Introduction
An alkaloid found in several plants, as Chenopodium vulvaria and Arnica montana: also in such fluids as herring-brine, from which the commercial T. (known as “propylamine”) is most frequently obtained. Its formula is C3H9N.
Provings
1. DUJARDIN – BEAUMETZ took 50 centigr. of the chloride of T. in water. Pulse before experiment was 78; after 1 hours it was 76; after 1.1/2 hours 74; after 2 hours 72; after 4 hours 78 again. Temp., 37.4 (centigrade) before experiment, fell to 37.2 after 1 hour, 37 after 1 1/2 hours, 36.8 after 2 hours (ALLEN’s Encyclopaedia, x, 25.)
2. Another person in perfect health took 75 centigr. of same. Pulse, 88 before experiment, was 84 after 1 hour, 82 after 1 1/2 hours, 76 after 2 hours. Diminished force of heart’s action was also shown in tracing taken. Temp., 37degree before experiment, was 36.8 degree after 1 hour, 36.4 degree after 1 1/2 hours, 36degree after 2 hours (Ibid.)
3. I took 10 dr. in water. In 1/2 h. I experienced a smarting sensation of tongue and fauces, with much thirst; there was also a tingling of the fingers, a sensation of numbness to such an extent that in attempting to pick up anything it felt heavy, and I had to use great effort to retain the article within my grasp. This group of symptoms passed off after 3 h. I then took another 10 dr., and experienced the above symptoms intensified, with the addition of great pain in wrist – joints, also great restlessness, yet inability to stand upon my feet from the pain produced in the ankle-joints. I took no more of the medicine, but the tongue became broad and flabby, the mucous membrane of the buccal cavity was pale, appetite gone, no desire for anything; I became morose, with great desire to be let alone. The pain in the joints was made worse by the slightest movement. In 24 hours after taking the drug I was attacked with diarrhoea; stools were thin, watery, and white. (CHAFFEE, U. States Medorrhinum Invest., June 15th, 1880.).