2 o. Skin. – Small, red, slightly thing pimples on upper part of forehead, and on scalp above ears, and at occiput; small furfuraceous tetter at concha of left ear, with burning pain only when touched; itching of cheeks here and there, on eyebrows, and on chin; small, white, miliary vesicles on a red ground, at left wing and tip of nose; yellowish spots of size of sixpence, of irregular shapes, and slightly itching, on right cheek, morning and evening; red humid tetter (after 8 days) on upper lip, which is swollen and painful when touched; heat at skin of scrotum, redness and slight dampness between scrotum and thigh; superficial excoriation at glans and prepuce; boil on pubes; red spots, slightly itching, on sternum and right axilla; red itching spot on left arm.
2 p. Sleep. – Drowsiness in daytime; restless sleep at night; coldness of feet, knees, and thighs at night; frightful or lascivious dreams; frequent waking; wakes early, and is unable to fall asleep again; sour-smelling sweat at night; profuse inodorous sweat in morning.
2 q. Miscellaneous. – Excessive sensitiveness to damp and cold; paroxysms of spasms and other hysteric symptoms. ( Mat. Medorrhinum, sub voce.)
3. June 18th, 4 p. m., 10 dr. of C.; 7 p. m., 20 dr.; 9:30 p. m., 20 dr. -19th, 7 a. m., 20 dr.; 7 p. m., 30dr. 8:30 p. m., urine increased in quantity, smelt strongly of C., frothy, dark yellow, strongly acid. -20th, 8:30 a. m., 30 dr.; 7 p. m., 40 dr. urine as yesterday. 9 p. m., severe aching in right elbow. joint, last night it was in right shoulder. – 21st, 9 a. m., 40 dr.; 4 p. m., 40 dr. Urine as yesterday. When walking, severe pain in right ankle-joint. -22nd, 8 a. m., 40 dr.; 1 and 3 p. m., diarrhoea; 10 p. m., 40 dr. In bed, severe pain in left wrist. – 23rd, 8 a. m., 40 dr., – 24th, 8 a. m., 40 dr. When walking, aching in knee. 2 and 10 p. m., 40 dr. At night, frequent micturition, much clear urine. – 25th, 8 a. m., 40dr. At 9 a. m. and 3 p. m., liquid stool; 8 p. m., without pain. – 26th and 27th. No pains, constipation. – 2th, 9 p. m., 50 dr. – 29th, 8 a. m., 50 dr. Severe pain anteriorly in right ankle-joint when walking and when at rest. 10 p. m., 50 dr. Frequent urging to urinate, even immediately after passing urine, lasting several hours, at same time persistent tickling in glans; the same at 11 p. m. in bed. Constipation. – 30th, 8 a. m., between 60 and 70 dr. Two stools, drawing in urethra. – July 1st, 7:30 a. m., 70 dr.; 9 a. m., liquid stool, also at noon. 4 p. m., 70 dr.; 10 p.
m., liquid stool. – 2nd, 7 a. m., no pain; no urging to urinate. Increased discharge o mucus from rectum. Several small stools and all day urging to stool. 10 p. m., 70 dr. At night vomited 4 times. – 3rd, 8 a. m., copious loose stool, also in evening. – 4th. Loose stools morning and evening. – 5th. At noon and several times during day, loose stools. The following day, normal stools morning and evening. After every dose, frequent eructation with odour of C. In all 2 oz. of C. were taken. (LEMBKE, N. Z.F. h. Kl., xi, 161.)
4. WEICKARD took 3iss of the “Mistura copaibae, ” containing about 20 gr., 3 hours after a full meal. The urine passed after 45 morning gave no precipitate or turbidity with
nitric acid, but some passed after 1 hour 20 morning became opalescent on addition of either nitric or acetic acid. The same reaction occurred with that passed 2 hours. After, but not with the next installment, passed 9 hours after taking drug. He subsequently took 3iij of mixture 2 hours after a full meal. Urine passed after 20, 40, and 60 morning gave no reaction, but a turbidity was produced in that passed 1 hour 25 morning after taking dose, and the precipitate was abundant in that discharged 50 morning later. Twelve hours after taking medicine, urine became only faintly opalescent on addition of acid, and it was not further noted. (Guy’s Hosp. Reports, 1876, p.1.)
5. a. BERNATZIK took 18 grm. of the oil in 3 doses during 12 hours. It caused acceleration of only few beats per morning impulse and rise of a fraction of a degree in the temp., with- after a time-violent gastric and intestinal disturbance, characterized by vomiting and purging. Complete strangury was not produced, but there was some difficulty in passing the urine, which caused decided burning in the urethra.
5 b. In his experiments with the balsam, b-exhibited 15 grms. inside of 5 hours. It acted as an emeto-cathartic, causing a great deal of pain and irritation. (H. C.WOOD, op. cit.)
6. KONIG, medical student, took at 8 p. m. 2 tablespoonfuls of an emulsion of 1/2 oz. cop. in 4 oz vehicle. After each dose increased secretion of saliva and frequent eructation. Next day, 8 a. m., 2 tablespoonfuls. Between 11 and 12 a. m., rumbling and flatulence in bowels, with feeling as if bellyache were coming on, soon going off. 4 p. m., 2 tablespoonfuls. After 1 hour, griping, inclination to vomit, 2 liquid faecal stools in 2 hours. Faeces and urine salt of cop., the urine was more copious and more frequently passed, with slight itching and smarting in urethra before and after micturition, but not lasting long. On 3rd day, 7 a. m., 2 tablespoonfuls. After 1/2 hour, great inclination to vomit and colic; this went off after perspiration. No appetite all day. 2 p. m., 2 liquid stools in rapid succession. 7 p. m., a firmer stool. (WIBMER, ii, 184).
Poisonings
A patient affected with gonorrhoea, after the inflammatory stage had passed, took 3ss of cop. Next morning the discharge had stopped, but all over body and even on face large wheals appeared like urticaria. At same time constipation and some fever. The eruption went off after a purgative, on which the discharge reappeared. The patient again took cop., and had a return of the urticaria. (ROMHILD, Medorrhinum Ztg. v. Verbascum f. heilk. in Preussen, 5th jahrg., No.36, p. 181).
2. A recruit, aet. 20, had gonorrhoea, and by advice of his comrades took in 5 or 6 days about 3iss of cop. the discharge was much diminished, but after 2 days of malaise there came on with strong rigor, followed by great heat, an eruption consisting of lentil-sized, red, elevated spots, dark in their centres, where they were most elevated. the eruption resembled measles, and was combined with itching and pricking in skin. The fever declined on the 3rd day. The eruption became paler, sharply defined, and remained elevated. After 7 days the cutaneous surface appeared marbled, spotted, pale bluish -red, and the sharp definition of the several spots was effaced After 14 days, the eruption had quite disappeared. It left the face before the chest and arms, and lingered longest on the legs. No desquamation. (GROSHEIM, Ibid., 6th Jahrg., No. 8, p.36.)
3. A man aet 20, had been taking 150 dr. daily for gonorrhoea. ON the 4th day the discharge diminished considerably, but an eruption came on similar to the above, only that the spots were larger and more elevated in the centre. The 3rd day, the eruption disappeared from the face, the 4th day from the chest, but it remained on the arms till the 6th day, and on the backs of the hands till the 14th. NO desquamation (Ibid., p.37)
4. Lieut. v. X-had been taking 150 dr. of cop. daily for gonorrhoea. On the 5th day the discharge ceased, and 2 days later, when he had ceased to take the drug, an eruption like nettlerash appeared. It came first on the forehead, then on the backs of the hands, and after wards on other parts of the body. In 8 hours the eruption was general; it was attended by burning in skin, slight soreness of throat, and a feeling as if sweat were going to burst out, which it did after patient got into bed. The eruption consisted of discrete elevated red spots and wheals like those caused by bug -bites; it was confluent only on ears and backs of hands. The 6th days the redness was quite gone, and where the eruption had been the skin was of a brownish yellow, like the so-called liver spots. No desquamation, except on ears, where there was a bran-like desquamation. After 4 weeks the brown spots on the skin could be seen when the patient was in the cold. When the eruption disappeared the gonorrhoea returned. (LOWENHARDT, Ibid., 8th Jahrg., No.32, p. 159).
5. A man affected with gonorrhoea was treated with cop 3j night and morning. On the 3rd day the discharge was gone. On the 4th day there broke out an eruption reassembling variola discrete in its 3rd day. The spots were dark red, slightly elevated; they reached their height in 12 hours, and then declined and became petechial spots, which spread around and became confluent. There was slight pain and moderate headache. The eruption was gone on the 5th day. (LISLE, Rec. de Mem. de Medorrhinum, v. xxiii, p. 108.)
6. A phthisical patient, aet. 40, had taken, on account of profuse expectoration, from January 26th to February 4th, about 3iss cop. with 3iss tinct. opii, when an eruption came all over body, resembling roseola, only the spots were larger and more elevated, some confluent from the first on some parts of chest. on leaving off the medicine the eruption went off in 4 days, and there was very little desquamation. (LANGE Deutsche Klinik,1853, no.36, p. 397.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.