swelling and burning of the Schneiderian membrane. It acts especially upon the neck of the bladder, producing mucus and bloody maturation. Its influence upon the pulmonary mucus membrane is evidenced by oppression of he chest, frequent inclination to expectorate, and burning of the membrane.
Its action upon the serous tissues is strongly marked. Among the first effects which e experienced while proving it, was great tenderness of the entire peritoneum on pressure, or an turning in bed. It impresses specifically all the serous membranes, producing the kind of inflammation which disposes to dropsical effusions. the physiological and clinical facts adduced farther on will demonstrate this conclusively.
Temporarily, it exalts muscular power; but a reaction occurs in a few hours, which leave the muscles wearied, weak, and tremulous. the muscles are apt to become stiff, tender upon pressure, and somewhat swollen.
Ovaries. Upon these organs it exerts most powerful influence. Not only does it produce inflammation and enlargement of the ovaries themselves but it operates specifically upon their serous envelopes.
It acts slightly upon the tonsils and the salivary glands; but this slight action may be due to the effect produced upon the mucous membrane covering these glands.
The action of Apis is very similar to that to Cantharides, Euphorbium, Mezereum and Rhus, and it often succeeds when these remedies fail. It is often wonderfully useful in erysipelatous, serous, and oedematous inflammations, and in serous effusion and dropsies; still we have often seen it fail in our own and others hands, when it seemed fully indicated. J. C. P.
In doses of five, ten, or fifteen drops, three or four times a day, it is highly recommended in may diseases for he bladder and kidneys, and well as in some uterine affections. Some practitioners assert that it will produce abortion in the pregnant female if its use be too long continued or when employed too freely. It seems to have been most successful in quinsy, ascites (particularly post-scarlatina.) amenorrhoea, dysmenorrhoea, hypertrophy of uterus, with induration,. some forms of ophthalmia, and also hordeolum or stye, erysipelas,,., have been cured. See the report above alluded to. for hydrops-amnii et oedema-labii, see Peters’ “Diseases of Married Females.” it is appropriate in scarlatina, when there are much heat, redness, and irritation of the skin, great restlessness and nervous agitation, sensitiveness of the entire surface of the body, an oedematous and erysipelatous appearance around the ulcers in the throat, frequent and painful urination, redness, heat and burning of to tongue, disturbed sleep and thirst. In many instance, s where the above group of symptoms have been prominent, the third dilution of Apis has afforded speedy relief. Its virtues in scarlatinal drops are well known. Operating, as it evident that it must prevent an excellent simile to a majority of the cases. Post-scarlatinal dropsy, in a in a girl about nine years old, developing itself a month subsequence to an attack of scarlatina, was treated successfully, by Dr. E. A. Munger, with Apis; the patient was in the following condition;Puffed face, violent beating for he heart,. distinct over the whole chest; pulse 160 or more; respiration excessively labored, panting, and hurried; inability to assume a recumbent posture; urine very scanty and high colored; heat and dryness of the surface, with thirst; no pain. Aconite, Arsenicum, Belladonna, digit., Hello., with no apparent change for the bete; on the contrary, on the second day of January, being being the third or fourth day of her present illness, the condition became still more alarming; face and lips livid; gasping and exceedingly rapid respiration;, and cold face and extremities. The case distinct;cold perspiration and cold face and extremities. The case was considered as extremely doubtful of recovery; however, after the use of Apis, 3, for about twenty four hours, the patient began to pass large quantities of urine, and from that time gradually recovered, when, on the tenth day of treatment, she was considered perfect cured.
A case of eruption was cured by Dr. Bishop, with the following characteristics: commencing with small pustular formations just Under the cuticle, with burning, smarting stinging sensation; in coming to maturity, deposition of dry scabby matter, laminated form, scaly brownish nd sometimes straw colored. looseness of the bowels in the morning, thin watery, yellowish; some griping at times, but generally painfulness. the looseness of the bowels had continued three or four weeks. Treatment for the last ten days, Rhus and other antipsoric remedies; no abatement of symptoms, either of skin or bowels. The parts mostly affected with the eruption were the inner back of the neck, and upon the central portion of the body. He was received Apis, first, to be taken twice in twentyfour hours, which was followed by an effectual and almost immediate cure of both diarrhoea and eruption; no return for eighteen months.
The cutaneous affections or which Apis is most appropriate are urticaria, lichen, porrigo, eczema, prurigo, and certain forms of scarlatina. The special indications are, itching, stinging, pricking, and burning of the eruptions. When the eruption presents this peculiarity, and other symptoms correspond, one of the high dilutions will generally afford prompt relief. Dr. E.A. Munger has used Apis mellifica with success in several cases of Urticaria, of which the following are the most prominent symptoms: Hard, red, somewhat conical swellings, occurring usually on the lower extremity, s below the knees, but sometimes on the arms, and occasionally, but rarely, on other parts of the body, varying in number and size, some being no larger that a halfdime, others an inch or two in diameter. Heat, redness, extreme soreness, and a burning, smarting, stinging pain are the principal characteristic symptoms. In from two to six days the spots which made their appearance become livid, and the swellings heat, and pain subside but, unless the disease is checked, new ones continue to appear for an indefinite time. There is usually but slight general swellings of the limbs affected, and but little febrile excitement or other constitutional symptoms; but, in a few instances, they have been considerable. The accumulation of evidence of its efficacy in ascites and anasarca is too voluminous for a work of this nature; suffice it to say that it is among the most prominent and certain of its therapeutic properties.
MIND AND DISPOSITION.
Irritable disposition the whole day;nothing appeared to satisfy him, everything awry. Unfitness for mental exertion. Dread of death, or sensation as if the should not be able to breath again Great anxiety, and apprehension of some approaching disaster. Intellect clear and active, but morose and irritable.
Confused vertigo for several days, at time very violent, worse when sitting that when walking, and extreme then lying down, and closing the eyes, from several doses of he thirtieth. Head is dull and slightly confused Crazy, wild, blind staggers in horses (old observations). Vertigo on riding suddenly from bed Lightness of the head on rising, and when walking in the open air.
Chronic headache in nervous subjects; violent pain in the forehead and temples, at times involving the eyes, attended by vertigo, nausea, and vomiting must hold the head and eyes down Pain in h sinciput, and confusion of the head. Violent headache, mostly confined to the forehead, with fever, second day Burning and throbbing in. The head aggravated by motion or stooping, temporarily relieved by pressing the head firmly with the hands, with occasional sweat for some hours. Violent pressive pains in the forehead and temples for several days. Violent sharp pain in the left temple. Headache, e with fullness and heaviness in the occiput. Sense of fullness and heaviness of the head. Head feels as if swollen. Severe pains in the eyeballs, increased by exposure to light. Puffiness of the scalp, forehead and around the eyes.Integuments of the head feel swollen and stiff.
Night sleep is full of dreams (this symptom repeated in every proving).Fidgety restlessness the latter part of the night. Fidgety restlessness the entire night, with inability to sleep._Greet inclination to sleep, but inability to do so, from extreme restlessness and nervousness. Sleep disturbed by
oppressed respiration and disagreeable dreams. Sudden starting from sleep, with great agitation and anxiety the prover wakes from sleep in the morning. weary and unrefreshed.
Quivering and twitching of the left eyeball, especially at night Burning stinging in the right eye, commencing with a dull heaviness, causing flow of water;twice repeated Stinging itching in the eye, eyelids, and around the eyes. Pain around the or nots of the eyes. Slight agglutination of the eyes at night;had to pick them open in the morning. Soreness, redness of the eyes and lids, secretion of mucus, and agglutination of the lids, attended with nettle rash over the surface. Erysipelatous inflammation of the eyelids. Weak eyes; for several days, with photophobia. Oedematous swelling of the eyelids. Smoky opacity of the cornea,. occasioning almost entire loss of sight curative) Redness and smarting of the eyelids, eyes sensitive to light. Puffy swellings of the eye lids, and around the eyes, with sensation of burning, and stiffness of the integuments. Acute pain in the eyeballs, slight inflammation of the lachrymal sac. Redness of the conjunctiva, with burning pain, increased flow of tears, and great sensitiveness to light.
Sneezing Redness and burning in the nostrils. OEdematous swelling of the upper lip and nose. Erysipelatous Inflammation swelling of the nose. Acrid discharge from the nostrils Burning, itching and stinging eruption upon the nose.
Jumping pain in the superior molars of the left side. Sore pain in the several teeth, accompanied by swelling and redness of the gums and cheeks. Throbbing pain in a single tooth, with numb sensation in the gums.
Sore elevations, like the sting of insects, very tender to the touch, at the external corner of the eyebrow. Burning stinging, as of fire, on the chin, malar bones, and left superciliary ridge. swelling of he lips, and sensation of swelling for several days, followed by a fine eruption around the lips, and dryness and peeling off the lower one, pricking in the lips, a sensation as if they had received a severe contusion, with sensation of welling in the few hours. Face puffy, with a feeling of stiffness Face swollen, red, and painful, lips swollen, stiff, and slightly tender.Puffy swelling (oedematous) under the eyes, with smarting and burning of the eyelids Itching and burning
eruption upon the lips, the chin, the nose, and under the eyebrows. Spots like hives upon the chin and cheeks.
MOUTH AND THROAT.
Contraction and erosion in the throat in the morning.Extreme sensation of rawness and scalding all around the margin of the tongue, as if it had been scalded, and slight pimples on the edge,, from taking the tincture at four hours. Increased feeling of contraction in the throat, rendering deglutition difficult, Scalding of the mouth and throat for two days Dryness if burnt Dryness of the tongue; red, fiery appearance of the buccal cavity, with painful tenderness.an aching pressure, as if from a hard body, back in the upper part of the throat and fauces Stinging burning, dryness, and swelling in the throat. Frequent inclination to swallow, but the act is attended with some difficulty, from diminished power over the muscles of deglutition )Dryness of the tongue, with prickling sensation in. he tongue and fauces Edges, swelling, swelling, and burning pain of the entire tongue Erysipelatous appearance of he tonsils and fauces.
APPETITE AND STOMACH.
Violent eructations Nausea, apparently from the throat Nausea and inclination to vomit at night, and disagreeable rumbling in the abdomen, as if diarrhoea would come on. Pricking pain, and sensation of heat and burning in the stomach. Increase of appetite Strong craving for food and drinks, but nausea eructations, heat, and burning in the stomach shortly after eating or drinking Distention of the stomach, with occasional burning sensations at the pit of the stomach and in the throat, lasting several days, and followed with catarrh of the catarrh of the stomach, with its usual dyspeptic concomitants Bitter, or acrid eructations.
Abdomen full, swollen, and tender, with swollen feet and scanty secretion of urine Burning, internal soreness, external tenderness, even to the pressure for the bedclothes. Aching and pressing pain in the hypogastrium, with bearing down in the uterus, as if the menses would come only in two persons.Rumbling in the abdomen, as if diarrhoea would ensue Sore, sickly feeling in the abdomen Dull pain in the bowels Fullness and evident enlargement of the abdomen, men from, many and large doses, in a female. Fullness and sensation of bloating in the abdomen Tenderness of the entire abdomen on pressure, or on turning in bed Sensation of fullness, with dull pains, high are worse on motion, or from pressure Tension over the hypochondriac region, with pricking sensations.
ANUS AND STOOL.
Throbbing in the rectum. Loose, lumpy stool. Loose, urgent stool in the morning. Stools soft and pappy, mixed with serum. Loose stools, eight days in succession. Several loose yellow stools., with extreme weakness and prostration; stools committing own at every movement of the body, as thought the anus were continually open, in a lady of forty, affected with chronic ascites.
Yellow, watery diarrhoea;; griping; twelve movements in as many hours; frequent yellow watery evacuations, from a single dose Watery diarrhoea, the smarting at the anus. Frequent disposition to go to stool, with inability to accomplish anything. Distention and soreness of the bowels, with much flatulency, and small brown alvine discharges, affording no relief Small bilious discharges which produce slight smarting at the anus Frequent disposition to go to stool, with inability to accomplish anything Distention and soreness of the bowels, with much flatulency, and small brown alvine discharges, affording no relief Small bilious discharges, which produce slight smarting at the anus and tenesmus. Loose discharges. Containing some mucus and considerable blood.
URINE AND GENITALS.
Repeated urination every few minutes, continuing through the entire day, in a person never subject to such attacks. Frequent and excessively profuse discharge of natural urine through the day and night, in a dropsical and pregnant subject, from three doses of the thirtieth Frequent and copious discharge of urine Burning in the urethra, before and after micturition pustule, sore as a boil, surrounded by a red areola, and maturated in the centre, arises in the hair of the pubes,. remaining sore and painful some days Frequent desire to urinate, attended with burning in the urethra, with uneasiness in the spermatic cord; on the sixth day, from large doses Frequent urging to urinate with copious discharge of strawcoloured urine from large doses) Vesical tenesmus, with frequent slight discharge of red urine Burning and scalding in the urethra, especially near the neck of the bladder during and after urination Frequent and painful urging to urinate, with scanty discharges of urine, mixed with blood. Copious urinary secretion (primary effect), succeeded by every rare and small discharges (secondary effect)After urination, pain in the neck of the bladder, with shooting pains along the ureters towards the kidneys.
Bearing down pain, and sensation as if the menses would come on in many cases. Bearing down pains in the uterus, as if the menses would come on, with aching and pressing in the hypogastrium Metrorrhagia at the second mouth, with profuse flow of the blood;heaviness of the abdomen; faintness;great uneasiness; restlessness, and yawning. Haemorrhage from the uterus, occurring in a lady who was always regular and healthy;occurring one week after taking the medicine Miscarriages at the second, third, and fourth months. Suppressed menstruation (Pathogenetic and curative effect in many ovaries, with ocassional bearing down sensations in the ovarian and uterine organs. Sharp, cutting pains in the left ovary worse at intervals, and extending down the thigh. Severe paroxysms of contractive and spasmodic pain in the right ovary, occurring ever fifteen to twenty minutes and each paroxysm lasting from one to three minutes. Six days previous to the monthly sickness, sensation of weight and heaviness in the ovaries; pressing pains at the as-uteri, and after taking the second dilution, night and morning for three days, premature appearance of the menses, with unusually copious flow Great tenderness over the uterine region, with bearing down pains, leucorrhoea, and painful urination after four doses of the tincture. Profuse yellow leucorrhoeal discharge. Green and acrid leucorrhoea, with frequent and painful urination. Conversion of an existing mild leucorrhoea to one of a yellow and irritating character.
LARYNX AND TRACHEA.
Hoarseness and rough voice, day and night, on second day. Heat and smarting in the throat, with occasional hacking coughs. Dryness of the throat in the morning, causing cough and hoarseness. Hoarse voice and hoarse cough, from irritation of the trachea. Hoarseness, with scraping in the larynx and oppression of breathing. Symptoms worse in a worse in a warm room, and ameliorated in the open air.
Stitches in the left side of the chest. sensation of aching heat in the region of the diaphragm, as if from running violently Pressure in the chest, soon. Sharp pains and stitches though the chest and back at night Hurried and difficult respiration, with fever and headache. Pain near the heart, almost arresting breathing at night, continuing at intervals for some days. Short, rapid breathing at night. Sensation of soreness, lame, bruised feeling, as if from a recent injury, from being jammed, bruised, or beaten; confirmed in many provers. Sensation of burning heat in the chest and stomach, early in the morning, second day. Sense of fullness, constriction, or of suffocation in the thorax; difficult and anxious respiration, aggravated by lying down, and ameliorated by inhaling the fresh air in an up right posture Burning and stinging pains throughout the entire front part of the chest. Slight pleuritic stitches in the sides of the chest.
Rheumatic stitches in the muscles of the right side of the neck, worse on motion. Tension in the right side of the neck, beneath and back of the ear. Sudden flush of heat over the back, as though sweat would break out, accompanied by a pain at the left ileo sacral articulation, Dull pressure under the scapulae, with sore feeling on motion Pain in the back, under the scapula, worse on moving.Stiffness in the small of the back Weakness of the back Weakness of the back, obliging him to lie down Stiff and weary feeling in the lumbar muscles. Itching eruption like urticaria covering the entire back, and extending up the back of the neck to the hairy scalp.
Blotches on the neck and back, which itch and smart on rubbing and scratching them. Pain and soreness in the region of the kidneys, on pressure, or on stooping, constant dull pains in both kidneys, with small secretion of red urine (from repeated doses of the twelfth dilution).
Fiery burning at the points of the fingers of the left hand. Dull pains, apparently in the bones of the arms and fingers of the left hand Dull pains, apparently in the bones of the arms and fingers. Aching in the right shoulder and upper portion of the arm Red spots the arms, hands, and fingers, which itch and burn very much. OEdematous appearance of the hands and fingers. Feeling of stiffness in the hands and arms.
Fine burning stinging on the knee. (OEdematous swelling of the extremities. Darting, transient pain in the external malleolus of the left ankle for four days. Dull pains, as if in the bones of the lower extremities, disappearing on walking, returning again while sitting. Burning of the toes, and redness like erysipelas, and heat of a circumscribed patch on the foot, while the remainder of the foot is cold continuing half an hour. At night, the feet were found swollen, with a sensation of heaviness and rigidity; the upper part of the feet felt tingling and itched, and were of a bright red color. The soles of the feet and balls of the toes had a feeling of painful fullness, and in walking gave a sensation as if cushioned; sixth day, from large doses(OEdematous swelling of the legs and feet, with sensation of weariness and stiffness when posterior portion of both thighs Bruised and sore feeling in the feet.