11. N. N-, medical student, age. 23, sanguine temperament, delicate constitution, troubled during past year with palpitation of heart, for which acon. gave speedy relief, since then in good health. From 14th February to 3rd March inclusive took daily, morning and evening, from 14th to 16th 10, on 17th 15, thence till 22nd 12, from 22nd to 27th 15, from 28th till morning of 4th March 20 drops. No symptoms except scraping in fauces, pepper- like smarting on lips, gradual injection of palate and tonsils; and 4th March tearing all through forearm, wrist, and fingers of right side. 5th, 24 drops. Tearing in upper arm and upper third of right thigh. From 6th to 13th daily, morning and evening on 14th and 15th only morning, 24 drops. On 6th scraping in throat, which is injected; evening, tearing in right upper arm about elbow-joint and in thigh about knee-joint; on 7th, afternoon, a sudden tearing in left knee-joint lasting 10 morning. On 8th and 9th occasional violent tearing alternately in both thighs, in right knee-joint, and right forearm. Along with scraping in throat on 9th uvula and right tonsil were much injected. 10th. – On coming into to open air 1 hour after taking medicine violent palpitation of heart, that after dinner at 3 p.m. and 8 p.m., one hour after dose, returned and lasted 1/2 hour. Next day two attacks of palpitation of heart, pulse quicker and stronger. Sleep during whole time sound and dreamless as usual. 12th, afternoon, violent tearing in right arm about elbow joint. Both tonsils and uvula very red, scraping in throat. 13th, forenoon, palpitation of heart that lasted 1/2 hour, with feeling of tightness of chest. Between 5 and and 6 p.m., tearing in left shoulder-joint. Next day at 10 a.m. palpitation of heart, hard stool after 3 days of constipation. 15th. – Only scraping in throat. 17th,5 p.m. 24, drops. After 2 hours violent and quick beating of heart for 1/2 hour 18th drops and 19th, morning, 20 drops. The 1st day in afternoon, tearing in whole left forearm, 2nd, evening, violent palpitation of heart. 20th, afternoon palpitation worse than ever with heart. 20th, afternoon palpitation worse than even with great anxiety and difficulty of breathing. Took at noon 20 drops, when it became less, but lasted slightly all days and evening; in addition tearing and formication in right arm. The next 3 days, morning 24 drops. No effect. Therefore, from 23rd to 26th he took daily, in morning, 40 drops; from 27th to 8th April daily 50 drops. 23rd. – Tearing in elbow. The next 2 days no symptoms except some scraping in throat. 26th. – In evening violent tearing for 1/2 hour 27th. – After 1/2 hour formication along left arm. 28th. – From 11 a.m. till 1 p.m. very violent palpitation of heart; transient coldness with momentary shivering, followed by heat and sweat. 29th. – Besides tearing in elbow for 10 morning a sudden, transient, but violent compressive pain in right upper orbital border. 30th. – No symptoms. 31st. – Same symptoms as 29th, but only late in evening; also pressure on left eyeball as from a heavy weight. Tearing in orbital border; this ceased following evening. 2nd April. – On going out violent palpitation of heart. 3rd, forenoon, pressive tearing pain in left orbit, like constriction, as if eyeball would be pressed out. This was repeated 5th and 6th. 7th, morning, 1/2 hour after dose violent palpitation of heart lasting 1/2 hour, with great anxiety and dyspnoea, also the pain in right orbit. After a walk of 1 hour marked exhaustion of extremities, increased on again walking in afternoon,. When at rest rigor, lasting from 5 to 10 morning followed by considerable but transient heat and rather profuse perspiration; at same time heaviness of head and a vertiginous swaying and swinging of head. 9th. – At 6:30 a.m. 70 drops. After 1/4 hours palpitation of heart and great oppression, feeling of pressure in right orbit, and heaviness of head; he feels as if tipsy, and quite unable to study. 10th, 7:30 a.m., 50 drops. Soon afterwards palpitation of heart with great oppression; all day heaviness of head, giddiness; roaring in head and ears, increased by reading; he staggers as if tipsy or as if he had a violent contusion on head. 11th, morning 50 drops. Tearing in right forearm worse than ever, lasting from 11:30 a.m. till 5 p.m., at same time continued giddiness. At 8:30 p.m. 50 drops. Tearing repeated till midnight. 12th. – 100 drops; no symptoms. 13th, at 6:30 a.m. 120 drops. From 10:45 a.m. till 4:30 p.m. constant feeling of tearing in all left forearm, hand, and fingers. This symptoms reappeared next day at same time and with equal intensity, but was limited to forearm, and lasted only till 3 p.m. At same time quickened heart’s beats and difficult breathing. The following day no symptoms. 16th. – Only the cardiac and respiratory symptoms appeared. 17th, forenoon, from 10 a.m. onwards pressive pain over whole cranial vault, as if equally compressed from all sides, the pain is sometimes concentrated with the greatest intensity in left orbit. This lasted till 1 p.m., came on next day at same hour with still greater violence, declined about noon, and went off completely during dinner at 1 p.m., but returned with equal violence about 3 p.m. In forenoon it was accompanied by tearing in forearm, great anxiety, and dyspnoea. 19th, 20th, and 21st. – No symptoms. After irregular intervals of 3,4, and 5 days there occurred occasionally during day some tearing in various parts, chiefly in left forearm, gradually growing slighter. The palpitation occurred occasionally, and at length went off completely. Even after a month the tearing was occasionally felt. (Ibid.)
12a. Dr. REISINGER took from 5th till 15th January, daily, 5 drops of tinct. 1/2 hour before breakfast. On 2nd day slight formication with warm feeling in left index and middle finger; at same time painful drawing in right cervical and nape muscles, which went off during night. 10th. – Slight transient shiver over back; shooting and tension in gastric region for several hour, very like flatulent colic after a full meal. 18th. – 10 drops, 3 times, 1/2 hour after breakfast, at noon, and at 4:30 p.m. Woke from afternoon siesta (which always made him warm) with chilly feeling all over body and cold right upper arm, left being moderately warm. the chill lasted while walking in open air and in warm room till 7 p.m., fever. From 19th till 28th daily, morning and afternoon 10 drops. No symptoms except empty eructation after each dose, and twice slight pressing headache in right temporal region. 28th, 29th, and 31st, morning 20 drops. 28th. – All days, increased feeling of warmth, exhaustion of head, small appetite; evening before going to bed, increased heat, full quick pulse. When sitting still felt beating of carotid and temporal arteries. No desire to go to bed; when he went to bed at 1 a.m. felt need to sleep, but could not sleep; increased disagreeable heat of whole body, especially of lower extremities; sweat on inner surface of thighs, over scrotum, and violent itching there compelling him to scratch till blood came, somewhat allayed by cold washing. In the half-sleep that lasted till morning, troubled with confused fantastic dreams. 29th, forenoon, sweating and itching on scrotum; in evening and through night troublesome heat, night sleepless with dreams; the following night less, but still very restless. 31st. – Momentary pain in right hip, that went off when walking in open air. From 1st till 4th February, daily, 40 drops, 1/2 hours after breakfast. 4th. – Transient slight pressing pain in right temporal region, a similar transient pain in right abdomen parietes, as from flatulence, 2 or 3 times during day. This latter came on the next 3 days in left side. 7th, evening, chilliness followed by slight arm feeling, ending at night in profuse sweat. 8th, 9th, and 10. – Daily, 40 drops, return of the periodical pains in abdomen. 11th. – 60 drops. All days very depressed spirits; evening, for 5 or 6 hours pain in cervical muscles and shoulder-joint, so that he could not move arm backwards without great pain. Sound sleep at night 12th, 13th, 14th. – No medicine. 14th. – Noon, slight griping in belly; night, sudden slight prickling in tips of fingers and toes, frequently recurring. 15th. – 60 drops. Only astringent taste and hawking of fluid saliva.
12b. 18th March. -60 drops. After 1 hour violent pain in left eyebrow, as if head were split with a wedge, lasting more or less all forenoon; frequent eructation, with taste of medicine; prickling and burning in tongue, as from pepper or much tobacco smoking. These symptoms felt equally when walking in open air, and in the room. Woke from afternoon siesta with slight transient shooting in left upper part of chest, as from flatulence; evening confusion of head, difficulty of getting to sleep; quiet night. 199th. – 80 drops in water. After 1/2 hour feeling of burning and heat in lung, not affecting breath, felt as if a hot fluid would rise into mouth, at same time constant burning and manifest swelling of tongue, as after pepper or peppermint, wilt feeling as if cold air passed over it; frequent increased secretion of watery saliva, almost like salivation, lasting 4 hours. At same time the wedge-like forcing asunder headache, worse in room than in open air. Very anxious and giddy; slight chilliness over back, with numb feeling on sacrum to lower extremities; when sitting or standing the lower limbs feel as if asleep, or as if adherent to the ground; this went off immediately on walking, but recurred at once on sitting down or standing still; lasted 1/2 hour. Frequent emission of urine as clear as water, though he had drunk nothing but the medicine. at noon felt well; evening, slightly increased cutaneous temperature; night tolerably quiet; next day no symptoms except those of the mouth. 21st. – All the symptoms of the 19th returned in the same order, only slighter and shorter. 22nd. -100 drops in water. After 1 hour burning pain in tongue, increasing every morning, with considerable flow of saliva, for hours; anxious feeling in scrobiculus cordis, with vertigo, especially in warm room; constant chilliness in back with cold extremities, even in warm room, as before a catarrhal fever breaks out, for 1 hour; depression, out of humour, very hard stool, sore feeling in anus. Next 2 days, no medicine, no symptoms. 25th. – 120 drops in water. For 1/2 hour a hot burning from stomach up through oesophagus; the head, tongue, and saliva symptoms as also the chilliness over back and lower limbs, as before, feet as heavy as lead when sitting and standing; toes of right foot went to sleep when walking; anxious trembling, like vertigo, boiling and simmering through body as if hands and feet would go to sleep, or as when one is one the point of becoming intoxicated with wine, always accompanied by a disagreeable cold feeling. The 2 next days. prostration, confusion of head, and in evening greatly increased temperature of body, with swollen cutaneous veins. 28th. – 140 drops in water, vertigo for 4 hours, burning of tongue. Salivation, burning in stomach, and along oesophagus. Vertigo and stupefaction, general anxiety as if the blood would come out of all the vessels, accompanied by constant chilliness and cold face even in warm room, better in the air, and when moving; stumbling of legs, and feet as heavy as lead, so that he could scarcely walk. Longs to be better, is cross, everything is disagreeable to him; evening, momentary shooting and drawing in sacrum, frequently recurring next day, especially when at rest. 30th. – 140 drops. No symptom except slight burning of tongue, confusion of head, dryness of sauces, with slight increase of saliva. 1st April. – 200 drops. The usual symptoms of tongue and saliva, somewhat less than on previous days; heaviness and weariness of limbs, slight chilliness over back, cold feeling of face, which is hot to the touch; quiet sleep at night. The next 3 days, in which he took no medicine, daily headache in afternoon, and rather restless nights. 5th. – 160 drops in water. After 1/2 hour disgusting sweet taste in fauces, sometimes causing hawking of viscid mucus, sometimes swallowing of it; sensation as if viscid mucus were hanging from uvula, causing inclination to vomit for 1 hour; then the usual pepper taste, that spread from root of tongue gradually all over tongue; at same time increased flow of saliva, when the sweet taste went off; dryness of fauces with irritation to cough that can be suppressed. A kind of numb sensation spread from teeth over cheek-bones to external canthus of eye, and then over almost all the body. The brain seemed to be too large and pressed forcibly on the skull; at same time chilliness over back with predominant coldness and paleness of face. All this lasted 4 to 5 hours, even during a warm bath. The numb feeling of the extremities when at rest went off by walking. Excessive weakness of limbs; staggering of knees; general laziness so that he must drive to his business; frequent ill-smelling eructation with taste of medicine, which always relieved a tensive feeling in pit of stomach;vertigo as from slight, intoxication, with great distraction of thoughts, so that when seeing patients he often became anxious; aggravation in room or when at rest, amelioration in open air and when moving. The next 2 days transient slight drawing shooting pains in left chest, left ear, and later left knee-joint 8th. -108 drops, After 1 hour the usual phenomena in mouth, fauces, oesophagus, stomach, teeth, and face. The wedge-like bursting pain in temporal region slighter, and more of a dull stupefying sensation, making thinking almost impossible and causing a peculiar anxious feeling. During internal chilliness from back over lower limbs, whilst upper limbs are warm, cold sweat occurs; face is icy cold to the touch. The numb feeling of lower limbs, especially of feet and toes, stronger than ever, and even while walking, so that he must often stand still, in order to get rid of this feeling by moving feet backwards and forwards. All this lasted 4 hours. Appetite, throat, and other functions unaffected. In evening, when at rest in unheated room, sensibly increased warmth, quicker pulse, manifest catarrhal symptoms; legs as heavy as lead, especially on going up stairs; staggering, general laziness. (Ibid.)
Hughes was a great writer and a scholar. He actively cooperated with Dr. T.F. Allen to compile his 'Encyclopedia' and rendered immeasurable aid to Dr. Dudgeon in translating Hahnemann's 'Materia Medica Pura' into English. In 1889 he was appointed an Editor of the 'British Homoeopathic Journal' and continued in that capacity until his demise. In 1876, Dr. Hughes was appointed as the Permanent Secretary of the Organization of the International Congress of Homoeopathy Physicians in Philadelphia. He also presided over the International Congress in London.