After continuing about two hours, the dryness of the mouth is suddenly relieved by the appearance of a viscid acid secretion of an offensive odor, like the sweat of the feet.
The mouth becomes foul and clammy, and a bitter coppery taste is complained of.
Excessive secretion of saliva (second day).
Everything tastes salt (after one hour).
Same slimy taste in the mouth (after three hours).
Slight sweetish taste in the mouth.
Food all tastes alike, like sawdust; tastes dry and cannot be swallowed except by washing it down with some liquid, owing to the deficiency of secretion of saliva (after two hours).
Food is tasteless (after half an hour). difficult speech.
Speech thick, probably from dryness of the mouth and throat.
After many days’ action of Atropia, there manifested itself a slowness and embarrassment of articulation of words.
Frequent stuttering, especially at words difficult to pronounce (never used to do so), (sixth day).
Articulation indistinct, rapid, and chattering.
Throat.
Slight throbbing or heaving sensation in the carotids.
Mucous membrane of the throat slightly darker than in health, and presents a mottled appearance (second day).
Constant choking in the throat, which was soon followed by an almost complete inability to swallow, with a feeling as if seized by the throat.
In a few minutes a feeling of dryness in the throat, causing constant inclination to cough.
On the third day he complained of sore throat, and inability to pass his water.
Intense feeling of dryness in the throat, which abated toward morning.
Shortly after taking the drug, a sensation of dryness in the throat Dryness of the throat and feeling of pressure in the anterior and superior cerebral regions.
Great dryness of throat and mouth (twenty to forty minutes).
Violent burning in throat.
Burning in throat and stomach.
Slight feeling of fullness in the throat (after half an hour).
Soreness of throat increasing till quite hoarse (after eleven hours). Throat has been quite sore for the past six hours; pain upon swallowing (second day).
Throat feels raw and irritated (second day).
Throat feels raw and sore (after seven hours).
Drops of white mucus sticking to the uvula (after ten minutes).
Fauces and uvula red (after ten minutes).
Slight dryness of the fauces.
Dryness of the fauces (in two hours).
Feeling of dryness in the throat, causing constant inclination to cough; swallowing water affords relief.
Swallowing difficult, but not impossible.
Feeling in mouth and throat made her think she “could not swallow,” but when impressed with the necessity of so doing, she drank with avidity the warm water offered, though at first it seemed quite difficult.
Swallowing appeared to give pain, manifested by grimaces and increased spasms of the facial muscles.
There was great difficulty in getting the child to swallow, each attempt to do so producing paroxysms of suffocation, which appeared to threaten his existence.
Difficult deglutition, every attempt to swallow caused suffocation.
Dysphagia, parallel with the dryness of the fauces.
Difficulty in swallowing on account of dryness of the throat.
Stomach.
With constant hunger, was soon satisfied, the food seemed tasteless. Increased desire for salt food (anchovies, herrings, smoked meats, etc)..
Ate a light a supper, having to wash the food down with water (after seven hours).
Aversion to meat and beer; beer increased the empty feeling in the stomach and caused a painful pressure; this aversion to beer and the unpleasant symptoms caused by it continued through the whole proving.
Appetite wanting (second day).
Loss of appetite (becomes after the drug-influence violent hunger).
No thirst, in spite of the dryness of the throat.
Thirst moderate (second day).
Frequently asks for water to drink.
Thirst greatly increased, threefold.
Frequent empty eructations without relief.
He had eructations tasting like the yolk of eggs, at intervals through the day (after ten hours).
Nausea (after quarter of an hour).
Slight nausea (after one hour). slight nausea (after ten minutes).
Slight nausea, lasting but a few minutes; these coming on again after an interval of half an hour (first day).
Nausea, and transient inclination to vomit.
Fruitless vomiting of colorless mucus, and afterward of green bitter fluid after the morning vertigo.
Vomiting, readily induced by drinking warm fluids (after two and a half hours).
Vomiting after drinking milk.
Hurried from bed and vomited profusely; easy vomiting of a watery fluid, tasting bitter at first, nearly tasteless afterwards: during the vomiting, very severe sticking pains in the umbilical region; vomited about five minutes, and then staggered back to bed (after eleven hours).
Great distress in the epigastrium, which seemed indescribable.
Uncomfortable sensation in stomach (in fifteen minutes).
Uneasy sensation in the stomach, accompanied by frequent empty eructations, affording no relief. The uneasiness, which gradually became associated with nausea and retching, increased to a pressing, sticking, and contractive pain, accompanied with frequent empty eructations.
This spasm of the stomach, which was attended with paleness of the face, slight perspiration, singing in the ears, and an aching pain in the forehead, lasted two hours.
Beer caused a constrictive pain in the stomach like a stomach cramp, which obliged him to sit down, was increased by walking; with copious eructations of air; though this pain steadily increased it completely disappeared after three hours.
Some sensitiveness to very strong pressure in gastric region (after fourteen hours).
Much relief after vomiting, produced by copious draughts of warm water.
Abdomen.
Abdomen a little tense (after fourteen hours).
Abdomen swollen and tense, but not tympanitic; upon pretty firm pressure upon it, patient gave signs of suffering.
Stool and Anus.
Paralysis of the sphincters of the rectum and bladder.
Paralysis of sphincter ani with involuntary fecal discharges (in three patients, from 1 1/2 grain and upwards).
Hurried from bed urgent desire to stool, followed by very copious watery stool coming with a gush.
This stool relieved the pain in the umbilical region (after thirteen hours).
Another copious stool (after fourteen hours).
Arose and immediately had another copious, watery stool; (second day).
During stool, felt badly generally, weak and terribly nervous, with general perspiration.
In the stool, thin fluid seemed to be mixed with urine (after three hours).
Stool, only two to four days (in health, daily).
No evacuation for five days, and then only induced artificially.
Urinary Organs.
Tenesmus and frequent desire to pass urine (after four and a half hours).
Frequent desire to micturate, passing only a moderate quantity of urine.
Constant and frequent desire to pass water, but inability to do so.
Incontinence of urine, and involuntary fecal discharges.
Urine profuse; first at 6 P.M. (after twelve hours).
Has had profuse urination for the past twenty-four hours (second day).
Urine passed slowly and increased in quantity (after three hours).
Frequent micturition at night.
On the night of the first day, between 10 and 1 o’clock, was compelled to urinate as often as ten or fifteen minutes, without pain.
The quantity voided was profuse and almost colorless.
Urine and thirst increased.
Urine not increased, notwithstanding the dryness of the skin.
Passed very little urine.
On the fourth day he passed his water in drops and with great difficulty.
Catheterism was required during the next four days.
Dysuria, or more or less complete retention of urine for two or three hours, or longer, invariably follows the action of a full medicinal dose of the drug.
No urine for nine hours (first day).
No urine passed for thirteen hours.
He had passed no water since the preceding evening; bladder not distended.
Urine clear and corresponded in amount to the water drank (increased).
Urine acid, dark, brownish, without sediment, and containing Atropine.
Respiratory Apparatus.
Dry tickling cough, periodic, with a sore feeling in the throat and pressure on the chest; excited by speaking or smoking.
Has had several paroxysms of coughing, caused by the collection of mucus in the throat, occurring once in fifteen or thirty minutes, attended with the difficult expectoration of a thick, tough mucus; after coughing, burning in the throat (second day).
Small quantity of thick, frothy, white sputa is ejected at intervals (after ten minutes).
Huskiness of voice (twenty to forty minutes).
She tried to call out but her voice refused her.
The voice is sometimes weakened, or there may be complete aphonia.
Sensation of choking in an hour after the first application.
Respiration 28.
Chest.
Feeling of warmth as of a glow through the thoracic region (after half an hour).
Heart and pulse.
Heart’s action irregular and apparently obstructed.
Weak doses accelerated the heart and increase blood pressure; poisonous doses have the reverse effect.
Distressing fluttering sensation in the cardiac region.
Pulse of fair fullness and strength.
Pulse very weak (after two hours).
After ten or fifteen minutes, an acceleration of the pulse from 20 to 70 beats; no apparent change in volume, but a decided increase in the force of the cardiac contractions and of the arterial tone.
Born in 1837in Westminster, Vermont. . He was an orthodox doctor who converted to homeopathy
Dr. Allen compiled the Encyclopedia of Pure Materia Medica over the course of 10 years.
In 1881 Allen published A Critical Revision of the Encyclopedia of Pure Materia Medica.