1b. An observation of Rannelt’s may be mentioned in this place. After the subcutaneous injection of 0.02 grm. in a patient with uraemia there appeared next m., after diaphoresis had passed off, a swelling of the submaxillary glands, to the seize of a fist, and also of the parotids and tonsils, with fever. Under the use of atropia these phenomena passed off in the course of a d.
1c. Great danger is incurred by the untimely use of P. in eclampsia. Sanger reports 3 such cases, in which the injection of 0.02 grm. was followed by edema of the lungs. In one case, life was saved by the antidotal employment of atropia, but death occurred in both the others. Sanger explains this injurious action of the drug by the deficient expectoration of the masses of mucus which are formed under its influence, and their entrance into the lungs. Expectoration cannot be performed, because unconsciousness and loss of activity are produced by the eclamptic attacks. (LEWIN, op. cit.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.