(On the 15th of June I began a proving with Salicylic Acid. Not venturing to expose myself to any very serious action of the drug, having had a sufficiently troublesome experience of its power in the 10the potency, I only took a small part of a drop of the 30th, repeating the dose four times at intervals of about two hours. Here are the results which I observed for twenty-five days after, when I started on a vacation trip, from which I did not return until Friday, July 22)
First day: 2-30. P.M. About fifteen minutes after the first dose a burning and scratchy feeling on the tongue. Drawing pain in the calf of the left leg, extending up into the thigh, and then transferred to the left arm. Later, a similar pain for a short time back of the right temple.
4-30 P.M.-Nervous excitement after gentle exercise or walking.
6-30 P.M. Pain in the knuckles of the right had.
6-45 P.M. Third dose.
8-45 P.M. Forth dose. During the night, pain on the top of the head, in one spot, as if struck by hammer.
Second day.- Swelling under the skin of fingers on both hands; with a burning itching on the inside of the left hand. Itching on the back, below the jaw-bones, and under the chin. The rheumatic pains feel worse when walking outdoors.
Third day. – After a good night’s rest, awake dull and nervous, with a ringing in the ears, especially the left, and a fulness in the head. Dizziness. Pain in the bones below the left eye, as if bruised. Rheumatic pains in the upper and lower extremities continue. Nervous headache characterized by a bruised feeling in the head (not aggravated by exposure to a very hot Sun). General lassitude and weakness, worse indoors, relieved in the open air. Stoppage of the ears, especially of the left. Much sexual excitement.
Forth day.-Dull headache on the left side of the head. Feel very uncomfortable and indisposed to any exertion, mental or physical. Difficulty in voiding urine-it flows slowly and seems less in quantity. Pain in the sinews of the left forearm, extending into the third and little fingers, followed by a tingling sensation. Pain in the left inferior maxillary bone; the parotid gland is painful when touched by the finger, affecting the inside of the throat. Burning pain inside the joint of the thumb. Scratching sensation in the left side of the throat. After lying down in the afternoon stiffness and aching in the muscles of the back along the spinal column. The morning headache, better during the day, is aggravated in the evening. Palpitation of the heart. During the night following an unconscious, profuse and somewhat bloody discharge of semen (or prostatic fluid) staining the linen a brownish color, and followed on awaking, by a a pain in the genitals, as if over-strained.
Fifth day.- Headache, continuing during the night, better in the morning. Tedious and insufficient stool. Headache returns in the after noon on the right side. Pressive pain in the forehead, above the right eye. Itching of the left upper eyelid. Itching of the skin after undressing; better in bed. Sexual excitement, more physical than mental. Very restless at night, longing to sleep, with inability to do so.
Sixth day.- During the night, rheumatic pains in the lower limbs and feet. A kind of burning sensation in the ball of the great toe. On awaking in the morning, pain in the right shoulder, as if from a strain, continuing some hours. Still some headache with a dull, bruised feeling in the right side of the head. During the day all symptoms disappear, returning again in the evening. Itching of the head, with feeling as if the hair stood on end.
Seventh day.- Awake during the night, with stiffness in the back so as only to be able to turn with difficulty. Severe pressing pain in the lower abdomen and bladder, without urging to urinate, and only small discharge. In the morning, stoppage of the ears returns. In the afternoon a sharp, stinging pain in one of the toes of the right foot. In the evening, sore feeling on both sides of the lower jaw, under the tongue.
Ninth day.- The rheumatic pains and headaches have disappeared. Itching pimples here and there on the body; one on the right cheek.
Tenth day.- The eruption continues. After removing some ear wax from the left ear, pain and feeling of stoppage.
Eleventh Day. Stoppage in both ears, early in bed and after rising. Eruption continues, red pimples here and there; and small whitish ones, the latter in groups itching and filled with water. In the evening, feeling as if I had taken a long walk.