Realgar. Arsenious sulphide, Ao2S2.
For these provings, never before printed, we are indebted to Dr. Neidhard EDS.
1. Dr. Neidhard took, Dec. 30th, 2 gr. of 2nd trit. in m. A loose small evacuation during day at an unusual hour, and another one in e. General heaviness of whole body; sleeps longer, and is more difficult to rouse. Very vivid dreams. Heavy pain in forehead. Pain in bones of left upper arm, more towards m. on waking. Heavy sensation and gnawing in region of stomach. 31st. – 10 a. m. Took a powder of 1st trit. During that day and next had very little appetite, and sometimes aversion to food. Jan. 2nd. – In evening on returning home, felt symptoms of derangement of stomach, great weakness, and trembling all over. 6th. – Took another dose of 1st trit., with little or no effect. 20th. – 1 p. m., took a powder of 2nd trit. After meals indisposed for mental or physical exertion. Slight drawing pain for a short time in J. spermatic cord. Feb. 6th. – Took another powder of 2nd trit. without experiencing any effect. (Communicated.)
2. Dr. Preston, of Providence, R. I., took a powder of 1st trit., and felt for first 24 hours rheumatic pains from right shoulder down arm, as if in bone, with paralytic feeling for 3 day; also considerable pain in right hip, with lameness in leg. (Ibid.)
3 a. Dr. A. Lindsay, of Roxbury, took, Nov. 17th, 5 gr. of 1st trit., but could perceive no effect. On 19th, at n., took another dose of same. Slept better than usual; had bitter taste in the mouth on waking. Dec. 3rd, at n., took a powder of 2nd trit. Towards n. on 4th felt very cold and chilly, even before a hot stove, for 3 – 4 h. He did not sleep so soundly as usual, was restless, and had many dreams, waking often with dull pain in forehead over eyes, extending to vertex (nearly to organ of “self – esteem”).
3 b. A friend of this gentleman, to whom he gave a dose of the same trit. at n., was very sleepy before he took it, but very restless after taking it, and could not get to sleep for 2 hours, often waking with dull pain in head. (Ibid.)
4. Dr. Houard took a powder of 3rd trit. at 8 a. m. on Dec. 20th, but felt no effect till 11, when he experienced general malaise and chilliness, with pain across forehead. This pain lasted until he went to bed, when it left him during his sleep. 21st. Took a second powder of same on rising. Felt no effect until an hours after breakfast. Fulness and weight at pit of stomach; low – spirited, and no disposition to talk all day; ate but little at dinner – time; disagreeable feeling in the stomach lasted until 8 p. m., when a burning sensation set in, which increased every m., and from 10 till 9 next m. was so intense as to deprive him almost of his breath. He found no relief in any position; he lay on his back all night; could not rest a m. on either side. He rolled on the bed, sat up, and groaned incessantly. Feet and hands cold; trembling of whole body; twitching and jerking of lower extremities; anxiety and fear of death; his stomach felt as if he had coats of fur in it. Pain extended from cardiac extremity to left hypochondriac region; took nux vom., chamom., colocynth, without the least relief; cold drinks increased burning in stomach. He sent for Dr. Gardiner, who told him that he had poisoned himself. Pulse depressed and thread – like; face pale and livid; could not bear the least pressure on region of stomach. Took acon. every hours; felt relief on second dose. From that time was better. Next day very weak; much soreness over whole extent of stomach; had stool of pure bile, and urine of saffron colour. This colour continued for 5 d. The discharge of bile also continued for 5 d. Stomach still felt weak; appetite better. Whole mucous membrane lining mouth and throat much inflamed; both lips also inflamed, as well as the left side of the tongue; conjunctiva of left eye very much inflamed and puffed out. Large bluish spots appeared over epigastric region, abdomen, and thighs. Excessive thirst continued for 3 day (Ibid.)
5. Dr. J. C. Raymond, Utica, N. Y., took, April 15th, when in usual health, a powder of 1st trit., at 10 p. m. Observed no effect. 17th. – Took another powder of same. 18th. – Sensation as if a coryza were about to set in, sneezed several times during day, with tingling in the right nostril. Increased heat of head and face, with feeling of fulness and heavy dull sensation in head. Coldness of hands. During afternoon dull pains in bowels, with feeling of fulness extending across them in hypogastric region. 19th. – 5 p. m., severe continued pain extending deep into brain in right frontal region, also to right ear, very much aggravated by stooping and exercise, relieved by application of cold. Sensation of fulness and pressing outward in right ear; a snapping sound in ear corresponding to pulsations of temporal artery; sensible pulsations of arteries of right side of face and head. Scarlet redness and burning of upper half of left ear, with tingling similar to that produced by a frost bite. Ear felt hot to touch. These symptoms continued until he fell asleep at n. Sneezed several times during day 20th. – Occasional sneezing, dryness and tingling of left nostril, with thin white discharge from right nostril. Took a powder of the 1st trit. at 10 p. m. 21st. – Numbness and prickling affecting inner side of right calf, heel, outer side of foot and little to, commenced at 6 a. m., and continued more or less severe until noon of 22nd. Slight numbness of forearms and hands with heaviness; he dropped several things which he took hold of; sneezing occasionally with thin white discharge from both nostrils. 25th. – 6 a. m. took another powder. Felt nausea, p. m., no inclination for supper; during evening felt a dull heavy pain extending from pit of stomach to back, with sensation of weight in stomach. 26th. – P. m., violent itching of third toe of left foot, producing occasional pain of muscles of foot and leg. 27th. – 3 p. m., severe pain affecting inferior third of left tibia, pains commence at the lower point of malleolus internus and extend u; wards in shaft of bone. The pains are momentarily relieved by changing positions of foot and by friction with hand on affected part. They continued severe for 3 hours, after that lighter, until relieved by sleep. Took another powder at 10 p. m. 28th. – 7 p. m., a very unpleasant quick beating extending deep into left ear, with pain, scarlet redness, and heat of upper half of ears. Ear felt full with pressing outwards. 29th. – Awoke at 5 a. m. with sharp cutting pain, commencing between the cartilages of the 5th and 6th ribs, extending inwards and upwards deep into chest. Pain was so sharp that it did not admit of the slightest motion, and he was obliged to suspend respiration as much as possible. Pains continued for 1/2 h. Took powder of 1x trit. at 9 p. m. 30th. – After rising in m. felt a heavy pressing pain extending from point of os coccygis to anus, with soreness of the os; the pain is increased by efforts to evacuate bowels, and when passing water; bearing down would produce a heavy sickening sensation. (These symptoms continued 3 d.). 4 p. m., dull pain in right frontal region, which increased in severity, and became a sharp throbbing and shooting pain extending to right occiput, aggravated by motion and stooping. Heat of head and face, redness and heat of left ear. The symptoms continued until relieved by sleep. May 1st. – Sharp cutting pains in left abdominal region after each meal, aggravated by walking, relieved by firm pressure with hand upon affected part. Free discharge from nostrils, thin and white. 2nd. – Same symptoms as yesterday. Took another powder of 1x at 10 p. m. 3rd. – Discharge from nostrils less and thicker. Occasional sharp pains, which appear to affect base of heart, impending respiration. Hoarseness with accumulation of tenacious mucus in the throat. 4th. – Hoarseness, at times intolerable itching in throat; the irritation induces a short dry, expulsive cough. Enlargement of right tonsil, inflammation of throat with deep redness. Occasional pains and raw feeling. Took another powder at 10 p. m. 5th. – Symptoms as yesterday. P. m., headache similar to of April 19th, with additional symptom that pains were in whole frontal region, but most severe in r. The inflammation of the throat and coryza continued a few day longer, and passed off. Occasional sneezing during entire proving. The majority of the symptoms manifested themselves p. m. (Ibid.)
6. Patrick McNamara, my waiter, made a proving of Realgar. He was so good – natured, that notwithstanding the strongest provocation, he could never be made angry. He merely smiled. After the exhibition of Realgar, he often became cross, and showed more temper than he ever did before. On April 3rd he took at 0 a. m. 3 gr. of 3rd trit., and at 10 p. m. he took 5 gr. 4th. – Had a pain commencing in back of head (below “philoprogenitiveness”), and extending thence around sides; sometimes dull and sometimes sharp. Pain commenced about 7 a. m.; head felt much heavier than it had ever done before. He felt very well in aft. At 9:30 p. m. took 6 gr. 5th. – No effects from second dose. Did not feel the head symptoms any more. 6th. – About 1 p. m. thighs and legs felt itchy. The itching seemed to leave in about 2 hours, and about 5 the anterior muscles of the thighs felt sore in descending stirs. About 9 legs and thighs began to itch again. Head felt better to – day than it had for a long time before (curative). At 9:30 p. m. took 5 gr. 7th. – Has been very cross all d. Has been very cross all d. Has a better expression in the countenance than before; it used to look dull, but now look bright. Last n. dreamed a great deal. Most of the dreams were pleasant. The medicine seems to exert a curative influence upon him. (Ibid.)
ATROPINUM (see vol, i, p.546)
II. 12. Mr. A -, aet. 26. Of 1/2 gr. of sulphate dissolved in 15 teaspoonful of water, a teaspoonful was (by mistake) administered every 1/4 hours until 1/4 gr. had been ingested. Pulse was 145, temp. 100, respiration 42; face congested; he was extremely restless, very talkative and silly. He answered questions correctly, however, when addressed; but would soon pass into an hysterical condition with delirium. Dryness of throat, with burning; intense, throbbing headache; disordered vision and pupils widely dilated. Micturition frequent and copious. Soon after doctor had entered patient vomited profusely, complaining of loss of sight; there were slight convulsive twitchings of facial muscles with trembling of limbs. Would sleep for a few m., then wake with a start or scream, throwing himself across the bed. He would plead not to be buried alive or burned, and was calmed with difficulty. Emetics, followed by stimulants and opium, were given freely, together with cold bathing. The next day he still suffered with a sore throat, which was red and congested. Intense, throbbing headache, especially in frontal region, and scalp extremely sore to touch, ” feeling as if separate hairs were tied tightly together.” There was double vision with bright flashes before eyes, pupils still largely dilated; lids red and sensitive, feeling as if pepper had been put into them; deafness, with ringing in ears. Great thirst, but nothing tasted good, and nausea and vomiting followed every attempt at drinking. Mind was fairly clear, respiration still hurried, pulse fast but strong; restlessness still a prominent symptom, with trembling of limbs and feet, feeling as if heavy weights were attached to them. Complete retention of urine compelled of catheter for it for 2 day; and bowels were constipated, perhaps from the opium. It was a week before patient fully recovered. (B. F. Church, Publ. of Mass. Hom. Medorrhinum Soc., ix, 67.)
13. a. On Feb. 26th of this year a lad aet. 12, who though healthy was of slightly nervous temperament, was sent to me by Dr. Phillips, of Warwick, as he was suffering from defective vision, and the use of the eyes for study caused headache. It was easily recognised that hypermetropic astigmatism was the cause of all his trouble, and, in order to estimate accurately his error of refraction and thoroughly paralyse his accommodation, I ordered two or three drops of two grains to the one ounce solution of atropine to be instilled into the eyes three times within an hour on the Thursday morning, and again three times during that day, three times during Friday, and once on Saturday morning, on which day he was to visit me for correction. This would make ten instillations, spread over two days. When he was brought to my rooms on Saturday he had all the symptoms of atropine poisoning, staggering and unsteady gait, dryness of throat and tongue, picking at imaginary objects in the air, talking, or rather muttering, incoherently, smiling, and occasionally laughing outright to himself. I was able to rouse him to attention for a few minutes, so that he would answer questions and do what I told him; but he soon relapsed. The face was slightly flushed, but there was no rash; pulse small and rapid. Pupils were only moderately dilated, and responded but slightly to light. The mother assured me that she had most carefully used the drops as directed, but as the lad had seemed strange the previous afternoon she stopped using them, so that they had only been put into the eyes eight times in all. I ordered him at once to be taken home and kept as quiet as possible. Milk diet and small doses of Dover’s powder were the treatment, but throughout the day he continued to get worse, and in the evening tetanic spasms came on with delirium; in fact, he became so bad that, as I was absent from town, another medical man was called in. He at once recognised what had happened and quieted their fears, and in a few days the little patient got all right, but it was a week or two before he became well enough for me to correct his astigmatism.
13 b. The second case was that of a remarkably healthy old gentleman, named J. K -, aet. 73, who consulted me on March 5th preparatory to an operation for cataract. Being wishful to see if the cataract was mature up to the periphery, I instilled three times, in about twenty minutes, two or three drops each time of a 2-gr. to the ounce solution. The pupil dilated readily, and after finishing the examination I noticed that he spoke thickly, and did not answer questions readily. He got u; to walk and fell back into the chair and soon became almost unconscious. Paralysis was so complete that he was quite helpless, and had to be carried to the cab, his face becoming suffused, and the body covered with an erythematous rash; pulse so rapid that I could scarcely count it. I ordered the same treatment, and in a few days he recovered, but had no tetanic spasms whatever. (S. Mathews Owens, Lancet, 1890, ii, 443.)
14. I prescribed for a child of 3 mo., suffering from whooping – cough, a mixture containing gr. 1/200 of the sulphate in a fluid drachm. The mother gave the child a teaspoonful early the next m. In a few m. it turned a deep red, “like scarlet fever,”over its face and the upper half of its body; the perspiration was checked, and the skin became hot and dry. |This continued for 5 h. Next m., at my request, she gave only half a teaspoonful; the same effect was produced, but lasted only 2 h. On the 3rd m. she gave only 4 dr., and this time without any effect; but 6 dr. on the following day produced the redness, though it only lasted 1/2 hours (6 dr. of the sol. were found = 15 min., which would contain gr. 1/200 of A.) No narcotism was produced by any dose. (Sadler, Medorrhinum Times and Gaz., 1868, i, 391.)
15. A man drank by mistake Zi of a 4 gr. to oz. solution. I saw him 15 m. afterwards, at 12 m. He was lying down, being unable to stand; face was flushed, and there was intense vertigo, but he was able to talk, and said distinctly that he knew he must have taken the drug. Pulse was 140, resp. correspondingly increased. The countenance wore a peculiarly anxious expression; eyes were wide open, and he shaded them with his hand, not liking the light; pupils largely dilated. There was formication all over the body, and tingling at the end of fingers and toes; tongue was moist to sight and touch, but the man said it felt ” as dry as a chip,” and the throat seemed almost as if its sides were stuck together. Hallucinations of sight and hearing were also present, but were soon forgotten. (Sewall, M. H. Rev., xxvi, 426.)
AURUM (see vol.
II. 9. A man, aet, 66, gilder of picture frames, spare, muscular, of acutely sensitive nervous temperament. In June, 1985, suddenly and without cause or premonitory symptoms, was prostrated with pain in lower spinal column, lasting 30 m., and then ceasing. 2 day later was attached again with similar pain, but causing more prostration, profuse perspiration, and nausea. This lasted 24 h. Again, 2 day later, by similar pain, but located over the course of left sciatic nerve in the hip. This periodicity continued, pain never commencing in daytime, always ceasing at sunrise, and usually beginning after falling asleep for an hours or two. Pain worse in decubitus, relieved by standing upright or walking. This went on for nearly two years. For first 12 mo. general health continued good, but then want of sleep began to tell upon him, and under ” active treatment” in a hospital he got much worse; legs and body swelled; there was obstinate constipation; and nerves became so acutely sensitive that motion was torture, and a mere touch on the ankle knocked him down. Dr. Smith found him in March, 1867, suffering from great hypochondriacal depression of spirits, longing for death, restlessness, impatience of contradiction and irritability; there was shaking of head, stoppage of nose, jerking twitches in left buttock, painful stiffness in hip. Remission of pain in day and evening, recurrence at n., pain lightning – like, darting between hip and ankle. Could bear to pound on the affected thigh with fist, but still a slight contact when unexpected had filled him to the floor. (Heber Smith, Trans. of Amer. Inst. of Hom., 1869, p. 262.)
BAPTISIA (see vol.i,512)
I. 14. Dr. Sutherland, after taking, Nov. 18th – 22nd, 3, 4, 5, 8, 12, and 20 dr. of tinct. without effect (a frontal headache experienced on 22nd he ascribed to working in a warm room with vitiated air), on 24th, at 4:30 p. m., took 30 dr. Tendency to pressure in frontal and temporal regions, especially during and for a short time after moving about, was noticed during e. Dec. 1st, at 11 a. m. took 40 dr. Same sort of fulness in the head 3 hours after dose; it went away before 4:20 p. m., when he took 13 dr. more, but nothing followed. After waiting awhile to see if remote symptoms would appear (which they did not), on Jan. 16th, at 4:15 p. m., he took 150 dr. It left after swallowing a hot disagreeable sensation in fauces and throat, causing secretion of thick saliva with desire to swallow. At 8 p. m. took 100 dr. more in a little water. Felt a little sensitive to cold air, but this was not long lasting or very uncomfortable. 17th. – Was conscious of discomfort in left frontal region on first awakening, but it had gone off 1/2 hours later when he got up. 18th. – An abundant unformed but faecal motion at 9 a. m., with some tenesmus. During day felt some lameness and soreness in right lumbar muscles, especially when bending forward. About 3 p. m. an extremely small motion, consisting of about a teaspoonful of tenacious blood – streaked mucus. 26th. – At 11 a. m. took 350 dr. in a little water. For a short time after swallowing it throat in region of larynx was irritated, roughened as if scraped; at 8 p. m. pulse 92, temp. 99.5 o (these are the maxima noted in health). 27th. – On rising from stooping, decided but transient vertigo. No further symptoms notice; and pulse did not rise above 84 that evening, or temp. above 99:25 o. (N. Engl. Medorrhinum Gaz., xxiv, 566.)
15. G. H. I. took 12 doses of 3 – 25 dr. on as many days. After 20 and 25 dr. he had a slight frontal headache, worse in a warm room, relieved by food, cold air, and motion. No other effects. (Ibid.)