Introduction
Convallaria majalis, L. Lily of the valley. Nat. Ord., Liliaceae. ‘.
Provings
1. IRVIN T. LANE. I made a note of my symptoms for only 2 days before taking convallaria, and as I thought this was not as long a period as I should have taken i did not record any symptoms that I could remember ever having before, so I think there will be no symptoms noted that were not caused by the medicine. I was in good health before taking convallaria, wit the exception of a slight coryza. Age 21; health good; eyes blue; hair brown; head large; from stout; features full; habits good; bowels regular; urine normal; chest large and full. December 24th, 1882, I began proving tinct, prepared by adding 7 parts of water and alcohol to 1 of fluid extract of flow’s, 3 times a day between meals. at 11 a. m., took 2 dr. 2 p. m., felt sleepy after coming into warm room. 3, took 3 dr.; feel very sleepy in warm room. 8, took 5 dr. Urine, sp. gr. 1032, contained some earthy phosphates, and, according to more’s est, between 1 and 2 per cent. of sugar. 25th, 8 a. m., urine 1025, contained about 1 per cent of sugar. 12, morning, took 5 dr.; 5 p. m., took 5 dr.; 9, took 5 r. Urine, sp. gr. 1028, contained some phosphates. 26th, 11 a. m., took 5 dr.; 4 p. m., took 5 dr.; 4 p. m., took 5 dr. 8, took 5 dr. Sp. gr. of urine 1026, it contained quite an amount of phosphates. 30th. -awoke about 2 a. m., and was very restless for some time; then after sleeping again for a short time awoke again very restless. 11 a. m., 5 dr. 9 p. m., had a dull colic – like pain in left iliac region relieved by micturition. 11, 5 dr. 31st. – After going to bed had rheumatic-like pain in left elbow, aggravated by motion. Awoke between 2 and 3 a. m.; was very restless remainder of night January 1st, 1883. – woke about 2 or 3 a. m.; was very restless reminder of night 10 a. m., after walking a short distance a dull aching pain in lumbar region, worse on right side, aggravated by motion, taking a deep breath, or sitting up straight. This pain passed away between 11 and 12 a. m. 2nd. – Awoke about 2 a. m., but was not as restless as for the past 3 night. 8 a. m., sore pain in lumbar region has passed away. 3rd. – awoke about 2 a. m.; was restless for a little while, then went to sleep again, but awoke at 5 a. m and was very restless until morning. Sore aching pain in lumbar region commenced about 5 a. m. and continued until about 10, when it gradually passed away. 8 p. m., sharp stinging pains beneath sternum at bout 3rd rib, which radiate in all directions for a circumference of about 4 in. 5th. – Pain in back scarcely noticeable. 6th, 10:15 p. m., took 40 dr. 10:45, felt very sleepy. 7th, 11 a. m., took 40 dr; 4:30 p. m., took 16 dr. Felt sleepy afterwards for some time. 6, dry, suffocation sensation in throat, and colic – like pains in right umbilical region, which come quickly and pass off slowly. 6:40, while at stool had a sore, burning sensation at the anus during the passage; this sensation I have had for about a week but have neglected to make a note of it before; 2 stools to-day 40 dr. 12:45 p. m., had uneasy feeling in abdomen for some time, and on going out in open air had colic, – like pain in abdomen, increased by walking; sleepy feeling when sitting down 4, had pulsating earache on left side with heat in ear, only lasted a few morning 4:30, took 40 dr. 7, after eating had sore, aching pain in middle hypogastric region, which came on gradually and passed off quite suddenly, aggravated by sitting up straight; feel sleepy during pain. 11, took 40 dr. 9th, 12 morning, took 60 dr. At times I have a dull aching pain in hypogastric region, with feeling of fulness and desire for stool, relieved by stool. 11 p. m., took 60 dr. Upon coming into house after a walk saw imaginary grey – coloured spots about 3 in square, in different parts of room; had 2 natural stools to – day. 10th, 9 a. m. was quite restless last night toward morning 11 a. m., took 80 dr.; 4 p. m., took 80 dr. Had a dull, heavy pain in head, more marked in vertex; feeling of fulness with dull pain in hypogastric region, with desire for stool. 8, dull headache, commencing in vertex, extending down to temporal region; full feeling, with dull pain in hypogastric region, causing desire for stool. 10, took 80 dr. Headache still continues, ameliorated by waling in open air; see grey – coloured spots about 3 in square, after coming in from a walk. 10:20, dull pain and sensation of fulness in hypogastric region, mostly right side, with desire for stool; during stool I had colic-like pain in right hypogastric region, which only lasted a moment; the dull pain before stool continued after stool, but the full feeling nearly disappeared; have had 2 natural stools to – day; headache has nearly passed away, there being only a slight dull feeling in vertex on right side. 10:40, sore, aching pain in lower part of abdomen causing me to hold my breath, lasting only a moment, passing off into a dull ache; feel sleepy during the pain. 11, pain in right nipple; came on slowly and increased to a sharp pain, then gradually passed off (I had this pain every 3 or 4 morning for a number of times); sore pain in lower part of abdomen causing me to hold my breath; headache all disappeared. 11th, 9:30 a. m., had dull aching pain in hypogastric region all night, whenever I was awake; until after 5:30 a. m. when in awoke I had the pain; I soon went to sleep gains; after that time, whenever I would be awake, I did not feel the pain. After I arose, when coughing, there would be a sore pain in hypogastric region; also when taking deep breath, but not as marked. 7 p. m., took 80 dr. Slightly thin stool of brown colour and offensive odour; with tenesmus and heat a anus after stool. Had urine examined at the laboratory; sp. gr. 1022 there was nothing abnormal except quite an excess of earthy phosphates. 1:30 p. m., intermittent colic – like pain in lower part of abdomen while eating; would come at intervals of abut a. m. 1:40, sharp shooting pains in left nipple come suddenly and pass off in a moment, leaving a sore feeling. 6, have had a sore feeling in hypogastric region all afternoon, aggravated between 5 and 6. 6:30, colic-like pains while eating, causing me to hold my breath; worse when commencing to eat, aggravated by sitting up straight or leaning back; they cause a sleepy feeling; sharp pain in right nipple. 7:10, sharp pain in right nipple, lasting about halt a. m., then passed off, leaving a sore feeling; also sharp pains in region of right kidney which left a sore feeling; uneasy feeling in abdomen followed by colic causing a desire for stool; tenesmus during stool with only a small passage. 11, took 80 dr. Sore feeling all through abdomen, aggravated by coughing or being in a warm room; feel better in open air or while exercising. 12th, 9:30 a. m., had an examination by Professor Doing of heart, lungs, liver, and spleen; all organs wee normal except the heart; there he found the are of cardiac dulness normal; movements of heart could not be seen by inspection; by palpitation heart could not be felt beating as hard as normal against the chest walls; apex in normal position; no material or tricuspid regurgitation; all sounds normal except being somewhat weak; pulse very weak and easily compressible; when hand was extended above the head the pulse was slightly diacrotic. Professor D – also took a sphygmographic tracing of right radial a which was as is here shown.[*RIGHT RADIAL – TRACING TAKEN BY Dr.DOWLING*] 12:30 p. m., took 80 dr. 1, sore feeling in hypogastric region, with colic – like pains, which commenced soon after beginning to eat, coming at intervals of about 1 morning and lasting about 1/2 morning; pains continued for about 10 morning 6:30 p. m. took 160 dr.; 11, took 220 dr. Face has a pinched ok 14th, 9 a. m., took 240 dr.; 1 p. m., took 280 dr. Feel very weak; head feels dull; face looks pinch, and very sallow; pulse very weak; when holding my arm above the head it was imperceptible; my hand turned pale, became numb, and soon went to sleep. 5 p. m., too 280 dr. Eructations of fat. 8, felt very faint upon having gums touched lightly with point of a knife, so that i had to lie down; feel better in open air 11, took 280 dr. 15th, 9 a. m., 280 dr.; 2 p. m., 280 dr. 4, dull aching pain in hypogastric region, with dull feeling in head; eructations of fat since dinner. 7, dull aching pain in hypogastric region wit dull feeling in head, relieved by stool; 2 stools to-day. 16th. – After exercising enough so that I perspired freely, my face was of a smoked colour, and remained so all day 6 p. m., took 280 dr. Very dark line under eyes. 8 sharp aching pain in left nipple. 9, tenesmus during stool, with inactivity of rectum; 2 tools of natural consistency; pulse, while sitting, 77; temperature 97.1/2 o; my temperature before taking Convallaria was between 99o and 100o. 11, took 280 dr. 17th, 12 morning, took 280 dr.; 6 p. m., 280 dr. Have had 2 stools to-day, and there was an uneasy feeling in lower part of abdomen for time before each stool; stools slightly thin and of very offensive odour. 9:30 p. m., examination of heart and pulse by Professor J. W. Dowing; heart – sounds feeble; pulse compressible, and remained compressed for a few after compressing it; holding my hand above my head, the pulse was very feeble, being scarcely perceptible, and very compressible compared with a very anemic female, her pulse was a great deal stronger than mine. On auscultation anemic murmurs were heard over jugular veins; pulse 76, temperature 98 2 stools to-day; stopped taking med. 18th. – Have had a dull feeling in my head all day, getting gradually worse until now at p. m. I have a very dull headache with a sleepy feeling; pulse 79, temperature 98.3/4o; only 1 stool to – day. 19th. – After breakfast felt very dull and sleepy, as if I had not slept any during night; pulse 75, temperature 98.3/4o. From January 19th to 28th had only 1 stool each day. ( N. A.F. of hours, May, 1883.)