Leloir so named a condition in which the lesion is usually single, rarely multiple, and typically appears on the back of the hands and on the buttocks although it may occurs elsewhere.
The ordinary acute type, running a course of a few weeks, ends with little or no scarring. It commences as a round or oval, moderate elevation, reddish-purple or bluish in color, 1/2 to 2 inches in diameter. The surface may be smooth, scaly or crusted with a number of pin-head-sized openings from which pus can be pressed out. A large number of yellowish-white dots indicate the sites of the same condition in the process of formation.
A more pronounced form, resembling carbuncle with moderate fluctuation but no constitutional symptoms, adenitis or neurotic core formation, has been described. Brownish pigmentation may remain for some time after the evidences of the disease have disappeared. Sycosis-form, carbuncular, phlegmonous or, rarely, papillomatous variations, that may develop and thereby change the course of the disease, are not uncommon.
Etiology and Pathology. Contagion from the staphylococcus pyogenes albus is believed to be the active cause and those who work among animals, especially horses, seem to be more prone to it. The process is a suppurative perifolliculitis of both the hair-follicles and the sebaceous glands occasionally involving other structures and assuming a likeness to other diseases.
Prognosis and Treatment. This condition may be persistent but usually responds to suitable treatment. The latter consists of cleanliness and the application of a mild antiseptic ointment of boric or salicylic acid or lotions of formalin (10 per cent. in water), creolin (2 per cent. in glycerin), succus calendula (10 per cent. in glycerin) and the administration of a remedy to control suppuration. See indications for Calcarea sulph., Hepar, Kali brom., and Petroleum.