5. a. HROMADA. – Immediate effects of drug were local, – burning in tongue, throat and gullet, salivation, nausea, retching, borborygmus; flatulent emission, urging to stool, then some diarrhoea; with this there was vertigo, and weight and pressure in head. After 3 hours head was as after being fuddled, without vertigo or pain, but he felt cheerful; n. was very restless, with pressive pain in right thigh and right upper arm (same continued for 5 following n.). On 2nd day, and lasting 6 day, burning in anus before stool, as if a fiery coal were there; urine somewhat copious, and slightly tinged with blood; itching as from lice on vertex, obliging him to scratch incessantly (lasting 2 d.). On 3rd day vertigo while getting into bed, so that he had to support himself; at n. excessive itching all over body, compelling scratching, which causes a burning (for 1 hours). On 5th day furious itching in fingers and toes, waking him from sleep and obliging him to scratch, which causes burning (for 1 hours); violent pains in both thighs, as if compressed, abating somewhat while legs are stretched, increasing at first but diminished afterwards by movement (lasting 4 d.). Without note of time, – dullness of head without vertigo or real aching; after – taste of ingesta; burning in abdomen and rectum for an hours after every stool; itching of anus, with violent burning after scratching, for 5 days; great oppression of chest, making him feel as if he would collapse, with great anguish at heart (for 1/2 hours); a sort of scabies between right fingers, itching much, but only at n. in bed, nothing visible by day; much drawing pain in whole right lower extremity (lasting 8 d.).
5b. The following symptoms, accredited to Hromada, belong to a female prover, who also may have supplied some of the above: – violent itching of scalp, followed by burning, compelling scratching till blood came (in 5 hours, lasting 5 d.); frightful burning in stomach immediately on waking, mounting up to throat, making her feel as if suffocating; for 3 n. in succession furious itching on hands and feet, as if she had scabies (from 2nd n.); for 5 hours on 3rd day very lively mood, which was not natural to her. (Ibid.)
6. LANGHAMMER. – [Dose seems to have been taken early in d.] In 1/2 hours, burning itching creeping and prickling on upper and under lips, as if parts were burnt, obliging him to scratch; febrile shudder through whole body. In 3/4 hours, trembling of right hand while writing, as from weakness; some borborygmus. In 1 hours hiccup, several times; some stitches in muscles of left forearm from within outward, going off on least movement. In 2 hours same in upper arm, with sense of pressure near wrist, and much trembling of hand when holding or lifting anything. In 2 1/2 hours some external stitches in left knees, while sitting. In 3 – 4 hours same on left temple; beating and twitching in muscles of left upper jaw; during inspiration stitches externally on left chest, and same on right black in rapid succession; painful pressure in left sole while standing. In 5 hours, feeling of burning heat, heat and redness of face and heat only in forehead, without thirst. In 6 – 7 hours, tearing stitches externally on left forehead; pricking boring pain within outwards in right chest during expiration, while sitting, which soon goes off on slight movement. In 9 – 10 hours painful pressure from above downwards on left temple near ear; again stitches in left forearm. In 10 – 12 hours stupefying oppressive sensation in forehead, causing sense of reeling which makes him stagger from side to side as if drunk; painful pressure on left temple; while writing, creeping pricks from right thumb to index finger; pressive pain on left index, going off on movement; intermitting stitches in muscles of right thigh, while sitting. In 13 – 15 hours some stitches in left abdomen, while sitting; pressive pain under elbows when bending arms; when moving arm pressive pain in upper muscles; crampy, painless drawing together of left little and ring fingers, while at rest; pressive pain in left hip, while sitting; sudden burning heat of cheeks, with coldness of forehead, without thirst. The whole day he was absorbed in revive; n. was disturbed with complicated but unremembered dreams; in m. he woke suddenly as from right. (Ibid.)
7. RUCKERT. – Vertigo as if everything were turning, especially on rising after being seated (1 hours); vertigo as if he would faint, with obstruction of vision (3rd d.); pressive headache on vertex, rising up from skin of forehead, where a sort of whirling movement is experienced (2nd d.); headache, especially after every walk; on entering room she is attacked with a turning screwing pain, commencing in right head, affecting both temples very acutely, and extending over whole head after going to bed (recurring every d.); tension of scalp, especially during fever; shootings in temple and scalp (2nd d.); blue rings round eyes for several day; otalgia with crackling before ears; humming and buzzing in ears, and sometimes sound as if something heavy had fallen on the floor and burst, after which the ears ring for a long time; dullness of hearing, feeling as if something were in ears. Drawing in jaws and cheeks; frequent painful jerking in gums, recurring daily; swelling of uvula; burning and aching in throat, between as well as during deglutition; throat feels internally swollen; throat feels as if tied round with a string (3rd and 4th d.); nausea while eating, several times. Hoarseness; short difficult breathing, especially p. m.; wheezing in larynx on inspiration if she lies down; oppression of chest while sitting and lying, as if a large heavy stone lay on it; palpitation, and therewith sense of throbbing in all vessels of body. Pain in spine as if bruised, while sitting; cramp – like jerking in elbows; yellow spots on fingers; during whole action of drug great dryness of hands; trembling of arms and hands; burning of knees; prickling in toes, as if “gone to sleep; ” cold feet; pain in limbs, especially lower, a peculiar painful drawing in middle of bones, compelling their stretching out, better at rest, each movement evoking feeling of weight and stiffness; in movement and walking his joints crack; bruised pain at various spots, now here, now there, acutely felt but transient. Considerable pricking under skin all over, lasting some day, especially in toes; great weariness and heaviness in all limbs, especially legs; relaxation of whole body; violent tremor of body, especially 3rd d. Constant desire to sleep, even in daytime. Chill with goose skin and moderate thirst; flying heat all day, most a. m., alternated with chilliness; febrile condition, he feels ill anxious, restless, starts readily, breath short and hot, tremor, strong ebullition of blood, eyes languid and unsteady; it is as if everything – even the air – quivered before her, there is irresistible desire for sleep, with yawning, icy – cold shudders without shaking, constant nausea; heat only at n. and on rising in m., mostly inward – hands, forehead, lips and cheeks only being hot to touch, hands always dry and rough, mouth in m. very dry and sticky, thirst moderate but appetite for savory food, no sweat (this for two weeks, daily the same). Fearfulness, starting at least noise. (Ibid.)
8. SCHONKE. – Flush of heat over face, cheeks are red and burn; shooting in right auricle (2 hours). Shooting pain in an anterior left lower molar, extending towards ear, lasting some m. (4 hours); scraping in throat with confluence of saliva (later, sweetish) in mouth (immediately); he feels as if a soft body had stuck in his throat, felt most on swallowing; scraping in throat, when swallowing he feels as if uvula were resting on tongue, and this troublesome feeling causes him to hawk, which brings up a sweet flat – tasting mucus; burning and pressure in throat which feels during empty deglutition as if a plug were fixed there (20 hours); dryness and roughness in throat on swallowing (2 hours); tensive clawing sensation in parotid, with increased flow of saliva on that side (1 hours); sweetish taste in mouth, as if he had chewed liquorice (1 hours); empty tasteless eructations with shuddering feeling over body, after which a preceding qualmishness goes off; nausea and inclination to vomit, he spits up water all the time (1 hours); feeling of warmth in right hypochondrium (soon) and (1 hours) in praecordia; full shooting pain to left scrob. cordis; shooting in right side, especially in hepatic region (6th d.). Oppression on chest (7 hours); violent cough (immediately); nightly dry cough, which allows him no rest, – he is hot with it and sweats; short dry cough, brought on by scraping sensation in throat; shooting in mid – chest, right, in front, during inspiration and coughing, it wakes him several times in n., he cannot lie on that side, – therewith cough with expectoration, frequently recurring during night; shooting in left side, at first more in upper than in lower part, worse when coughing and inspiring deeply. Violent pain about sacro – iliac symphysis while bending; pain in sacrum, with shivering; pain near ant. sup. spinous process of ilium, relieved by walking about and pressing upon it, worse when sitting (1 hours). Sudden cramp in right hand, he is unable to grasp anything with (2 hours). Shuddering runs over back, he feels chilly through whole body (3 hours); frequently recurring shuddering and shaking, soon passing off, without immediately following heat and without thirst, he then feels hot all of a sudden, especially in face – as if not breath were coming out of mouth and nose and warming all the neighbouring parts, no thirst, body generally feeling comfortable and head bright (the shudderings recurred 8 – 10 times within a short space, the attacks of heat came seldom, but lasted longer); during burning heat in face a chill runs over whole body, especially extremities (2 hours); violent chill at 5 p. m., coldness runs through back as if cold water had been poured there, and teeth chatter with the internal chilliness, – the stove brings some relief, and after 2 hours the chill goes gradually off, and body becomes warm with some sweat on forehead (during following n. shooting in chest with cough). (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.