5 b. Dr. SEIDEL (no information). Immediately disagreeable coolness in throat. After 1 hours pinching under scrob. cordis, with nausea and eructation. – 1st d. Drawing in teeth. Boring in tip of tongue, its papillae elevated. Scraping in throat causing him to cough frequently, e. A pappy stool with pinching in abdomen and burning in anus. Urine increased. Seminal emission, n. – 2nd d. Violent burning, drawing pains in renal region, lasting 5 d. Urine first clear, on standing turbid with reddish – white sediment. Drawing in humerus, m., for a 2 day – 3rd d. Dislocative pain in muscles of left upper arm. – 4th d. Drawing in bones of right side of face and forehead, evening – No time stated. Drawing along thighs. Drawing in iliac region and thighs. (Ibid.)
7. Dr. HOPPE in the course of 1 hours dropped upon his naked left elbow 180 dr. of warm T., 5 to 10 dr. at a time every five minutes. the skin reddened gradually until it attained an intense red colour. There was itching extending beyond where the T was dropped, and burning which increased with very repetition of the application; the burning assumed a pricking character, the corium was somewhat swollen; there was slight numbness, and the affected part was very tender to the touch. (N. Z. f. h. Kl., vii, 178.).
Poisonings
1. A male infant, aet. 14 mo., swallowed Ziv (?) by mistake. It was found 2 hours afterwards in a comatose state; pulse 130; conjunctiva injected, pupils dilated, eyes watery; face flushed; breathing hurried; strangury, urine of violent odour; abdomen tender, especially along course of spermatic vessels. Emetics and cold to head were employed, and 10 hours after the accident he was much improved and quite lively; pulse 120; bowels loose, and 8 small worms had been passed. For 4-5 day he improved steadily, showing only a little excitement about brain, and after this was quite well. (EVANS, Journ. of Medorrhinum and Phys. Sc., Nov., 1846; from Taylor on Poisons.)
2. A young man drank about Ziss of the oil. Soon after he was seized with frightful praecordial oppression, and with all the symptoms of strong intoxication. All n. he lay drenched with sweat, in profound sopor, and woke next m. very weak and with bewildered head. He could not stand on his feet without staggering from side to side. After profuse emission of violet- smelling urine he was so relieved that by evening he only felt a little weakness. (SCHLEGEL, in Frank’s Mag., iii, 646.)
3. A young man took oil for taenia,- 3ss hourly from 8 a. m. till 3ij had been taken. After 1st dose burning in rectum, which lasted 2 day, much relieved by cold water enemata. He was purged 8 times during day, chiefly mucus and water passing, and towards evening had two copious emissions of urine, with burning. (OSANN, Ibid., ii, 886.)
4. A man took same for same. On 1st m. he had 3j in 2 doses within an hours, and in evening repeated dose; after latter he had burning in stomach, one turn of vomiting, and fulness of head. Next day ziss was taken in emulsion within an h. Soon after he experienced violent burning in stomach, colic, vertigo, and pressure and fulness in head threatening apoplexy. After 3 hours vomiting of oil relieved head, but breathing was laboured and colic continued. Five hours after taking drug a scarlet eruption broke out over body. In evening he had 2 stools, and next day some gastro-enteritis showed itself. (WIBMER, op. cit.)
5. A woman of intemperate habits swallowed an unknown quantity, possibly zvi. She was found dead, her body in rigid opisthotonos, eyes open, pupils dilated. Brain, lungs, stomach, and both sides of heart were gorged with dark blood, and 3vj of oil were obtained from stomach. (MAUND, Glasg. Medorrhinum Journ., April, 1857.)
6. An infant, 14 weeks old, swallowed 3ss. In about 1 hours it became insensible, cold, and slightly convulsed; 2 hours later pupils were contracted, pulse small and feeble, breathing very slow and irregular, with moist rales. Death took place at end of 15 hours (MIALL, Lancer, 1869, left 360.)
7. A boy 3 years old drank nearly 3vj of “camphine” (which is practically identical with T.). Within 1/1.2 hours he was in a state of profound coma, eyes suffused and injected, pupils dilated, pulse 130, skin dry and hot, mouth and fauces dry and parched, features somewhat contracted and anxious, and respiration hurried. The abdominal muscles were very tensely contracted, as he lay curved, with arms closely folded and pressed on the abdomen. The child could not be kept awake, even while vomiting. There was constant priapism, with frequent attempts at micturition, but only 4 oz. of urine, and that bloody, were passed during 18 hours, for which time the coma continued. For several day patient remained excessively nervous and irritable, but at the end of a week he appeared to be well. (HARRIS, N. Y. Journ. of Medorrhinum, N. S., x, 40.)
8. J. H -, aet. 27, porter, of temperate habits; never had dropsy of other symptom of renal disease. On March 21st, 1847, he took ol. terebinth., ol. ricini, of each Zss, for tapeworm. Soon after his head felt confused; he vomited once, and was purged 2 or 3 times. In about 8 hours he had frequent, almost incessant desire to pass water, passing only a few dr. at a time. The water scalded him very much, and contained coagulated blood. I saw him on the 22nd. He said he had passed water 14 or 15 times during the n., and as often in the course of the m.; the pain and irritation were now less than yesterday. the urine was deeply tinged with blood, and contained a large quantity of albumen. Under the microscope numerous blood – casts of the renal tubes were seen. A few small inflammation – cells and some crystals of the oxalate of lime were entangled in the casts; no epithelium; much of the blood was not molded in the tubes. On the 25th there was still a considerable quantity of blood in the urine. On the 27th the urine contained less blood and albumen; casts of the tubes were still visible, and contained, besides the blood- corpuscles, a large proportion of inflammatory cells, about twice the size of blood-corpuscles. On the 29th urine had the natural colour; no cloud with heat or nitric acid; it contained a very few blood and inflammation corpuscles, and a very few casts of tubes. On April 6th urine was pale, free from blood and albumen, but still containing oxalate of lime. (G. JONSON, Diseases of Kidney, p. 487.)
9. Oil of T. is often taken by labouring people for sciatica and other rheumatic pains, but sometimes with bad effects. A woman, aet, 60, whose dose I cannot determine, was seized with a pain in the kidneys and diabetes, The author probably means diuresis.–EDs. and died hydropsical in 25 d. Another took 3ij in warm ale, which soon brought on strangury, bloody urine, and its total suppression, with fever, violent thirst, and vomiting, so that I really despaired of being able to recover her. But she was happily cured by the warm bath and diluent drinks. (STEDMAN, Medorrhinum Essays and Obs., ii, 48.)
10. a Administered internally, in doses of 50 centigr. to 1 grm., T. excites a sensation of weight and heat in the stomach, soon followed by one of warmth in the skin, which may sometimes go on to perspiration. the urine next passed will have a peculiar odour, which has been compared to that of violets.
10 b. If the dose be as much as 4 grms., there is experienced a feeling of heat and acridity in oesophagus and stomach, a little anxieties, some nausea, but rarely vomiting, frequently colic with twisting feeling in bowels, considerable irritation and meteorism. Soon thereupon, in the majority of cases, there is general excitement, announced by febrile heat and a sense of warmth extending all over the body; hard and frequent pulse; headache, redness of face; thirst; dryness of mucous membranes; dysuria, urine being scanty and red or copious and pale, but in either case of pronounced violet odour; abundant perspiration, which, like the breath, smells of T.; weight at stomach, and in many persons a condition somewhat like intoxication. Finally, there is some diarrhoea.
10 c. If the quantity taken in 32 – 64 grms., either (1) the whole action is one of gastro-intestinal irritation,- to the local effects already mentioned vomiting, sharp colic, and frequent loose stools being add; or (2) absorption takes place, and to the signs of general excitement, yet more marked, are added those which tell of specific action on the urinary apparatus; on the mucous membrane, especially of the air tubes; or, more rarely, on the nervous system of the limbs. The first shows itself by considerable pain and heat in the lumbar region, especially over the kidneys, and in the hypogastrium; the latter region is sensitive to pressure, which causes- as in acute cystitis-vesical tenesmus, pains in urethra, and strangury; then ardor urinae, dysuria, sometimes actual urethritis; urine scanty, red even bloody; painful erections like chordee. More rarely the urine passes easily, and is copious and pale. The mucous membranes are dry as in the first stage of catarrh; they are injected, turgid, and hot; there is frequently herpes labialis, heavy substernal pain and tickling in the trachea as at the commencement of bronchitis, and the patients have been seen to bring up phlegm streaked with blood. The skin is sometimes reddened by erythematous patches of more or less brief duration; it may be vesicular or papular, as after the ingestion of shell- fish.”According to Berenguier, after comparatively large doses there appears a simple scarlatinoid erythema, spreading by preference over the face and the upper part of the body in irregular patches. Sometimes there appears upon the reddened surfaces, with itching, a large number of small papules, which give to the skin an eczematous appearance. In rare cases a vesicular eruption is noticed. A number of cases have been reported by Brochin(Gaz.des Hopitaux, 1879, p.99) in which erythema or an urticarioid eruption always showed itself in certain persons after the administration of T., either in solution, in capsules, or in a pure state.”(LEWIN. op.cit.) The effect upon the nervous system of the limbs consists of an exquisite sensibility felt most in the lower extremities; a general painfulness of the pats existing, especially along the course of the large nerves. Dr.ROTH relates two cases in which, after large doses of T.taken for tapeworm, neurotic phenomena in the limbs ensued. In one, a gentleman of 40, there were “neuralgic pains in various parts of the, especially in one or other of the lower extremities. He had no control over his hand and arm when attempting to write; when standing or walking his feet were placed far apart. During the two previous years he had been unable to ride on horseback. When dressing or undressing, though his feet were placed very far apart, his body swayed backwards and forwards.” The other, a young lady of 15, “soon after partially lost the use of her r.arm and l.leg. When I first saw her,” some 3 years later, “she had but little use in the r.arm. She could raise the shoulder-blade and bend the arm at the elbow; but the hand fell with a jerk in the position in which she wished to place it. She could only advance the arm from the body a short distance. She limped with the l.foot, and dragged the leg in walking; the ankle-joint was stiff.” (Monthly Hom. Rev., ii, 312. We share in Dr.Roth’s reserves as to the part played by the T.in such long-lasting disorders, and give the cases in a note only accordingly.–EDs.) Headache also, pretty severe, and lasting long after the subsidence of the other symptoms, is one of the most constant results of a too prolonged administration of T. (TROUSSEAU et PIDOUX, op. cit.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.