2 c. Nov 19th, 11 p.m., 10 dr. of 6th dil. soon scraping in soft palate lasting 1 h. In forenoon, pressive pain in left parietal bone rather external; tearing in left shoulder-joint. – 20th. On waking in m., and lasting forenoon, a drawing- tearing pain in right arm, which, after rising went into right wrist.
2 d. Nov. 26th, 11 p.m., 5 dr. of tinct. for 1 h. afterwards scraping in palate. At n. in bed strong heart’s beats and pulsation in upper part of chest. The pulse in the arm beat hard and quick to the fingers. The heart’s beats and pulsation in chest were stronger, more audible and perceptible, when lying on back than when lying on side; at same time anxiety and restlessness. After 1 h. these symptoms subsided and he fell asleep. – 27th, 8 a.m., 5 dr. Scraping in palate, pressive pain in upper part of right chest, oppressed breathing, increased strength of heart’s beats, and, when walking, pulsation in chest and anxiety, lasting all forenoon; also pressure in left parietal bone. Woke in m. with violent pain in right knee, extending from patella to outer side of leg; the slightest movement increased the pain; subsided after 1 h. Soon afterwards numbness of left arm and tiresome prickling in little finger for a short time. Lecherous dreams and erections in sleep. – 28th. On rising, m., pressive pain in left parietal bone. During day occasional pain in muscles of upper arm, thorax calves, and soles. – 29th. Last n. the first half sleepless on account of afflux of many thoughts; later uneasy sleep. In m., even before rising, intolerable pain in lower part of dorsal muscles on right side, extending to glutei all d. Dec. 1st. Transient tearing pains in joints, sometimes shoulder, sometimes elbows, sometimes in fingers, chiefly on right side. Dyspnoea when walking especially going upstairs, when there is also palpitation. – 2nd, 3rd. Painful weariness and heaviness of arms, and generally discomfort; drowsiness as after a severe illness. Restless sleep. On both d. empty feeling in stomach with unaltered appetite and normal stools. All the functions remained undisturbed during proving, except that the urinary secretion seemed rather scantier. (HENCKE, A.h. Z., lxxxvi, 173.)
3. Nov. 1st, 6:30 a.m., 5 dr. tincture. All day pressure in forehead now and then, more frequently in room than in open air; tearing through left arm. – 2nd, 9 a.m., 10 dr. 4th, 9 a.m., 15 dr. Yesterday and to day some pains in joints of no peculiar character and not unusual; jerking-tearing in forehead and limbs. – 5th, 9 a.m., 15 dr. Palpitation of heart when standing and sitting; anxious sensation in heart; short breathing; little pain in limbs. – 6th. Same heart symptoms – 7th, 6:30 a.m., 15 dr. same symptoms as on 8th and 9th. – 10th, 6:30 a.m., 20 dr. seems to have for some d. past a marked restlessness and hurry in what he does; seems always to come too late, never at right time, and the day seems not long enough for his work; at same time uneasiness and oppressed feeling and oppressed feeling in heart. 11th, 6:30 a.m., 20 dr. Same symptoms; the palpitation and oppressed feeling in heart felt also when sitting and lying in bed at n. – 12th. Same state. The palpitation consists of small irregular beats, with need to breathe deeply; this state is excited by any little emotion or active thought. Breathing the open air is very beneficial. towards evening some violent, but transient, pains in limbs. – 13th. Same symptoms. The palpitation worse when lying on back. – 14th. 9 a.m., 20 dr. when moving rapidly there occur quick, short, irregular heart’s beats; some severe stitches in upper part of right side of chest. – 15th. 7 a.m., 20 dr. Quick walking does not bring on the palpitation, but sudden movement, stooping, rising quickly for chair, and emotions do. – 16th. When moving in bed, m., small, quick, irregular heart’s beats; this also occurs during day at beginning of any movement, as stooping, rising turning round, but not in walking. At same time an anxious feeling in chest rising up to throat. – 17th. Same symptoms, but milder. – 18th. symptoms subsiding. – 19th, 4 p.m., 30 dr. At 5 p.m., some pains in knees and forehead; need to breathe deeply, with some irregular heart’s beats, which occur under the same conditions as before, with feeling of pressure and weight in cardiac region. At 5:30 p.m., coldness in back, and icy cold hands of 1/2 h., though face and head were hot. The pains in various joints, forehead and head return. In evening constant pressive pain in left side of forehead, lasting till he went to sleep, and felt on waking twice in n. – 20th, 6:30 a.m., 30 dr. Irregular heart’s beats on moving suddenly, all d,; slight pains in limbs and head only in m. On waking at n. and changing posture the same heart symptoms. – 21st. Same heart symptoms, and also many strong beats on walking quickly in room, with oppressed breathing and deep inspirations. – 22nd. At 5 a.m., same heart symptoms when lying on back after moving; also after rising, when walking quickly in room. The heart symptoms occurred frequently to-day; on commencing to walk are sometimes so severe he must stand still and breathe deeply several time; the same when going slowly upstairs, and even going down stairs. On waking in m. and changing posture the same heart symptoms. – 23rd. Same symptoms under same conditions. During day heart symptoms slighter. 24th. No more heart symptoms, but drawing in fingers, toes, knees and ankles. Later the heart symptoms recurred, and sometimes very severely, so that he must stand still and breathe deeply, whereby the heart – symptoms were relieved; in e. any sudden movement while seated sufficed to bring on tearing beating of heart. – 25th. Heart symptoms on rising and all day – 26th, 27th, 28th and 29th, same symptoms. (LEMBKE, N. Z. f. h. Kl., xii, 2.)
4 a. In Aug., 1887, I strongly inhaled a recently prepared tinct. (I am very sensitive to medicine.). Immediately thereafter, I drove to see patients. On leaving house of first, I found difficulty in crossing side-walk to carriage. In 10 m. more vertigo had increased, there was constriction about chest and stomach, pain in heart and head. Getting in and out becoming increasingly difficult, and nausea threatening emesis, I drove home. Vertigo was now great, causing me to reel and stagger, and I threw myself on a sofa. I had violent pain in head, chest, and stomach. Head full as if congested; great weight on vertex, pulsation and pressure outwards in temples, ears, and eyes. Objects not clearly seen; mucus in nares and throat; very thirsty, satisfied with small quantity at a time; profound nausea, lay for hours with basin beside me, retching many times, with copious discharge of mucus. Terrible pain in stomach, with pressure inwards; constriction of scrobiculus, extending to hypochondria and as high as fifth ribs, as if encircled by hot iron cincture, pressing more and more from h. to h., till respiration was most difficult and distressing. Some cough, with mucous expectoration, greatly aggravated my suffering; and I had attacks almost approaching suffocation, with hard and painful beating of heart, which felt as if compressed violently, as violently struggled to burst its bands; I could not suppress a groan, so great was my distress. Pulse was very irregular. Severe pain in spine, worse in lumbar region, pressing down glutei muscles to lower extremities; tearing pains in shoulders and arms, worse at first in joints, after 24 h. worse in long bones.
4 b. Symptoms increase for 12 h. I now remembered inhalation of C., and found its pathogenesis a perfect picture of my case. Ipecac., ver. vir. and camph. were taken, but without relief. A most miserable n. was passed, not a symptom disappeared, though nausea and constriction were less distressing, and heart struggled less violently. Tongue next m. coated thickly white; 3 mushy motions during forenoon, with pain. N. found me still in bed, unable to raise head for vertigo; symptoms same. Had a few h. disturbed sleep scared with dreams; next d. was able to leave bed for a few h. Bone pains continuing severe, took eupat. perf., with relief. The 4th m. found me relieved of all severe suffering; but I was well in no part affected till 10 d. had elapsed, and remained weak for several weeks, with frequent attacks of palpitation. (E. CLARK, M. D., Un. St. Medorrhinum Inv., April, 1879.)
5. Dr. BURT proved 3x dil. In doses of 100 to 500 dr. it caused some umbilical and hypogastric pains, with constant dull pain in cerebellum, ceasing when drug was omitted, but returning as soon as its use was resumed. He then took 600 dr., and in 4h. had dull frontal headache, with flushed face and slight pain in bowels; then soft stool, followed by quite severe pain in hypogastrium. (West. Hom. Obs., iii, 239: from Allen.)
6 a. Dr. FITCH took during some d. from 7 to 20 dr. doses of tinct. On 1st d. were observed. impulses to do something facetious or almost grotesque, which could be repelled; slow in making up his mind to action; and deliberate in carrying it out; at times during d. pressure in occiput, not severe, and relieved by quick exercise or mental activity; on retiring, this feeling amounted to heaviness and pain, with sensation as if brain were grown fast to skull, increased by lying on back, instantly relieved by turning on side so that occiput did not touch pillow; after 1 h., for some m. soapy taste; stool was followed by blood (from piles); slight priapism in evening; after retiring, and before going to sleep, drawing pain for 10 or 15 m. in left axilla and neighbouring front of chest. On 2nd d. woke feeling splendidly; slimy, weedy taste; appetite better than usual; sensation of something disagreeable in stomach; a difficult, hard stool; afterwards fluid blood from anus; muscles do not accurately obey will (as in croquet-playing). On 3rd day, soreness of abdomen, with distension; motions hence forward loose and mushy, and no bleeding. Without date, – accumulation of mucus in throat (immediately); on retiring, some unsteadiness, almost amounting to staggering, a reeling sensation.
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.