10. (No information as to dose, &c.) Great pain on the top of the whole left side of head, especially in eye; some pain in left foot. Pressive pain in left eye. Pricks in upper eyelid. Great quivering before eyes. Tongue as if scalded. Greasy taste. Violent pain in right hand, the whole arm is painful even when lying quiet and warm in bed; he has also pain in left foot, sometimes on the top, sometimes in heel, sometimes in toes. (FREITAG, N. Archiv, loc. cit.)
11. Dr. M. A. TINKER, health good, took, April 10th, 1866, at 3 p. m., 10 dr. of tinct. of dry root. 30 m., temples feel pressed together, with darting pains in eyeballs. 40 m., sense of constriction across chest, with inclination to breathe deeply, which much increases constriction, and causes tearing pain through breasts, especially right 45 m., drowsiness, coming on gradually, causing indisposition to move or make any mental exertion; sharp piercing pain midway between sternum and right nipple, surface feels tender on pressure. 1 hours, head feels dull and inclined to ache in temples, right most; sense of weariness and lassitude throughout system, yawning, disposition to lie down. 6 p. m., pain in right breast, very permanent and increasing, extending to stomach and causing sickening sensation. 9, dull heavy pain at root of nose, with dizzy sensation as from alcohol; also same feeling of lassitude, inducing her to retire early. 11th. – Pain in right breast has persisted all n., also troublesome dreams and restless tossing about, with painful sighing respiration and considerable dyspnoea. 7 a. m., severe aching in temporo-frontal region, and dull heavy pain about root of nose, with considerable coryza and stinging sensation in nose; mouth clammy and feverish; appetite and taste much impaired; weight as from indigestion in stomach; dry cough, with considerable tickling in throat-pit, and crawling sensation extending down beneath sternum; pains through hips and down right leg, very severe in Ist joint of right great toe, like gout. Latter pain lasted 2 1/2 hours; cough became very severe, causing considerable pain beneath upper sternum, with no expectoration, and lasting 2 h. At noon repeated dose. Intense burning pain between breasts, most severe on right side; feeling of weariness and lassitude all through system; dull pain at root of nose, with tingling sensation as in coryza; band-like constriction across forehead, just above eyebrows; pressing pains in both temples, with occasional darting pain through head; head feels dizzy, she cannot turn for fear of falling; sharp piercing pain in right breast, just beneath nipple, very difficult to take a deep inspiration, and some dyspnoea; spasmodic constriction directly beneath lower jaw and across throat, very distressing (lasting 2 or 3 h.); again sickening pain from right breast to stomach; shooting pains through bowels extending to lower extremities; very severe headache, now tearing, now boring, over and about right eye. extending to temple; right eyeball is very painful, especially on attempting to roll it outward and upward, sight dim, and considerable effort and rubbing of eye is required to see anything distinctly – a feeling somewhat like snow-blindness; inability to fix mind on any subject; some feeling as of indigestion; disposition to yawn and take deep inspirations, which cause intense tearing pain in right breast (there is also pain in left breast, but less severe), it extends downward to stomach and bowels, causing borborygmus, and upward to right shoulder, making it difficult to lift arm to head; wandering rheumatic pains through both lower extremities; right most severe; dryness in throat, with teasing dry hacking cough; moderate pain in back of head and neck, gradually extending downwards to region of kidneys, where it is very severe, dull, and heavy. 3 p. m., slight flushes of heat, followed by chills, and in less than an hour face flushed, with fever, hands hot, qualmish feeling with great lassitude and weakness all over; great increase of heat through right shoulder and clavicle to right breast, extending to stomach and bowels, pulse 86, resp. hurried; pain along inner border of right scapula, with heat and chills alternating, and extending down to kidneys, where there is great heat and pain,-pain from thence seems to penetrate into right iliac fossa, then to sigmoid flexure, then down into rectum, where it caused a very peculiar spasmodic pain of the most excruciating intensity for 15 m.; sharp pain in right ankle, also in great toe-joint; rheumatic pain in lower extremities; sneezing very frequently, with tingling in nares; throat very dry, with tickling cough; headache, very severe through whole forepart of head, extending down into cheek – bones (for 2 h.); both eyeballs very sore, with frequent sharp piercing pain darting through them, with dimness of sight. 9 p. m., recurrence more than once of pain through bowels to rectum; severe rheumatic pain in lower extremities, so severe in right ankle and great toe-joint as to cause serious lameness in walking, – some swelling in toe-joint. 12th. – Very restless all night; now (6:30 a. m.) severe headache; pain in chest through loins, and in extremities, with very feverish state of system, severe dyspnoea, sighing respiration-in fact, all the principal symptoms increased, including the weariness and lassitude, so that she is scarcely able to keep on her feet; mouth foul and breath fetid; eyes feel very weak, lids smart on closing them tightly, tears start if opened to light, eyeballs tender to touch; dull heavy pain across kidneys, urine deeper-coloured, and not quite as easily voided; pulse quick, feeble, and compressible. On taking a little exercise, frontal headache increases, with nausea; pain very severe in left temple, at times like clavus, with violent throbbing of temporal arteries. After a slight breakfast (eaten without appetite) dull heavy load in stomach as from something quite indigestible. Lassitude and restlessness increased, and she was hardly able to attend to anything; severe temporo-frontal headache, with soreness and beating; pain about root of nose, in cheek-bones, in breasts up to right shoulder, down back (especially severe in loins) and legs to feet. 2 p. m., light chills, followed by hot flushes, for 15 – 20 m. (pulse 95), when burning fever set in, with exacerbation of all symptoms; bursting headache; painful coryza; eyeballs paining much on moving them; tearing burning pain beneath sternum; very irritable and morose, impatient at least trifle; severe dyspnoea; head very tender to touch, as also other spots where pain had been severe. 10 p. m., fever subsiding and pains abating; pulse 65, easily compressed; very languid, she had taken to bed since fever set in; urine very high coloured, depositing a reddish sediment; return at times of the spasmodic distress in rectum; considerable burning in stomach. 13th. – A very restless n., till towards m. perspiration broke out freely, when pains abated. Now (7 a. m.) head aches; throat feels raw (also mouth), with some dysphagia; still severe pain in right arm (including scapula), in loins and down legs; head dizzy at times; vertigo and faintness on rising quickly from stooping posture or turning head suddenly. 10 a. m., faintness; no desire for food; less depressed. 12:30 p. m., mouth and throat still very sensitive, making it quite difficult to masticate; desire to take deep inspirations continues, with the tearing pain in right chest; pulse 75; moving scalp still painful, eyeballs very tender to touch; sharp darting pains from temple to temple. Return of fever about 2:30, less severe than yesterday, passing off between 8 and 9.
The drug symptoms now died away one after another during the next few day; the fever recurred for 4 or 5 day, subsiding in force, but always about 2-3 p. m.; pain beneath sternum and in right chest, dyspnoea, inclination for deep breathing, and dry hacking cough, were most persistent. (Trans. of Amer. Inst. of Hom., 1870, p. 408.).
Poisonings
I. Four persons took “a good drink” at a demi – john of tinct. of S., supposing it to be brandy. They were soon seized with severe racking and burning pains in stomach and bowels, with intense thirst; and all died the next day (Am. Journ. of Medorrhinum Sc., 1841, ii, 506.)
2. S. root sometimes powerfully excites the catamenial secretion, and occasionally it has been known to produce uterine haemorrhage. In large doses, it nauseates strongly; but independently of this effect usually occasions a quickly diffused and transient, but very peculiar nervous thrill, which pervades the whole system, and often extends to the furthest extremity. When pushed to an improper extent, it sometimes occasions vomiting, but more frequently burning at stomach, faintness, vertigo, impaired vision, insensibility, coldness, extreme reduction of force and frequency of pulse, with great irregularity of heart’s action and often palpitation, great prostration of muscular strength, and sometimes, though rarely, convulsive rigidity of limbs. In a few instances neuralgic pains have been produced in various parts of the system, and sometimes a violent but transient gastrodynia. In full emetic doses it speedily excites vomiting, but without producing much nausea or depression of strength; if pushed, however, in this capacity, it occasions, great anxiety, and the above – mentioned symptoms of narcosis. (TULLY, Bost. Medorrhinum and Surg. Journ., vi, 246.) NOTE. – For Dr. Pilling’s proving, see Appendix.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.