Mr. R., young man, 38 years old, was discharged from the U. S. army for physical disability from chronic malaria; had taken quinine in twenty grain doses for years to keep down recurrent malaria; he seldom went longer than six weeks before his chills would return; he suffered severely, but with a confused general condition. He had never permitted his case to develop into well defined symptoms but he was pale and ached all over; full of chilliness in the afternoon and evening and heat all night. Chronic indigestion; can eat but few simple foods. Malaria contracted in Delaware over twelve years ago; has suffered ever since. Distended with much gas stomach and bowels. Burning pain. Restless during fever and must move constantly. Aching in limbs with fever. More sensitive to cold than to heat; likes to be warm. Cannot concentrate mind. Thirst only moderate. Wants everything very salty. Stool: urging drives him out of bed every morning. Feet are so warm that he sleeps with there out of bed often in cold weather. Sulph. 10m relieved all his symptoms and he felt well for six weeks, then his symptoms began to return; he had been thinking he was well. Sulph. 10m was repeated and he did not return for 40 days because he thought he could do without me, he felt so well. His symptoms began to return; Sulph. 50m. Has remained in perfect health. He is an engineer and much exposed, but his endurance is better that it ever was and he has added flesh and colour.