Schreter. [Symptoms omitted, as of dubious origin, and at the best a mere replica of those of Nenning.- EDS.] (Ibid. ii.)
9. a. April 19th, nine young men of different ages, heights, and constitutions, took at 8 a. m. 5 centigr (1 gr.) of powdered C. mixed with sweet almond power. After 2 hours the pulse was slower by a few beats. In 5 the urine was increased, one felt some nausea. At 10 a. m. they took another similar dose. At 12, noon, the pulse was slower in some and quickened in others, stationary in most. All had great urging to urinate, smarting, more or less severe, in urethra, with a feeling of constriction about prostate. They took a third similar dose. At 6 p. m. the pulses of all water quicker. The urine was abundant, the smarting in urethra had increased in those who had drunk little. One had slight colic and itching at anus with tenesmus. All complained of general weakness, and they perspired profusely. Next morning they stated that in the night their pulses were very low and they felt very weak. The smarting in urethra and almost ceased in the evening, but one of them had been much teased by it in the night and some drops of blood issued from his urethra. Another felt extreme prostration and intense cold during night, and could not warm himself by heaping on bed clothes. They all sweated profusely till next day, when they felt quite well.
9b. April 21st, seven young men took 1.1/2 gr. to 2 gr. of powdered C. between 6 and 8 a. m. At 10 a. m., pulse slightly slower, in two it was slightly quicker, but evidently softer than before. Another 1.1/2 gr. was given to each. At noon the pulse was still slower. A third dose of 1 gr. to some, of 1.1/2 to others, so that each had taken 4 gr. At 3 p. m., pulse of all considerably slower, and this lasted till next day. They all drank copiously and thus escaped the distress in the urinary apparatus which they had before experienced from a smaller dose. Two only complained a little. All had copious urinating and sweat. In the evening they all complained of extreme debility. This continued during night. Some had increased appetite, others diminished, and some had copious motion of bowels. (Giacomini, Traite phil. bet experim. de Mat. Medorrhinum et de Therap., translated in Encyclop. des Sc. Medorrhinum, 2nd div., Mat. Medorrhinum et. therap., p. 149.)
10 a. November 14th, 2 drachms of 3rd dil. 4 times a day. Loose stool, urine 33.1/2 oz. – 15th, 2 drachms of 2nd dil. 4 times in the day. Urine 30.1/3 oz. – 16th, 2, drachms of 2nd dil. twice. Emission at night Next morning every weak, must lie down soon after rising from bed, fell into a restless, unrefreshing half sleep. At night many vivid confused dreams. Woke with feeling of hunger. Urine 34.1/2 oz. – 18th, 25 dr. 1st dil. Urine 351/2 oz. – 19th, twice 30 dr., once 50 dr., 1st dil. Could not sleep at first on account of excitement, thereafter vivid, confused dreams. Urine 48 oz. At noon, having urinated 1.1/2 hours previously, very urgent call to urinate. – 20th, morning and evening, 50 dr., 1st dil. At 11 p. m., m very painful throbbing pain in right of spine, where the eleventh and twelfth ribs are attached, disappearing from intervals, but recurring on any movement and aggravated, extending to right thigh in single jerks. At same time burning anteriorly in urethra as though a drop of urine remained. Urine 39.1/4 oz. – 21st, 3 times, 50 dr., 1st dil. After the first dose, morning slight nausea with flat taste and dryness of throat. Urine 34 1/4 oz. Next night very restless, long of falling asleep on account of anxious thoughts. After short sleep very bad nightmare, quite unusual. During the proving of dilutions the sp. gr. of the urine varied from 1005 to 1034. The urine was often when first passed turbid and colorless, often depositing a fine white sediment, and the surface was covered with a fine glistening skin.
10 b. November, 22, 9:30 a. m., 6 dr. of tinct in water. Immediately flat taste like sweet cheese. – 23rd. Urine clear at first, soon became turbid. He looked very ill, m eyes dull, surrounded with dark rings. – 24th, 7,9, and 11 dr. After last dose, 8 p. m., frightful headache, aggravated at any movement, pressure on right vertex alternating with painful throbbing. No appetite for supper. Pulse quick and full. Head burning hot. Urine 42 oz. That passed in afternoon and evening clear as water, sp. gr. 1026 to 1023, but the dark morning urine was only 1014 and 1015. – 25th, morning 15, evening, 20 dr. Urine 33 oz., very colourless but of high sp. gr., froths when passed. In night many confused dreams. Emission without drams. – 26th, morning 18, afternoon 22, evening 25 dr. Urine 43.1/3 oz., passed at only 3 times, clear as water, sp. gr. 1028 and 1020 – 27th, morning and evening, 30 dr. No stool. Urine 35 oz., somewhat darker than yesterday. – 28th, morning 40, afternoon and evening 50 dr. During day much inodorous flatus. Urine 35 oz., colourless, turbid when passed. Temperature on an average 0.2o lower than normal.
10 c. November 29th, 4 times 2 gr. of 2nd trit. Unusually much flatus. Urine 59 oz. at 5 times. – 30th, 4 times 4 gr. of 2nd trit. Urine 32.1/2 oz. – December 1st, 4 times 10 gr. of 2nd trit. Great weakness in sacrum with a peculiar pressive pain in region of last ribs posteriorly when sitting. Urine 35 1/4 oz.–2nd. No med. Urine 35oz. – 7th, morning, 20 gr. of 2nd, evening 5 gr. 1st trit. Urine 38 oz. – 8th, morning and evening, 5 gr. 1st trit. Urine 34 oz., – 9th, morning, 5 gr. of 1st trit. Urine 37 oz., sp. gr. varying between 1018 and 1039, average 1025.7, always dark coloured.
10 d. December, 9th, evening 1 gr. of powdered C. rubbed up with milk sugar. After 1 hour peculiar pain when urinating as through it was impossible to pass the urine, with disagreeable pressure in vesical region. – 10th, at midnight 1 gr. 3:30 a. m., woke with urging to urinate. A few oz. of urine was passed, after which there remained a very painful burning in urethra, could not remain in bed, was somewhat relieved by sitting. Must urinate every 2 to 4 morning, with almost intolerable pains. Much relieved by drinking rapidly 3 glasses of cold water. This caused copious micturition and relief of pain. Slept pretty well, but each time he woke was in profuse sweat. All next day micturition was painful and there were violent renal pains. The urine passed at night continued no albumen, but was full of mucus; the following days the urine contained much. IN the night of the 11th an emission. For 2 days there exuded from urethra a viscid, colourless fluid – prostatic fluid. Next night an emission. During this proving, every morning immediately after rising very strong and lasting erections, quite unusual. The smegma preputii, which used to be plentiful, ceased entirely. After the cessation of the proving it returned as before. Since the beginning of December he often felt during day, but especially in evening when sitting, a sensation in left side of lumbar vertebrae, on a spot the size of a hand, as if he became cold there and got goose – skin, and also there he felt a formation that was very violent and tiresome. This symptom only disappeared towards the end of December (BAHR, Z. f. Hom. Kl., iv, 121,133.).
Poisonings.
1. A man, aet. 21, from his boyhood subject to epilepsy, took overdose of tinct. Immediately burning in lips, tongue, palate, in a few hours the m. m. inflamed and swelled, and salivation ensued. He had occasionally cutting pains in stomach and umbilical region. After 3 days, at 11 p. m., he had violent convulsions and furious delirium. The convulsions sometimes ceased, but not the delirium, the fits of the former often lasted hours, or assumed the forms of opisthotonos, emprosthotonos, and trismus by turns. His expression was full of terror and despair, his hair stool on end, his eyes were staring, sparkling, convulsively distorted, pulse and heart normal; the abdominal muscles became tense at the slightest touch. The convulsions were sometimes general, the head drawn back, they terminated in syncope and stupefaction. There was constriction of the fauces that occurred at the mere sight of water. After 8 hours the attacks were less violent. He now complained of violent pains in palate, which was observed to be inflamed; by – and – by he was able to swallow some oil, later consciousness returned. (GIULIO, Mem. de. l’Acad. de Turin, 1802; from Wibmer.)
2. A strong girl, aet. 15, swallowed about 8 gr. of C. Powder; after some hours she had acute pains in hypogastrium, with burning and itching of genitals and constant urging to urinate, which she could only do with great difficulty and by drops. After some moments she had violent convulsions and distortion of limbs, she screamed and lost consciousness. Next day complained of pain in urinating and shooting in urethra, urine red and covered with small black skins. (PIQUOT DE LA HOUSSETTE, in Orfila, op. cit.)
3. A young man swallowed 3j of powdered flies. He soon felt burning pain in throat and stomach, later in hypogastrium, with great priapism; voice weak, breathing labored, pulse small, contracted; thirst great, but oesophagus so contracted he could not swallow a drop. Soon he had a horror of liquids, the pain increased, he had tenesmus of bowels and strangury, but with the exception of a few drops of blood he passed nothing from urethra of rectum. Oily injections and other demulcents were given. Next day still complained of pain and heat in bowels; had occasional priapism, and difficult micturition. for several months had some difficulty of swallowing and irritation of stomach. BIETT, in Ibid.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.