Pollitzer and Janovsky have described a condition characterized by more or less generalized, pigmented and warty growths. About forty of these cases have been reported in which there was a strong resemblance to ichthyosis, verruca or nevus pigmentosus. The face, neck, abdomen, back of hands and the flexures are the seats of the yellowish-brown or blackish discoloration. As these regions become thickened, the natural furrows are exaggerated and discrete or closely aggregated warty growths appear. The mucous membrane of the mouth may become involved, in which case the tissues present a papillomatous aspect.
Etiology and Pathology. – This is a condition of adult life, rather more common in women than in men and depends to a marked degree on carcinoma of the abdominal viscera.
Prognosis and Treatment. – A fatal termination may be expected in most cases. Treatment is unsatisfactory. Locally such measures as are noted for nevus pigmentosus may be used if feasible. Suprarenal extract has been administered, and Thuja and Aurum mur. present similar symptoms.