9b. Immediately, nausea as though she would vomit, with burning in mouth. Hunger, which was previously present, goes off for several h. After 10 mm., on back of tongue sour taste. After 1/4 hours, painful pressure over right frontal protuberance. Over right eyebrow an obtuse pressure as with a peg, which extends to occiput. Vomiting of sweetish water, m., before food. Twitching tearing in right knee, when at rest. Weakness as though she had not slept enough with warm feeling in eyes. After 1/2 hours, on the street she had vertigo, causing staggering, she was as if tipsy, and had to return home; the vertigo went off in the room. Retching such as she used to have in the first month of pregnancy, m. Sneezes 5 or 6 times in succession. Feeling as if mucus stuck in throat, making her constantly hawk, after a while she expectorates sweet – tasting white mucus. In the centre of chest feeling of weight, with dyspnoea, so that she must often involuntarily take a deep breath. Breathing difficult, as though chest were compressed, causing her to breathe deeply. From centre of chest up to throat a burning as though brandy had been drunk, even the tongue is painful, as though it had been scalded, with heat, redness and tension of face. In the middle of right side of chest, I inch on sternal side of nipple, a very painful and obtuse shooting pressure, which goes through the chest and is felt at apex of scapula. Whilst writing a feeling of cramp in point of right elbow, nearly preventing him writing. After 1 hours, stupid and empty in head; her thoughts leave her for instants, so that she knows nothing; this occurs repeatedly during d. In right iliac region a frequently recurring pain, which radiates upwards and downwards and extends into right testicle. She has a feeling of coryza as though the nasal m. m. would swell. A pricking pain on back of left hand betwixt thumb and forefinger. After some hours, abdomen very much distended but soft, with dyspnoea all d. After 2 hours, pains in chest as if sternum were pressed in. She is chilly, her hands are icy cold. Chill all over body, the skin is as if dead, and she feels all through body as if she had been up all n. and had not slept. Rigor, with flushes of heat in face, drawing and shooting pains in both temporal bones anteriorly, pressure in eyeballs and a veil before eyes, hindering vision and making her rub her eyes, whereupon scalding and acrid tears flow, and the white of the eye looks inflamed. After 3 hours, in right temple anteriorly tearing and shooting, involving upper and lower molars. Painful feeling in sinciput as if several hairs were seized and pulled out, felt even next d. After 4 hours, in sinciput beating as if with a hammer, and in temples shootings, which occasionally cease, but always recur; on stooping, feeling as if all would be forced out at forehead (for 2 d.). On right side of abdomen, between navel and crista ilii, some violent stitches, which take away her breath so that she must cry out, when at work. Urine turbid. In right palm, betwixt thumb and forefinger, and agreeable itching, lasting 1 hours, not quite removed by rubbing. Chill all over body, so that she shivers, with great heat of face, bright red cheeks, icy cold feet, feeling of weight from shoulders to elbows, so that she could not raise arms to head, only felt when moving, with great crossness, lasting from 10 a. m. till 10 p. m.; slept well, and was all right next m. A rigor of 5 hours duration, then heat of face and hands and cold feet, mingled with chilliness, from 2 to 11 p. m. After 5 hours, all objects appear dim, like a veil before eyes, lasting several h. Hot, red ears, which burn, as when one comes from the cold into a warm room, with cold feet. At 3 p. m. pain in scrobiculus cordis, as if a thread were drawn through or a small muscular fibre were torn out, which goes through all limbs, when at rest. After 6 hours, stupid in head, she looks straight before her, she does not know why, and hears and see nothing and is quite without thought. Digging in sacrum as though something would come out. After 7 hours, towards evening, crawling in upper bronchial tubes, causing cough. After 8 hours, when she wants to do something and has walked about a dozen steps, she stops and knows not what she wanted to do. A spasmodic throbbing pain on inner and lower part of left elbow – joint, which occurs in single fits, p. m. From right tuber ischii down to middle of thigh on its outer side, drawing pain as if in bone, with chilliness. In the middle of left thigh a penetrating twitching pain, when at rest. After 9 hours, spasmodic drawing from lumbar vertebrae to genitals. After 12 hours, drawing tearing, beginning in middle of squamous suture, going through temple and left side of face, involving upper and lower teeth of that side, lasting several h. Bitter taste in throat, evening, takes away relish for food. On moving, the whole abdomen in painful as if ulcerated, going off by rest; these pains last 20 hours, and hinder her from sleeping well at n., so that she must turn about frequently, she then sleeps for a little while and soon wakes again. Must rise every hours at n. to urinate, and each time much clear urine passes. Violent urging to urinate, she cannot get out of bed quickly enough to do it, with contractive pain in vagina. Violent itching in vagina, she must rub herself, afterwards soreness, the external genitals swells, become hot and hard, and on urinating the vagina feels sore, e. Sleep at n. disturbed by pressure and burning in eyes, lies awake till m., then goes to sleep for a little while and wakes with eyes sealed up. After 16 hours, she sleeps all n. without consciousness, not usual with her, is quite well in m. After 18 hours, from the gastric region all through the upper part of the body a working and beating in all blood – vessels, worse on moving. After 20 hours, on waking m., a foetid smell before nose. On rising m., rigor with bright red epistaxis. After 21 hours, as if downy feathers hung over eyes, making her wipe them constantly. After 22 hours, 2 days after menses, a contractive pain in vagina, making her start, whereupon a white discharge took place from vagina. After 24 hours, drawing pain in head, so that the eyes are closed. Pressive pain in sinciput as if all would come out there. On right side of head pressive pain, which seems to come from cervical muscles. On looking for a little while at an object, the eyes become moist, which interferes with vision. A jerking shooting in right antitragus, which is somewhat swollen and stiff, and has shooting pain when touched. Tongue clean but pale and as if withered, with thin saliva in mouth, no appetite, but much thirst; throat always dry, so that she must drink much. Bitter taste, m. She has appetite but no relish for food, at same time feeling of fulness, as though she had already eaten largely. Tightness and distension of belly, without pain. Pain in abdomen, deep down in abdomen the pain is like an ulcer, mixed with electric shocks in the internal sexual organs, which cause pinching, spasmodic pains in external labia, making her start every time the pain occurs, with a periodical pressing proceeding from sacrum forwards, with frequent call to pass urine, but only little clear urine comes; ineffectual urging to stool and anxious uneasiness through whole body, so that the sweat of anxiety breaks out on her, with ill humour, so that she feel inclined to quarrel with and beat someone; when these attacks take place while she is seated she must rise up and walk about, when the pains go off; this state lasts 4 d. Above and round navel a slight pain, which she cannot describe accurately, or such as follows drinking water after sour food, with ill humour, lasting 36 h. Drawing tearing, and shooting in rectum, with frequent ineffectual urging to stool; after 36 hours, with much pressing a hard stool is evacuated, when all the pains cease. When she presses at stool there occur spasmodic pains from lumbar vertebrae to right inguinal region, they extend to right hip – joint, and are a great hindrance to walking. She must often breathe deeply on account of heavy feeling in chest. The whole external chest pains as if pressed in. Drawing sacral pains down along coccyx to rectum and vagina, where they cause spasmodic contractive pains mixed with shootings, pains, diminished by rising up, but return in fits (like labour pains), after such attack leucorrhoea like whey gushes from her. A paralytic pain darts like lightning to left hand, so that in a moment she lets fall what she was holding. In middle of left femoral muscles a pain as though she had received there a hard blow, worst when seated. She is very cross, and must frequently weep without cause. After 29 hours, in lower parts of ear pain composed of several stitches proceeding from top of right shoulder. After 30 hours, at back of shoulder – joint, stitches which dart through whole arm down to fingers; in the latter they cause a sensation as if gone to sleep, with insensibility and powerlessness, so that she cannot hold anything firmly in the hand, if she has no stitches she has jerking in hands, with creeping and heat of them. After 32 hours, the scapulae are painful, as if they had been beaten. After 36 hours, pressive pain in head, all seemed to be forcing out at forehead, with pressure in eyes, extending up to crown. A digging and griping pain round navel, which goes up into throat and causes her to feel sick and inclined to vomit. On right side under false ribs in hepatic region a constant shooting pain for 6 h. Frequent sneezing, nose not stopped up, and yet feels as if she could not breathe freely through it. Nocturnal back pains, so that she can hardly lie, they extend over left hip, settle in flank, and involve left inguinal region, so that she can hardly raise herself up, the back pains worse when at rest than when moving. Several successive stitches in right ankle – joint, which radiate out to toes and involve the whole foot. When walking, heaviness of feet. At 9 p. m., chill, first in feet, then in back, head, and arm when she is chilly up to fingers, with feeling as if those parts were cold, which is not the case, lasts I m. After 42 hours, spasmodic pains in rectum, which extend upwards to iliac region, so that she must walk bent double and must sit down carefully. After 48 hours, obscure pains in whole abdomen, not increased by touch. Under left mamma several successive stabs, as with an awl, which radiate upwards and over right mamma, and severe shootings under right scapula, hindering breathing and lasting 5 m. After this pain under left mamma has lasted 1/2 hours, it darts thence like a sharp knife – thrust across scrobiculus cordis towards right side of chest, right side of abdomen through thigh and leg, and ends in ankle, all like an electric shock, p. m. On lower part of upper arm on its inside pain as if she had had a blow, only felt on being touched. A quarter of an hours after rising in m., the first 2 phalanges of all fingers go to sleep, there is formication in them like ants, and they are quite white like dead hands, no feeling in right index. Weakness in knee – joints, as though they would knuckle under him, when moving, for I h. In right ankle shooting, worse on moving. From 9 p. m. till 2 a. m. she lies awake in bed with sacral pains, internal chilliness, and strong pulsation in head, and tosses about. She is sad, and wishes constantly to weep. After 52 hours, burning in soles from 2 p. m. till 3 a. m., these pains recur for 4 successive day at same time. After 56 hours, drawing shooting on right side near sternum, betwixt 2nd and 3rd ribs. After 60 hours, drawing pain in the upper posterior right side of ribs spreads forward and causes shooting in mamma of same side. Tearing in legs from ankles up to knees, causing tension in calf. After 72 hours, on rising, m., mucus mixed with blood is discharged from vagina. A scrappy, rough feeling under sternum compels her to cough, and after several coughs she expectorated some dry, tasteless mucus, whereupon the cough ceased. After some day, when combing hair the scalp is very painful, especially when she combs over temples, with falling out of hair. Violent, constant, and very painful stitches in right side of chest, lasting several day, and much aggravated by in and expiration. On walking, m., she felt sacral pains, worse after rising, extending forwards to abdomen, and these cause a pressing like labour pains, they go down into legs, cause anxiety and trembling through whole body, with internal rigor (like irregular labour pains), intermingled with shootings in external genitals, better when lying, worse when sitting and walking. During first days she never felt as if she had slept enough in m., all her limbs feel paralysed. After 2 days, she has always much heat and watering of eyes., She wakes in m. with desire for coitus. Periodical drawing in mammae, going from outer side to nipple. Just above knees and for 3 inches up tensive pain in muscles, the parts are painful when pressed on by the hand, as though the flesh were torn, not felt when at rest, right worst. After 3 days, drawing pains in head from right frontal sinus to middle of right jaw, lasting several hours, beginning in m., ceasing at noon, again becoming bad at 2 p. m., and lasting till e. On right side of sinciput violent stabs as with an awl, so that she does not know what she is doing, her thinking power is completely gone, she goes with this pain to bed, soon falls asleep, and dreams all n. of indifferent things; in m. all pain is gone; it commences in afternoon. After the pains in arms and legs have lasted 60 hours they cease all at once, but immediately afterwards she has great distension of abdomen, as though she was pregnant, with exhaustion, nevertheless she is cheerful; she went to bed at n. with the distension, and in the m. was quite well. A zigzag shooting round navel, lightning – like stitches dart sometimes upwards, sometimes downwards, sometimes across, then a rapid shoot goes to left mamma, where it ends, lasting 1/2 h. In left iliac region, opposite crista ilii, persistent shooting, which darts down into left thigh. At n. pressure and forcing on neck of bladder, such as she usually has has before confinement, causing a feeling all through her as though she should be confined; this makes her rise 3 times to urinate; each time much hot, light – coloured urine is passed. After the leucorrhoea has lasted 24 hours it ceases, and she feels exhausted. At 4 p. m. she had stitches in right shoulder, 1/2 hour later she had several stitches in left side of chest, and at 6 p. m. she had a very severe drawing pain in right foot. For 3 n. never gets to sleep before I or 2 a. m., then she sleeps with many dreams, and on waking at 7 a. m. both arms were asleep up to elbows. After 4 day, urine hot and has a disgusting smell, like boiled juniper wood. Just above the heart violent stitches in chest, which prevent her breathing freely, the pains are relieved by pressure with the hand, last I hours afternoon. Drawing shooting under left short ribs when moving and when at rest, e. Labour – like sacral pains cause fruitless urging to stool, with distension of abdomen. Burning drawing and shooting, beginning round ankles and going through soles and toes, the pains are worst in soles, form a. m. till p. m. Soles of feet as if gathering. After 5 day, drawing shooting in lower parts of left ear, spreading all over auricle. From 4 a. m. till noon must urinate every 1/2 hour, and half a pint is passed each time. After sacral pains and heat of face has white discharge from genitals as profuse as menses. Contractive pain like cramp in right calf down to ankles. After 6 day, drowsy, much yawning, with putrid taste and little appetite. Bad sleep, tosses about in bed all n., changes from side to side, and can assign no reason for her sleeplessness, and on rising m. her whole body was weary, on the slightest corporeal exertion warm sweat breaks out all over body, she must frequently sit down to rest herself, when she stands up she collapses, lasting 12 h. After 7 day, the skin of crown and sinciput is painful when combed and when touched with fingers, as if ulcerated; when the skin is not touched the pain is drawing, worst on crown, lasting 24 h. After 10 day, the 3rd day of menses, at 5 a. m. a puffing and crackling in abdomen, like dull shots, then very urgent call to stool, with painless diarrhoea; during day 7 more diarrhoeic stools, without pain. (Archiv, xvi, 2, 187.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.