10. E. E. HOLMAN. Took 8 doses of 3rd trit. at 2 hours intervals from 7 a. m. After dose at 11 slight pain in left temple; which after next dose increased much and rapidly extended over top and sides of head, continuous, very excruciating in character, but dull. At 2 feeling of “goneness” in stomach, and general lassitude. After dose at 3, with these symptoms hard sensation in stomach, as if something foreign were these with sour and bitter eructations which relieve it. After dose at 7, symptoms all increased; lungs and throat feel raw, as if scraped; watery discharge from nose. Was kept half awake all night, and in morning felt tired, cross, sleepy, mouth having peculiar feeling as if painted or coated over with something, and tasting as he remembers it doing in measles.
Has tried drug since, with similar results, but no new ones. A room – mate took one dose, which caused a “terrible” headache similar to that described. ( Ibid.)
11. S. S. ALDRICH, aet. 40, in fair health.
11a. Took 2 powders of 1st trit. before dinner (of milk) on Tuesday; felt slight stimulating effect on brain and urinary organs. On Wednesday 3 powders before breakfast; effect as on previous day, a little stronger. On Thursday, 4 powders at same time; general headache, as if in brain, with contraction of genital organs.
11b. On another occasion took 5 powders at 1 hour intervals. After 3rd, symptoms of flatulency and slight stimulation in front brain, which after 5th increased to a slight headache. (Ibid.)
12. a. Mrs. SHITCOMB, M.D., took a gr. of 1st trit. on November 19th 4 times. Between 6 and 7 p. m. had pain in left side, followed by dull, heavy ache in splenic region. 20th.– Same doses. From 4 to 6 p.m. heavy pain and pressure in left ovary, also in bladder, with frequent urging to micturition but scanty result; much flatulence; tendency to rush of blood to head; cold feet; dull pain in region of kidneys, extending to scapula. 21st. – Same doses. From 1 to 5 p. m. pain in iliac region and sacrum; pressure in bladder; same desire to urinate day and night 22nd. – No medicine, but bladder symptoms continued, with similar pressure in rectum.
12 b. December 3rd, took 4 gr. before breakfast. At 9 a. m. dull pain in splenic region; in left lumbar region colicky pain, with a good deal of flatulence. 7th. – In evening 4 gr., repeated on morning of 8th. At noon of latter day, splenic pain again; severe pain in left side of head, in temple, ear, and down neck, sharp and lancinating; sick feeling in stomach. M. evacuation lumpy with mucus. 9th and 10th. – Icy cold hands; chill if she leaves fire; p. m., painful pressure to urinate.
12 c. January 16th, took 1 gr. of 2nd trit. at noon; 2 p. m., excitement in system generally; evening, unusual chilliness; slight splenic uneasiness. Repeated dose on going to bed and next morning. 17th. – At noon, some uneasiness in stomach; at 4 p. m. dull pain in left parietal bone; at 6 heavy, dull pain in stomach; some pain in region of bladder; passes urine more frequently than usual and more of it.
12 d. April 17th, took at noon 1 gr. 3rd trit. 5 p. m., faint, sinking feeling in stomach; sense of confusion in occiput. At 5:30 2 gr. At 8:30 dull pain, quite severe by spells, in region of spleen and left ovary; pressure in bladder; desire to urinate, but little is passed; faint feeling in stomach; general depression; pulse 80, weak. At 9:30 2 gr.; during night pressure on bladder with scanty result as before; pain in both ovaries; from 5 to 6 a. m. sinking feeling and prostration; eructations. At 7 a. m. 2 gr.; between 11 and 12 dull splenic pain; at 2 p. m. irresistibly sleepy; some pain in right hypochondrium; several times during day itching, on arms especially, no rash or redness; sinking feeling by spells during day; constipation; frequent tasteless eructations and some flatulence A 5 p. m. 6 gr. In 15 minutes dull pain in frontal region; lids so heavy she could hardly open eyes, sight dim, but no pain; same splenic pain, also in small of back and stomach; empty eructations; very depressed Pains passed off in 1 hour, but depression lasted into next day, and for several day. there was thick white mucous sediment in urine, no change in quantity.
12 e. December 27th, 4 g. r of 1st trit. on retiring, and again on 28th, 1/2 hour before breakfast. Between 10 and 12 a. m. splenic pain; at 12 transient roaring in left ear, followed by ringing in right; very chilly though near fire; very cold feet, hands look purple, shrunken, and cold, very cold feeling in back between shoulders; same bladder symptoms; dull pain in left iliac region. Took 8 gr. on going to bed; on rising next morning felt nauseated, dull pain in right hypochondrium. On 29th, 16 gr. No perceptible symptoms that day, but next morning severe constriction of sphincter ani; though stool was small there was sharp pain at first attempt to pass it, and difficult relaxing of muscle. (Ibid.)
13. Three persons proved under direction of Dr. Whitcomb.
13 a. S. M.W. -, a young man of 18, took increasing doses of 3rd trit., till by 4th day he had consumed 47 gr. That day he had (for first time in life) piles, protruding half an inch, and very sore; they troubled him about 3 days. No other symptom. [It should be mentioned that for 10 days before proving S. M.W. -, ordinarily in good health, had felt unusually depressed and weak. – EDS.]
13 b. W. B.W. – took 1st trit. for 3 days in November, with no symptom save bring pain along urethra. In April took for 4 days 3rd trit. in large and increasing doses, without any effect. On December 28th took 4 gr. of 1st, morning and noon; very cold feet; in evening unusually depressed. At night 8 gr. Had to rise to void urine twice (unusually), a quantity passed. On 29th took 8 gr. morning and night, with same result during the night, but no other symptom.
13 c. T. A. HAMMOND, a young man of 23, of good health, fleshy, eats a good deal of rich food. Took powder of 3rd trit. at 10 p. m. on April 18th. Slept well. 19th. – At 5:50 a. m. another; at 6 weary feeling in small of back. At 7 repeated dose; pain increased, urinates. 8, dull pain in or through temples; also dull darting or running pain in left side, especially in small of back. 8:40, sneezing, with stringy transparent mucus from nose. 9:15, full or pressing sensation through bowels; extremities cold; pain through temples. 9:40, throat sore on 1.side; sharp pain in or through 1.temple. 10.30, pain nearly gone from temples, but quite severe in left cheek; soreness in throat increased 11:35, face, throat and side all better, but not quite free from pain. At 1 p. m. another powder; same pain in head; throat quite sore. 3, very sore across bowels, especially lower part; frequent sneezing. 4, pain in bowels subsiding, in both temples quite severe; throat better. 5, throat and bowels well, some pain in left side. 6, this also gone; occasional pain still in left temple.
On another occasion took same at 1,2, 3:10, and 4 p. m. At 2:30 languid feeling; pain through temples, changing in 25 m. to back of head. At 3:40 this pain more severe; sense of weight in stomach; thirst, which water does not appease. 4:10, pain more severe, extending to back of neck, like neuralgia (worse right side of head and left of neck). 5, sick all over; pain same, also (slight) in right arm. 6, same; little appetite; nothing tastes good; pain rather less. 6:30, less sick; appetite returning. 9:20, pain almost gone; feels thirsty and sleepy. (Ibid) [*The above provings(3-13) were communicated to Dr. Wesselhoeft by others. In the remainder, made under his own superintendence, the provers first took (unknowingly) blank powders, and noted their symptoms while doing so. Only those appearing for the first time while the drug was being taken will appear here.– EDS.*]
14. a. Mrs. FLORA H. STANFORD, married 13 years, two children, health fair. Took blank powders from October 29th to November 26th, a long array of symptoms being recorded. From November 29th to December 4th took gr. doses of 1st trit. 3 times a day. In night of 30th felt cross all the time, and had slight hacking cough, raising some white mucus; throat slightly sore. That afternoon loose stools with tenesmus; next morning gushing watery evacuations, with same. Dec. 2nd.–Legs tired, especially calves; abdomen bloated all evening. 3rd. – Same bloating in evening; can bear no pressure on thyroid gland, which feels tightened. 4th. – Feet cold in warm room at noon; 1:30, burning of fauces, with desire to cough. 8th. – For last few day continuous tingling in left Scarpa’s triangle, seat of old abscess.
14 b. From April 2nd – 20 took 1 – 3 doses daily of 2nd trit. On 7th same feeling deep in sciatic notch, while standing and walking, more on right side than left, extends across sacrum. 8th. – Thirst alternating with slight salivation; frequent desire to micturate after even slight exercise; pressure between scapulae, this last repeated next day., with soreness in throat and tickling causing cough. In evening so tired in hips and sacrum she had to lie down, which relieved. 10th. – Pressure in sacral region continues, though slight; urine light, nearly colourless, urging to micturate almost constant. 17th. – 11:15 a. m., secretion of viscid then watery saliva; 2 p.m., alternate dryness of mouth with salivation; in evening pressive pain in epigastric region. 18th. – Again dryness of mouth, with thrust alternating with salivation. 20th. – After getting up pressure returned between shoulders. ( Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.