Adenocarcinoma with Hurthle cell change are relatively rare lesions. They behave like adenomas or adenocarcinomes. The cells of these tumors bears a close resemblance to those of the liver and the adrenal cortex. They are compactly arranged to form small alveoli. The tumor may be discrete and well encapsulated or diffuse and invasive.
In most of these cases there already has been nerve involvement caused by the encroachment on the surrounding structures and it is here that we run into recurrent nerve paralysis. There is practically no tendency for this disease to recur after thyroidectomy. However, following operation, myxedema is very apt to occur and of occur the patient must then be kept on thyroid hormone.