12b. To a boy, aet. 8,8 gr. of the chlorate were prescribed thrice daily for pustular ophthalmia. After 4 day the eyes were much better, but the mouth became affected by most acute ulcerative and follicular stomatitis. The whole mucous surface was red, and on the tongue, lips, and cheeks, & c., were numerous grey – based ulcers. The salt was not suspended, and in about a week the mouth was well again.
12c. A little girl suffering from pustular ophthalmia. Stomatitis resembling that of the previous case, though less severe, was induced by the chlorate. It also disappeared whilst the remedy was continued.
12d. A similar case occurred at the Metropolitan Free Hospital, also in a child. (HUTCHINSON, Lancet, 1858, vol. i, p. 265.)
12e. Two years ago I gave the chlorate to a lady pregnant for the fifth time, and whose previous labour have all been premature. After using it for about 10 day she became affected with spongy swelling of the gums, accompanied by small, highly irritable ulcers on the tongue, cheeks, and gums, and the considerable salivation. These symptoms disappeared on giving up the medicine, but their appearance was always attributed by my patient to the use of the chlorate. The lady having again become pregnant I recommended her to resume the chlorate, but she had only used it for 8 day when the same form of stomatitis recurred in a severe degree, and at once yielded on discontinuing the mixture. She has never at any other time suffered from sore month in any form. (JNO. TRAILL, Lancet, 1858, vol i, p. 375.).
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.