12 b. 27th June, W – took at 8 a.m., 1/2 h. after (milk) breakfast, 200 dr. of tinct. 2 p.m., while walking, shooting pains in coccyx; after dinner, slight vertigo, distension of stomach, urging to stool, soft motion. While walking, heaviness of lower extremities; e., twice urging to stool, but no action. July 7th, forenoon, tearing stitches in chest from behind forwards, worse from movement and deep inspiration; tearing pain in abdomen, l. side.
12 c. Oct. 2nd. – Took at 7 a.m., breakfast, 10 dr., 1x dil. About 11 a.m., slight drawing pain from temples to zygoma, especially l., extending once to left jaw. After dinner diarrhoeic stool; after 1 h., slimy stool, followed by burning in anus; frequent urination with burning in urethra. E., three slimy evacuations. Oct. 4th, and 6 following day, 10dr. of same. On 4th. – Tensive pain in temples, and soon afterwards copious soft stool. 5th. – Two liquid stools; tensive feeling in hollow of knee, later tearing pain in shins for some m. Afternoon, stool followed slight burning in anus; secretion of urine distinctly increased, sudden urging to urinate; towards noon, severe stitches in axilla, (quite contrary to habit) slept 3 h. after dinner, lively dreams; on awaking, dull stitches and oppression in chest about 5th rib near sternum, hawking of disagreeable mucus in throat; dryness of palate as if covered with tough mucus. 6th. – One h. after taking medicine, thick stool with drawing and pressure in sacrum; pressive pain in occiput with drawing in nape; noon, pressive pain in temples and forehead; e., in bed, shuddering of lower extremities, skin of which felt cold; after being warmly covered, severe tearing stitches in right knee, several stitches in left shoulder. 7th. – Vertigo; towards noon, occasional tensive pain in muscular sheaths of upper and lower extremities; slight burning with stool and when urinating; severe burning and watering of right eye; whizzing in ears; stitches in joints of little finger left hand. Afternoon, while lying, dull stitches between shoulder-blades, burning stitches left heel at insertion of tendo Achillis. 8th. – Pressure and drawing in loins and temples, especially after dinner; tearing and drawing pain forearm and foot. E., while sitting dull stitches through chest and abdomen (umbilical region); four scanty stools with slight pressure. 9th. -Compressive pains in temples, alternating with similar pains in occipital region; soon after eating, cold feeling in back extending forwards towards axillae and forearms, with simultaneous severe pressure in scrobiculus cordis; several stitches in ribs right side. At 10, cold feeling in spine with tearing pressure in back and loins (muscles), lasting whole day, better when moving. Afternoon, three fluid stools. 11th. – Without medicine. Soon after breakfast frontal headache aggravated by stooping; skin felt hot, and perspired readily. 12th. – Without medicine. Severe twitching and tearing pain in region of last lumbar vertebrae and sacrum; muscles of loins sensitive to contact or tight clothing; fulness, as from incarcerated flatus, now towards region of stomach, with urging and pressure, now backwards, more or less all d., better walking about and bending backwards, worse stooping. Pain in loins for next 3 d.
12 d. W – took on Oct.21st,, at 7 a.m., 1 h. before breakfast, 10 dr. of 6x dil. Towards 9 a.m., tensive pressive sensation in left temple; later, tearing in left knee extending to shin and foot. After dinner, severe pressure in stomach as if from a stone, recurrence of knee pain worse from motion. E., pressure in fore part of brain toward forehead and left eyeball, especially on stooping. 22nd. – This headache all d. After dinner when sitting squeezing tearing in right calf of short duration; when writing, twitching tearing in middle knuckle-joint of right hand; marked hoarseness all day; retarded stood followed by twitching and stitches in anus, 23rd, 10 dr. Profuse lachrymation, right conjunctiva reddened, lids agglutinated at outer canthus; drawing and tearing in right elbow – joint and forearm to wrist. After dinner, dryness of palate, distension of abdomen, nausea; afternoon great lassitude, ringing in ears with impaired hearing for 2 h.; e., chilly feeling in left thigh. 26th. – Without medicine. Headache somewhat less severe. After eating hiccup, and on every shock caused by it pressure in forehead, as if brain shook from behind forwards. 27th. – Without medicine. One h. after eating, stitches and pressure under sternum, worse from movement and deep inspiration; later, dull stitches in right groin; chilly feeling in left thigh. 28th. – No symptoms except fine stitches under nail of little toe of left foot.
Wachtl states that some of the symptoms continued until the middle of November. (Ibid.)
13 a. Dr. WATZKE took on May 24th, 1844, 20 dr,; 25th, 40 dr.; 26th, 80 dr.; and 28th, 80 dr., of tinct. E., of 26th and 27th, on lying down, uneasy feeling as if chest were contracted, thorax painful rapidly repeated heaving respiration. 28th. – Stool very constipated (contrary to habit); afternoon, repeated severe twitching stitches in both temples, extending sometimes over left parietal region.
13 b. June 13th, W – took at 8 a.m., after chocolate breakfast, 100 dr. of freely prepared tinct, of B. dioica. In 1/2 h. afterwards while out walking uneasy movement in stomach and constricting sensation in throat; sudden vomiting lasting 5 m., this repeated twice afterwards at interval of 1/2 h. accompanied with painful scraping and constricting sensation in stomach; vomiting at first painless, vomited matter being chocolate, water, and mucus, tasting of what had been taken; later vomiting (with difficulty) of yellow, thick tenacious bitter fluid, ceased after taking a basin of warm soup. At noon good appetite. No further symptoms except great tendency to vomiting and jaundiced aspect, both lasting a long time.
13 c. April 5th. – Took 5 dr. tinct. B. alba. Soon afterwards pressure and contracting sensation in stomach; between 4 and 5 p.m., painless twitching and contraction in left upper eyelid every 2 or 3 m., sensitive heavy feeling remaining in it; n., restless sleep, free perspiration; unusual lassitude next d. 6th. – Took 10 dr. tinct. on sugar after breakfast. After 1/2 h. sensitive pressive pain (coming and going in left eyeball, especially violent on moving it, with feeling as if eye became smaller and was retracted within orbit. After eating severe sickness as if from abdomen; anxious feeling; disinclination for food, but taste not changed. Towards e. tenderness of scalp, jerking stitches on vertex, elbows, wrists and especially severe on several spots of forehead; teeth sensitive; irritable mood, desire to be alone. When going to sleep, a feeling as if chest were contracted; chest somewhat sensitive. N. again restless; next m. sour eructations tasting of fish eaten previous n.; at noon good appetite again. The pressive pain in eyeball recurred frequently towards e. on this and following day 9th, noon, 10 dr. – Immediately twisting in umbilical region and slight sickness. After some h. pain in right temple; a tensive twitching in muscular fibres, lasting a few seconds; part very sensitive, pain recurring several times during 1/2 h. towards 8 p.m. pain recurred on same spot, lasting almost 1 h. also occasionally slight twitching in right upper eyelid; transient recurrence of pain during following 8 d.
13 d. During April, May, and June, Watzke took every 4th or 7th day a dose, increasing by 5 dr., up to (June 21st and two following d.) 50 dr. Stitches through chest, especially twitching headache (temples). During last two months a skin eruption has appeared, first on sacral region, extending to back, chest, and forearms; rash consisting of groups of vesicles, which dried up, leaving red and scaling skin.; occasional itching, especially during active movement. Eruption declined in July and disappeared during August. (Ibid.)
14. Dr WURMB took on June 3rd, 1884, at 6 p.m., 100 dr of tinct. No symptoms. 7th, at 5 p.m., 150 dr. Nausea during e., distaste for food, n. restless, sleep disturbed by exciting dreams, waking often, with chilly feeling in toes 8th. – Without medicine. In m. scanty stool. 9th. – Without medicine. No action of bowels n. restless, waking often after exciting dreams. 10th. – Without medicine. In m. scanty stool only after much straining; tearing in first joint of right thumb, and last joint of right great toe, frequently during d.; afternoon, sore throat (pressive pain in right tonsil on swallowing), at same time stitches in r. ear. 12th at 5 p.m., 200 dr. Scraping sensation in throat during e. 13th. – Without medicine. In m. edges of eyelids (especially r.) swollen and reddened. Forenoon, discharges of offensive flatus. -Afternoon, hard scanty stool. 18th, at 6 p.m., 250 dr. Soon afterwards frequent sneezing. 19th. – Without medicine, scanty stool. 20th. -Without medicine. No action of bowels. 21st. – Scanty stool; head more or less confused all d. Afternoon, pain in left temple pressing from within outwards. 22nd, 23rd, and 24th. – Without medicine. Several copious stools each d., almost diarrhoea. July 3rd at 5:30 p.m., 300 dr. 4th. – Without medicine. No action of bowels, unusual frequency of nutrition. 8th, at 8:30 a.m., 20 dr. Soon, confusion of head which gradually developed into severe pressive pain, especially in left temple, worst about 5 p.m., also sickness; over-sensitive hearing and hissing in left ear. 9th, at 8:30 a.m., 20 dr. Discharge of flatus. Afternoon severe urging to stool, but only flatus passed; rumbling in bowels for 1/2 h. 10th, 20 dr. No symptoms. 11th, 20 dr. Scanty stool frequent sneezing. 12th, 20 dr. Scanty stool; sneezing. 13th, 20 dr. No symptoms. 24th, 50 dr. 25th, 8 a.m., 50 dr. At 3 p.m., severe cutting pain in bowels, urging to stool, copious papescent evacuation and flatus; confusion of head, worse when walking. (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.