1. Dark, sallow, spare subjects of passionate temperament; sedentary brain workers; chronic dyspeptics addicted to stimulants; victims of drug habits, drastic medicines, excesses, etc.
2. Hypochondriasis with irascibility and impatience; spiteful and malicious or sullen and surly, thinks everyone is against him; melancholy (>) alone esp. from relatives; “spasmodic” homicidal or suicidal impulses; precise, ardent but overbearing, dread of, and incapacity for literary work.
3. Mental and physical hypersensitiveness (even fainting to external stimuli; also to pain, trifling ailments, etc.
4. Gastric disorders from atony; hunger yet no desire for food; distension and discomfort an hour or so after meals with nausea; taste, eructations, vomit, etc., all sour or bitter; “if only could vomit would be better”; assoc. “bilious” morning headaches; craving for condiments and sour or bitter things; likes fat.
5. Habitual constipation; frequent but ineffectual desire for stool, or small quantities passed at each attempt (from spasmodic peristalsis); blind or bleeding piles; stool temporarily (>).
6. M.P. premature, profuse, protracted with bearing-down pains, nausea in a.m., chilliness and attacks of faintness.
7. Drowsiness during evening, wakeful at 3-4 a.m., but later falls into heavy, unrefreshing sleep; awakes late tired and worn out. Always. (>) undisturbed sleep.
8. Convulsions with consciousness; tetanic rigidity (<) external stimuli esp. touch; also violent local muscular contractions.
9. In fevers patient must be covered in every state-chill, heat and sweat; cannot move or uncover without being chilly.
10. Patient very chilly, (<) winter, open air and draughts; dry weather; mental exertion; anger; morning after eating; (>) warmth; mild, damp weather.
Notes. Nux acts best during repose of mind and body; dose a few hours before retiring. Sepia its chronic. Zinc is inimical. Keynote-Irritable tension.